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    The relationship between Choroidal Vascular Index and non-invasive ultrasonographic atherosclerosis predictors
    (Elsevier, 2024) Bayraktar, Muhammet Fatih; Toprak, Guvenc; Alkan, Yunus
    Background: This study explores the intricate connections between choroidal vascular index (CVI) and noninvasive ultrasonographic atherosclerosis predictors, shedding light on the potential links between ocular vascular dynamics and systemic cardiovascular health. Methods: We conducted a cross-sectional analysis of 81 participants, assessing CVI, intima-media thickness (IMT), extra -media thickness (EMT), and the PATIMA index. The presence of coronary artery disease (CAD) was also evaluated. Statistical methods included descriptive statistics, t -tests for group comparisons, Spearman correlation analysis, and receiver operating characteristic (ROC) curve analysis. Results: Our findings revealed that patients with CAD had lower CVI values compared to those without CAD, underscoring a potential association between CVI and CAD. Significant negative correlations were observed between CVI and IMT, EMT, PATIMA, and CAD. ROC curve analysis identified optimal CVI cutoff values for hypertension and CAD detection, showcasing its potential as a diagnostic marker. Discussion: Our results align with existing literature on ocular vascular changes, supporting the notion that CVI may be a promising indicator of systemic vascular conditions. The study contributes to the broader understanding of the relationships between ocular and cardiovascular health, providing a foundation for future research and clinical applications. Conclusion: The study suggests that CVI holds clinical relevance as a non-invasive marker for identifying systemic conditions, offering insights into the fields of neurology, physical therapy, and rehabilitation. Addressing its limitations, this research encourages further investigation into the multifaceted connections between CVI and atherosclerosis predictors.
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    The relationship between epicardial adipose tissue and choroidal vascularity index in patients with hypertension
    (Clinics Cardive Publ Pty Ltd, 2023) Toprak, Guvenc; Bayraktar, Muhammet Fatih
    Objective: The choroidal vascularity index (CVI) is a method that measures the density of blood vessels in the choroidal layer and can be used to evaluate the effects of hypertension. In this study we aimed to investigate the relationship between epicardial fat thickness (EFT) and CVI in patients with hypertension. Methods: This prospective study included 112 patients diagnosed with hypertension and 120 healthy individuals. Patients' demographic data such as age, gender, weight, height, body mass index (BMI), smoking status, and presence of coronary artery disease and diabetes mellitus were recorded. BMI was calculated by dividing a patient's weight in kilograms by their height in metres squared. EFT was measured by echocardiography and CVI was calculated using the optical coherence tomography method.Results: The mean CVI was found to be 66.57 +/- 2.21 in the patient group and 69.22 +/- 2.39 in the control group and the difference was significant (p < 0.001). The mean EFT was found to be 5.23 +/- 3.25 mm in the patients and 2.57 +/- 1.97 mm in the control group and the difference was statistically significant (p = 0.003). According to Spearman's correlation analysis, there was a significant positive correlation between BMI and EFT (r = 0.379, p < 0.001) and a significant negative correlation between CVI and EFT (r = -0.412, p < 0.001). Conclusion: The CVI value was significantly lower and the EFT value was significantly higher in patients with hypertension compared to non-hypertensive patients. There was a significant positive correlation between EFT and BMI and a significant negative correlation between EFT and CVI.