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Öğe Are static posturography-assisted biofeedback exercises effective in Parkinson's disease?(Assoc Arquivos Neuro- Psiquiatria, 2022) Yakşi, Elif; Yaşar, Mustafa Fatih; Türel, Canan Akünal; Balcı, MuhammedBackground Parkinson disease (PD) is a progressive condition that causes disorders in movement and balance.Objective To evaluate the effectiveness of static posturography-assisted biofeedback exercises in PD-related balance disorder.Methods We screened 83 patients, 48 of whom were enrolled, and 41 completed the study. The sample was randomized into two groups, one submitted to static posturography-assisted biofeedback exercises and the other, to a conventional exercise program. The patients in the biofeedback group ( n = 20) performed biofeedback exercises in addition to conventional balance exercises. Those in the conventional exercise group ( n = 21) performed classic balance exercises. Both groups were treated for 20 minutes per session 3 times a week for 6 weeks. The patients were evaluated using the Hoehn and Yahr Scale, the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), the Berg Balance Scale (BBS), the Tinetti Gait and Balance Assessment (TGBA), the Timed Up and Go Test (TUG), the Tandem Stance Test (TST), a Turkish version of the Stanford Health Assessment Questionnaire (HAQ), and the Beck Depression Inventory (BDI) before and at the end of the treatment.Results No statistically significant differences were observed between the two groups in terms of the MDS-UPDRS, BBS, TGBA, TST, TUG, HAQ, or BDI measurements before and after the treatment ( p > 0.05).Conclusions Improved balance parameters were observed following balance training in the patients with PD, although static posturography-assisted biofeedback exercises appeared to provide no additional benefit. However, larger, randomized controlled trials are needed to investigate their effectiveness.Öğe Assessment of Epstein-Barr virus, Candida albicans, and some periodontal pathogens in rheumatoid arthritis patients with periodontitis(Kare Publ., 2023) Paksoy, Tuğçe; Ustaoğlu, Gülbahar; Taşçı, Murat; Demirci, Mehmet; Ünlü, Özge; Yaşar, Mustafa FatihOBJECTIVE: To comparatively investigate the periodontal results and microbial load in subgingival biofilm samples (SBS) in rheumatoid arthritis subjects and healthy volunteers.METHODS: One hundred twenty subjects were classified into different cohorts: healthy (H-C); periodontitis with good systemic health (H-P); rheumatoid arthritis (RA) and good periodontal health (RA-C); and periodontitis with RA (RA-P). The periodontal parameters were recorded, and SBS were collected to determine periodontal pathogens including Epstein-Barr Virus (EBV) and Candida albicans using reverse transcription-polymerase chain reaction (RT-PCR). RESULTS: Subjects that had greater disease course, determined by moderate or high disease activity scores 28 (DAS28), suffered from worse oral health conditions (higher plaque index, gingival index, bleeding on probing, probing depth, and excessive clinical attachment loss) than those with low DAS28 scores. A higher prevalence of Treponema denticola (T. denticola) was observed in the RA-P group. Cyclic citrullinated peptide was associated with the occurrence of T. denticola and Campylo-bacter rectus. DAS28 using C-reactive protein (DAS28-CRP) had a significant association with Capnocytophaga gingivalis and EBV. The duration of the RA disease was associated with the presence of T. denticola.CONCLUSION: Subgingival microbial difference could reliably discriminate RA from healthy individuals. Especially, T. denti-cola and EBV may play a key role in periodontitis associated with RA.Öğe Bone mineral density and vitamin D levels in parkinson’s disease: A retrospective controlled study(2022) Yakşi, Elif; Yaşar, Mustafa FatihObjective: This study aimed to compare bone mineral density and vitamin D levels in patients with Parkinson’s Disease (PD) and healthy controls. Methods: Eighty-six patients aged 60-85, diagnosed with PD and receiving regular medical treatment for the disease were screened. Data for 34 participants (19 women and 15 men) meeting the inclusion criteria were entered into the retrospective analysis. The data for 31 healthy age- and sex-matched participants (18 women and 13 men) were also included. Bone mineral density (BMD) values and vitamin D levels of each participant were recorded. Results: BMD values for the femoral neck and total hip in the PD group were statistically significantly lower than healthy controls. In addition, T-scores for the femoral neck, total hip, and trochanteric area, and Z-scores for the total hip and trochanteric area were also lower in the patients with PD than in the healthy controls. The two groups did not have significant differences regarding lumbar spinal BMD measurements and T- and Z-score values or vitamin D levels. Discussion and Conclusion: PD’s total hip and femoral neck BMD measurements are low. Further multicenter studies involving larger patient populations are now needed to understand the incidence and mechanisms of osteoporosis in PD.Öğe Comparison of dry needling and kinesio taping methods in the treatment of myofascial pain syndrome: A single blinded randomised controlled study(Wiley, 2021) Yaşar, Mustafa Fatih; Yakşi, Elif; Kurul, Ramazan; Alışık, Tuğba; Şeker, ZeynepObjectives The aim of this study was to compare the effectiveness of kinesio taping (KT) and dry needling (DN) in the treatment of myofascial pain syndrome (MPS) of the trapezius muscle. Methods The patients with MPS were divided into 3 groups as those who received exercise only (control group), those who received KT and exercise (KT group) and those who received DN and exercise (DN group) by using a sealed opaque envelope randomisation method. Visual Analog Scale (VAS), Pressure Pain Threshold (PPT), Neck Disability Index (NDI) and Global Perceived Effect Scale (GPES) were measured twice at baseline and at the end of the second week by blinded evaluator. Results A total of 26 patients were assigned to KT group, 32 to DN group and 30 to control group. The results of the study showed that PPT, VAS and NDI scores were significantly improved in the KT (1.61 +/- 1.25, -2.66 +/- 1.24 and -7.08 +/- 6.24, respectively) and DN (1.30 +/- 1.13, -3.34 +/- 1.40 and -10.63 +/- 7.80 respectively) groups (P < .001 for all). In the control group, no significant improvement was found in the VAS (.10 +/- 1.39) and NDI (-.83 +/- 4.91) scores (P > .05), with a significant decrease in PPT (-.98 +/- 1.92) (P = .014). KT and DN methods in MPS treatment have more positive effects in terms of pain, disability and global effect compared to the control group. Conclusions In the treatment of MPS, adding DN or KT to exercise programme may provide important contributions to the treatment.Öğe Comparison of outpatient and inpatient spa therapy in knee osteoarthritis(Springer, 2021) Yaşar, Mustafa Fatih; Yakşi, Elif; Kurul, Ramazan; Balcı, MuhammedOsteoarthritis (OA) is a common condition that impacts many people worldwide and involves weight-bearing joints, resulting in chronic pain. In this study, we aimed to compare the effectiveness of inpatient and outpatient physical therapy modalities and spa combination treatments on pain and functional status in patients with knee osteoarthritis. Seventy-four patients diagnosed with primary knee osteoarthritis were included in this study. The patients were randomized into two groups, inpatient (n = 37) and outpatient (n = 37) physical therapy. All patients received a physical therapy program (superficial heater + deep heater + transcutaneous electrical nerve stimulation) for 2 weeks and spa therapy. All cases were evaluated clinically, laboratory, and radiographically. In order to evaluate pain and functional status, the Visual Analogue Scale (VAS), Western Ontario and McMaster Universities osteoarthritis index (WOMAC), and Timed Up and Go (TUG) test were used before and after treatment. There was no significant difference between the two groups in the TUG test and WOMAC scores (p > 0.05). However, a significant difference was found in VAS scores in favor of the outpatient group (p < 0.05). As a result, although there was a significant improvement in pain scores in the outpatient group, multicenter studies with larger patient groups may provide more evidence.Öğe Comparison of the effectiveness of interferential current and PEMF treatments in patients with chronic mechanical low back pain(2022) Yaşar, Mustafa Fatih; Demirci, ZeynepIntroduction: We aimed to compare the effects of interference current (IFC) and pulsed electromagnetic field (PEMF) therapies combined with conventional physical therapy on pain, functional situation, and quality of life (QOL) in patients with mechanical chronic low back pain (CLBP). Method: In this prospective randomized controlled study, 40 CLBP patients were divided into two groups: group I (Hot pack, ultrasound (US), and IFC combination therapy (n=20)), group II (Hot pack, US, and PEMF combination therapy (n=20)). A total of 10 sessions of therapy were performed on the participants, one session a day, five days a week, for two weeks. Evaluations were performed three times at before the treatment (BT), immediately after the treatment (AT) and 8 weeks after the treatment (AT-8), using the The Numerical Rating Scale (NRS), Roland-Morris Disability Questionnaire (RMDQ), EuroQol-Health-related Quality of Life Questionnaire (EQ-5D-3L), Fingertip-to-floor test (FtF). Results: There was no difference in age, BMI, gender and baseline values in all two groups. No significant difference was found for RMDQ (F(2.76)=0.174; P=0.840), NRS(F(2.76)=0.155; P=0.857), and EQ (F(2.76)=0.273; P=0.762) scores in time–group interaction (F(2.76)=0.174; P=0.840). No significant differences were found between the groups in terms of RMDQ, NRS, EQ-5D-3L, and FtF scores (p>0.05). Discussion and Conclusion: It has been proved that PEMF or IFC therapies in addition to conventional physical therapy programs are effective in mechanical CLBP treatment in terms of pain, functional status, and quality of life.Öğe Comparison of the Efficacy of Corticosteroid and Local Anesthetic Injections Combined with Physiotherapy in Patients with Concomitant Pes Anserine Bursitis and Knee Osteoarthritis: A Prospective Randomized Study(2022) Yaşar, Mustafa Fatih; Kurul, Ramazan; Yakşi, Elif; Aydilek, Merve; Ates, Zeynep; Tonuk, Sukru BurakObjectives: It was aimed to investigate the effects of local corticosteroid and local anesthetic injection in patients with concomitant pes anserine bursitis and knee osteoarthritis.\rMethods: In this prospective randomized controlled study, 102 patients with knee osteoarthritis with pes anserine bursitis were divided into three groups: group I (physiotherapy + lidocaine), group II (physiotherapy + betamethasone dipropionate), and group III (physiotherapy: control). Evaluations were performed three times at the start of treatment, \rat day 15, and at week eight, using the Visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis index (WOMAC), and the Timed up and go (TUG).\rResults: There was no difference in age, BMI, gender and baseline values in all three groups. There was a significant difference between the groups in pre and post treatment VAS and WOMAC scores (p<0.05). However, there was no difference between the groups in the post-test follow-up values (p>0.05). While betamethasone significantly decreased \rVAS and WOMAC scores, only WOMAC scores were decreased in the lidocaine group. There was no significant difference between the WOMAC scores of the lidocaine and betamethasone groups (p>0.05).\rConclusion: Corticosteroids and lidocaine are avaiable choices to relieve pain, our results show, corticosteroids are more effective. Consequently, steroids may be considered as a better option in patients with concomitant pes anserine bursitis and knee osteoarthritis.Öğe Diz osteoartritinde Pulse Elektromanyetik Alan Tedavisi (PEMF) ile Transkütanöz Elektriksel Sinir Stimülasyonu (TENS) tedavisinin ağrı ve fonksiyonellik üzerine etkilerinin karşılaştırılması(Bolu Abant İzzet Baysal Üniversitesi, 2010) Yaşar, Mustafa Fatih; Tönük, BurakBizim çalışmamızın amacı, kullanımı kolay, önemli kontraendikayonu bulunmayan alternatif tedavi yöntemi PEMF'in, diz osteoartritinde ağrı ve fonksiyonel durum üzerine olan etkinliğini araştırmak ve TENS ile karşılaştırmaktır.Amerikan Romatoloji Derneği (ACR) kriterlerine göre `primer diz osteoartriti' tanısı konulmuş, 38 yaş üzerinde olan ve son 1 yıl içinde fizik tedavi programı uygulanmamış 48 semptomatik olgu çalışmaya alındı. Tüm olgular klinik, laboratuvar ve radyografik olarak değerlendirildiHastalar randomizasyon yöntemiyle her biri 24 kişiden oluşan 2 gruba ayrılarak ilk gruba 30 dakika süreyle 100 Hz frekansta TENS terapisi uygulandı. İkinci gruba ise 24 dakika süre ile 50 Hz frekansta, 60 mikrotesla şiddet ile PEMF uygulandı. Olgular, iki hafta boyunca, haftada 5 gün, günde bir seans olmak üzere uygulama yapıldı. Her iki gruptaki olgulara kombinasyon tedavisi olarak 20 dk hotpack ve 1,5 W/cm2 US 6 dk uygulanmıştır.Gruplar (Grup1:Hotpack+US+TENS, Grup2:Hotpack+US+PEMF) tedavi öncesi ve tedavi sonrasında VAS, WOMAC ve Lequesne skalaları ile değerlendirilmiştir. Her iki grupta da VAS, WOMAC indeks ve Lequesne skala skorunda tedavi sonrasında tedavi öncesine göre anlamlılık arzeden düzelme izlendi (p<0.05). Tedavi öncesi VAS, WOMAC indeks ve Lequesne skala ile tedavi sonrası VAS, WOMAC indeks ve Lequesne skala iki grup arasında karşılaştırıldığında anlamlı değildi. Çalışmamızda WOMAC indeks ve Lequesne skala alt grupları her iki tedavi grubu için ve gruplar arası değerlendirilmiştir. Her iki kombinasyon tedavisinin de etkinliğinin bulunduğu ancak birbirlerine üstünlüğünün olmadığı görülmüştür. Sonuç olarak çalışmamız PEMF tedavisinin diz osteoartritinde alternatif bir tedavi yöntemi olduğu ve tedavi protokollerine eklenebilecek ucuz, güvenilir bir metod olduğunu desteklemiştir.Anahtar Kelimeler: Pulse elektromanyetik alan, diz, osteoartrit, TENSÖğe Diz Osteoartritinde Pulse Elektromanyetik alan tedavisi ile Transkutanöz Elektriksel Sinir Stimülasyonu tedavisinin ağrı ve fonksiyonellik üzerine etkilerinin karşılaştırılması: Randomize klinik çalışma(2018) Yaşar, Mustafa Fatih; Tönük, Şükrü BurakAmaç: Diz osteoartrit tanısı almış hastalarda yüzeyel sıcak ve diatermi tedavilerine ek olarak uygulanan transkutanöz elektriksel sinir stimülasyon (TENS) ile yüzeyel sıcak ve diatermi tedavilerine ek olarak uygulanan pulse elektromanyetik alan (PEMF) tedavisinin ağrı ve fonksiyonel durum üzerine etkilerini karşılaştırmaktır. Gereç ve Yöntemler: Çalışmaya 48 semptomatik diz osteoartitli hasta dâhil edildi. Hastalar, kapalı zarf yöntemi ile TENS (n=24) ve PEMF (n=24) grupları olarak ikiye ayrıldı. Birinci gruba 100 Hz frekansta, 30 dakika/seans TENS uygulandı. İkinci gruba ise 50 Hz frekansta, 60 mikrotesla şiddet ile 24 dakika/seans PEMF uygulandı. Her iki gruba da iki hafta boyunca, haftada beş gün, günde bir seans yüzeyel sıcak (sıcak paket, sıcak toleransa göre, 20 dakika/seans) ve diatermi (ultrason 1,5 W/cm2 6 dakika/seans) uygulandı. Değerlendirmeler başlangıçta ve tedavi sonunda yapıldı. Sonuç ölçümleri olarak, vizüel analog skala (VAS) (0-100), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) ve Lequesne Skalası kullanıldı. Bulgular: Her iki grupta da VAS, WOMAC indeks ve Lequesne skala skorunda tedavi sonrasında tedavi öncesine göre anlamlı düzelme izlendi (p<0.05). Tedavi öncesi ve tedavi sonrası ölçüm değerleri farkının gruplar arası karşılaştırılmasında, TENS ve PEMF grupları arasında VAS (p=0,109), WOMAC (p=0,427) ve Lequesne (p=0,264) skorlarına göre istatistiksel olarak anlamlı fark bulunmadı. Sonuç: Çalışmamız konvansiyonel tedaviye ek olarak uygulanan TENS ve PEMF’nin her ikisinin de diz OA semptomlarını iyileştirmede etkili olduğunu göstermiştir. PEMF ve TENS’nin benzer etki düzeyine sahip olduğu saptanmıştır.Öğe Effect of leap motion based 3D immersive virtual reality usage on upper extremity function in ischemic stroke patients(Assoc Arquivos Neuro- Psiquiatria, 2019) Ögün, Muhammed Nur; Kurul, Ramazan; Yaşar, Mustafa Fatih; Türkoğlu, Şule Aydın; Avcı, Şebnem; Yıldız, NebilImmersive virtual reality (VR) is a technology that provides a more realistic environmental design and object tracking than ordinary VR. The aim of this study was to investigate the effectiveness of immersive VR on upper extremity function in patients with ischemic stroke. Sixty-five patients with ischemic stroke were included in this randomized, controlled, double-blind study. Patients were randomly divided into VR (n = 33) and control (n = 32) groups. The VR group received 60 minutes of the upper extremity immersive VR rehabilitation program and the control group received 45 minutes of conventional therapy and 15 minutes of a sham VR program. Rehabilitation consisted of 18 sessions of therapy, three days per week, for six weeks. The outcome measures were the Action Research Arm Test (ARAT), Functional Independence Measure (AM), Fugl-Meyer Upper Extremity Scale (FMUE) and Performance Assessment of Self-Care Skills (PASS). In both the VR and control groups all parameters except the PASS improved over time. However independent t-test results showed that all of the FMUE, ARAT, FIM and PASS scores were significantly higher in the VR group compared with the control (p < 0.05). The minimal clinically important difference (MCID) scores of the FMUE and ARAT were higher than the cut-off MCID scores described in the literature in the VR group, whereas the AM scores were below the cut-off MCID scores. All scores in the control group were below the cut-off scores. Immersive VR rehabilitation appeared to be effective in improving upper extremity function and self-care skills, but it did not improve functional independence.Öğe The Effect of Occupational Therapy on Upper Extremity Function and Daily Life Activities in Stroke Patients(2022) Aydilek, Merve; Yaşar, Mustafa Fatih; Yakşi, ElifObjective: This study aims to assess the effectiveness of occupational therapy (OT) added to standard rehabilitation treatments on hemiplegic stroke patients' daily life activities and upper extremity functions. \rMaterial and Methods: This prospective, randomized, controlled clinical \rstudy included 50 patients aged between 20 and 80 who had suffered a \rstroke and developed hemiplegia due to cerebrovascular accident and applied to Bolu Abant İzzet Baysal University Physical Therapy and Rehabilitation Hospital. The study patients were divided into two groups: an OT \r[treatment] group receiving standard rehabilitation (five days a week for six \rweeks) and OT (three days a week for six weeks, 45 minutes per day) and \ra standard treatment (ST) [control] group receiving standard rehabilitation \ronly. All patients were evaluated before (at initial) and after the treatment \r(at the end of the 6-week treatment). The Barthel Index (BI), Fugl-Meyer \rAssessment of Motor Recovery (FMA) Scale, and Action Research Arm \rTest (ARAT) were used to investigate treatment effectiveness. Results: \rThere was a significant increase in the post-treatment (at the end of the 6-\rweek treatment) BI, FMA Scale, and ARAT scores in both OT and ST \rgroups compared to the pre-treatment (at initial) scores. The FMA scale and \rARAT scores significantly differed between groups 6 weeks after the treatment; the post-treatment ARAT and FMA scale scores were statistically significantly higher in the OT group than in the ST group. No significant \rdifference was found between the groups in pre-treatment and post-treatment BI scores. Conclusion: The present study revealed that occupational \rtherapies added to the standard rehabilitation practices contribute to developing motor functions of the upper extremity in hemiplegic stroke patientÖğe Effect of pulsed electromagnetic field therapy in patients with supraspinatus tendon tear(ASSOC MEDICA BRASILEIRA, 2021) Özdemir, Mesut; Yaşar, Mustafa Fatih; Yakşi, ElifOBJECTIVE: The aim of this study was to compare the effect of transcutaneous electrical nerve stimulation (TENS), ultrasound (US), and pulsed electromagnetic field (PEMF) combination with TENS and US therapy alone in patients with supraspinatus tear. METHODS: Forty patients were included in this study. The patients were randomly divided into two groups as follows: PEMF (n=20) and Sham (n=20) groups. PEMF was applied to the first group at a frequency of 50 Hz, 25 G intensity, and 20 min/session. The device was turned off while PEMF was applied to the second group. Diathermy (US) and electrotherapy (TENS) were applied to both groups for 10 sessions. Numerical Rating Scale (NRS), University of California-Los Angeles (UCLA) Shoulder Scale, and Shoulder Pain and Disability Index (SPADI) were used as outcome measures. RESULTS: In both groups, there was a significant improvement in the NRS, UCLA Shoulder Scale, and SPADI scores after treatment compared with pretreatment (p<0.05). In the comparison of the difference between the pretreatment and posttreatment measurement values between the groups, no significant difference was found between PEMF and Sham groups according to the NRS (p=0.165), UCLA Shoulder Scale (p=0.141), and SPADI (p=0.839) scores. CONCLUSIONS: In our study, a combination of PEMF therapy with conventional physical therapy modalities was not found to be superior to the conventional therapy alone, and adding it to the routine treatment of symptomatic supraspinatus tear would not provide any additional benefit.Öğe The effect of robot-assisted gait training frequency on walking, functional recovery, and quality of life in patients with stroke(Springer, 2023) Yakşi, Elif; Bahadır, Elif Selim; Yaşar, Mustafa Fatih; Alışık, Tuğba; Kurul, Ramazan; Demirel, AdnanAimThis study aims to investigate the effects of robot-assisted gait training (RAGT) frequency on walking, functional recovery, QoL and mood.MethodsSixty patients aged 50-75, diagnosed with post-stroke hemiplegia were entered into the retrospective analysis. Participants who scored maximum 3 on the Modified Rankin Scale and were diagnosed with moderate stroke according to The NIH Stroke Scale were included in the study. The participants in group 1 (G1) received only conventional treatment (CT), in group 2 (G2) participants received one session of RAGT per week in addition to the CT program, and group 3 (G3) received two sessions of RAGT per week in addition to the CT program. 6-min walk test (6-MWT), Barthel Index (BI), Stroke-Specific Quality of Life Scale (SSQoL), and Beck Depression Inventory (BDI) were recorded.ResultsMedian change in SSQoL of G3 was significantly higher from median change of G1 (p < 0.05), and median change in BDI of G3 was significantly lower than median change of G1 (p < 0.05). Median change in BDI of G3 was also significantly lower from change of G2 (p < 0.05).ConclusionTwo weekly sessions of RAGT in addition to CT exhibit positive effects on QoL and mood but no additional contribution to functional status.Öğe Evaluation of autonomic nervous system dysfunction in fibromyalgia(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2011) Şahin, Özlem; Yıldız, Serpil; Yıldız, Nebil; Yaşar, Mustafa Fatih; Kaptanoğlu, EceObjective: There have been conflicting results of studies on autonomic nervous system (ANS) dysfunction in fibromyalgia (FM). The aim of this study was to evaluate the sympathetic nervous system dysfunction via sympathetic skin response (SSR) recordings in patients with FM. Materials and Methods: Twenty-seven female patients with FM and 18 healthy volunteer females as controls were included in the study. All participant were administered the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI) and were questioned about chronic symptoms that are characteristic for FM. Right palmar SSRs were evoked by electrical stimulation of the median nerve at the wrist. Results: The FM patients had higher rates of most of the chronic symptoms of FM. There was no significant difference in SSR latency and amplitude between patients and controls (p>0.05). The patients with FM had no depression and anxiety according to the BDI and BAI mean scores. Conclusion: We did not find ANS dysfunction in the patients with FM. SSR may be an insufficient way of determining the whole ANS dysfunction as it only evaluates the sudomotor component. ANS dysfunction may be responsible for some of the chronic symptoms of FM and accompanying depression and anxiety (not observed in the present study) rather than taking part in the etiopathogenesis. It can be possible to determine the role of ANS in FM etiopathogenesis by studies evaluating the subsystems of ANS (cardiovascular reflex pathway, sympathetic cholinergic activity etc.) in which chronic symptoms of FM, especially anxiety and depression, are also considered. Turk J Phys Med Rehab 2011;57:62-5.Öğe Evaluation of autonomic nervous system dysfunction in fibromyalgia(2011) Şahin, Özlem; Yildiz, Serpil; Yildiz, Nebil; Yaşar, Mustafa Fatih; Kaptanoğlu, EceAmaç: Fibromyaljide (FM) otonom sinir sistemi (OSS) disfonksiyonu hakkındaki çalışmaların farklı sonuçları vardır. Bu çalışmadaki amacımız sempatik deri yanıtı (SDY) cevaplarını kullanarak FM hastalarında sempatik sinir sistemi disfonksiyonunu değerlendirmektir. Gereç ve Yöntem: Çalışmaya 27 fibromyaljili kadın hasta ve 18 sağlıklı gönüllü kadın kontrol alındı. FM hastaları ve sağlıklı kişiler Beck Depresyon Envanteri (BDE), Beck Anksiyete Envanteri (BAE) ve FM için karakteristik olan kronik semptomlar yönünden sorgulandı. Sağ el palmar SDY, median sinirin bilek hizasında elektriksel olarak uyarılması ile elde edildi. Bulgular: FM hastalarında kronik semptomların çoğu yüksek orandaydı. Hastaların ve kontrollerin SDY amplitüd ve latansları arasında istatistiksel olarak anlamlı bir fark yoktu (p>0,05). BDE ve BAE ortalama değerlerine göre FM hastalarında anksiyete ve depresyon yoktu. Sonuç: Bu çalışmada FM’de OSS disfonksiyonu tesbit edilmedi. SDY sadece sudomotor aktiviteyi gösterdiği için OSS’nin tamamını değerlendirmede yetersiz bir yöntem olabilir. OSS disfonksiyonu FM’nin etyopatogenezinden ziyade FM’de gözlenen bazı kronik semptomlardan, eşlik eden depresyon ve anksiyeteden sorumlu olabilir. FM hastalarının kronik semptom, anksiyete ve depresyon durumları da gözönünde bulundurularak, OSS’nin alt sistemlerini (kardiyovasküler refleks yol, sempatik kolinerjik aktivite gibi) inceleyen çalışmalar ile OSS’nin FM etyopatogenezindeki rolünü belirlemek mümkün olabilir.Türk Fiz Tıp Rehab Derg 2011;57:62-5.Öğe Günlük yaşamda boyun fleksiyonu gerektiren aktiviteler ile servikal omurga dizilim bozukluğu arasındaki ilişki(2010) Şahin, Özlem; Kıyan, Aysu; Yaşar, Mustafa Fatih; Taşlıgil, Cemal; Çoğalgil, Şirzat; Tönük, Şükrü BurakAmaç: Günlük yaşamda boynu fleksiyona zorlayan aktivitelerin servikal omurgada dizilim bozukluğuna neden olup olmadığını araştırmaktır. Yöntemler: Çalışmaya kronik boyun ağrısı şikayeti olan 104 olgu alındı. Servikal omurgada düzleşme ya da kifotik deformite olması dizilim bozukluğu olarak kabul edildi. Servikal omurgadaki dizilim bozukluğu, posteriyor tanjant metoduna göre yan servikal omurga grafisinin değerlendirilmesi ile belirlendi. Boynu fleksiyona zorlayan aktiviteler sırt üstü yatarak televizyon seyretme ve sırt üstü yatarak ve oturarak kitap okuma aktiviteleri olarak belirlendi. Bulgular: Dizilim bozukluğu olan grupta 32 olgu (%68,1) sırt üstü yatarak televizyon seyrediyordu, 9 olgu (%19,1) sırt üstü yatarak kitap okuyordu, 20 olgu (%42,6) oturarak kitap okuyordu. Dizilim bozukluğu olmayan grupta, 32 (%71,1) olgu sırt üstü yatarak televizyon seyrediyordu, 8 (%17,8) olgu sırt üstü yatarak kitap okuyordu, 13 (%28,9) olgu oturarak kitap okuyordu. Gruplar arasında sırt üstü yatarak televizyon seyretme, sırt üstü yatarak ve oturarak kitap okuma dağılımına bakıldığında istatistiksel olarak anlamlı farklılık tespit edilmedi (p>0,05). Sonuç: Bu çalışmanın bulgularına göre boynu sıkça fleksiyona zorlayan aktiviteler, servikal omurgada dizilim bozukluğuna neden olmamaktadır. Dizilim bozukluğu, sorguladığımız aktiviteler dışında boynu fleksiyona zorlayan başka aktiviteleri ya da bireylerin omurga stabilitesini sağlayan kas ve bağ yapılarındaki olası güçsüzlüğü akla getirmektedir. Bu konuda kesin yargıya varmak için daha fazla sayıda olgu katılımının olduğu, boynu fleksiyona zorlayan aktivitelerin sorgulandığı ve egzersizin de etkilerinin incelendiği prospektif çalışmalara ihtiyaç vardır.Öğe Kronik Bel Ağrılı Hastalarda Düşük Yoğunluklu Lazer Tedavisinin Etkinliğinin Araştırılması(2022) Atli, Zehra; Yakşi, Elif; Yaşar, Mustafa FatihAmaç: Bu çalışmanın amacı; kronik bel ağrılı hastalarda düşük yoğunluklu lazer (DYL) tedavisinin ağrı, fonksiyonel durum ve yaşam kalitesi üzerine etkilerini araştırmaktır.Materyal ve Metot: Çalışmaya, üç aydan uzun süre bel ağrısı şikayeti olan, 18-65 yaş arası 40 hasta dahil edildi. Hastalar randomize olarak iki gruba ayrıldı. Birinci gruptaki hastalara (n=20) DYL+egzersiz tedavisi; ikinci gruptaki hastalara (n=20) yalnızca egzersiz tedavisi 15 seans olacak şekilde uygulandı. Hastalar tedavi öncesi (TÖ) ve tedavi sonrası (TS) dönemde değerlendirildi. Hastaların ağrı şiddeti değerlendirmesi Vizüel Analog Skala (VAS) ile, fonksiyonel durumu Modifiye Oswestry Bel Ağrısı Engellilik Anketi (MOS) ile, yaşam kalitesi ise Short Form-36 (SF-36) ile değerlendirildi.Bulgular: Her iki grupta VAS ve MOS skorlarında TS’de TÖ’ye oranla istatistiksel olarak anlamlı azalma saptandı (p<0,05). Gruplar arası karşılaştırmada VAS ve MOS değerlerinde TS ’de DYL lehine istatistiksel olarak anlamlı düzelme saptandı (p<0,05).Sonuç: Kronik bel ağrısında DYL tedavisinin ağrı kontrolü ve fonksiyonel durumda iyileşmede etkili olduğu gösterilmiş olsa da yaşam kalitesi üzerine etkileri saptanamamıştır. Bu konuda daha geniş kapsamlı, randomize kontrollü çalışmalara ihtiyaç vardır.Öğe The prevalence of temporomandibular disorders among medical students(2023) Yakşi, Elif; Demirel, Adnan; Yaşar, Mustafa Fatih; Kilinç, Serdar; Balci, MuhammedObjective: This study aimed to evaluate the frequency of temporomandibular disorders (TMD) among students at the Abant Izzet Baysal University Medical Faculty in Turkey. Material and Method: Two hundred eleven medical students aged between 18 and 30 were included in the study. The presence and severity of TMD were evaluated using the Fonseca Anamnestic Index (FAI). Parafunctional habits, bruxism, and orthodontic treatments potentially associated with TMD were investigated. Results: No TMD was determined in 87 (41.2%) of the participants, mild TMD in 82 (38.9%), moderate TMD in 37 (17.5%), and severe TMD in five (2.4%) in the evaluations performed using the FAI. The frequency of TMD was significantly higher in women compared to men (p<0.05). The incidences of parafunctional habits and self-reported bruxism were significantly higher among participants with TMD compared to those with no TMD (p<0.05). The severity of TMD also increased significantly in the presence of parafunctional habits and bruxism (p<0.05). Conclusions: The incidence of TMD among medical students was 59% and female gender, parafunctional habits, and bruxism were found to be associated with the disorders.Öğe The relationship of monocyte to high density lipoprotein-cholesterol ratio and complete blood count parameters with radiologic staging of knee osteoarthritis(2022) Yaşar, Mustafa Fatih; Yakşi, ElifAim: To evaluate the predictive ability of bioindicators derived from complete blood count (CBC) parameters\rand monocyte-high density lipoprotein-cholesterol ratio (MHR) in the diagnosis of radiological stage of knee\rosteoarthritis (OA) in this study.\rMethod: This cross-sectional retrospective study was carried out between November 2017 and June 2021, in\rour physical therapy and rehabilitation clinics. 65 patients knee x-rays and routine laboratory results were\rincluded in the study. Each knee x-rays were assigned a grade from 0 to 4 (Kellgren-Lawrence Classification\rSystem (KL). Patients were divided into two groups according to severity of the knee OA as follows. Group\r1: Mild-moderate OA (KL Grade1-2), Group 2: Severe OA (KL Grade 3-4).\rResults: Independent T test and Mann Whitney U test were used to assess whether there was a difference in\rCBC parameters and their derivatives between two groups. Platelet lymphocyte ratio (PLR), red cell\rdistribution width (RDW) to platelet ratio (RPR) and platelet (PLT) counts indicated statistically significant\rdifferences between the groups, p-values were 0.04, 0.03 and 0.04 respectively. There were no significant\rdifferences in terms of MHR score between the groups.\rConclusions: We could not find a relationship between MHR and radiological degree of knee osteoarthritis.\rHowever, there is a correlation between radiological stage of knee osteoarthritis and hemogram parameters\rlike PLT and their derivatives such as PLR and RPR.
