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Öğe Effect of exercise on appetite-regulating hormones in overweight women(Inst Sport, 2013) Tiryaki-Sönmez, Gül; Özen, Şerife; Buğdaycı, Güler; Karlı, Ümid; Özen, Güçlü; Çoğalgil, Şirzat; Schoenfeld, Brad; Sözbir, Kerim; Aydın, KutluOver the past decade, our knowledge of how homeostatic systems regulate food intake and body weight has increased with the discovery of circulating peptides such as leptin, acyl ghrelin, des-acyl ghrelin and obestatin. These hormones regulate the appetite and food intake by sending signals to the brain regarding the body's nutritional status. The purpose of this study was to investigate the response of appetite-regulating hormones to exercise. Nine overweight women undertook two 2 h trials in a randomized crossover design. In the exercise trial, subjects ran for 60 min at 50010 of maximal oxygen uptake followed by a 60 min rest period. In the control trial, subjects rested for 2 h. Obestatin, acyl ghrelin, des-acyl ghrelin and leptin concentrations were measured at baseline and at 20, 40, 60, 90 and 120 min after baseline. A two-way ANOVA revealed a significant (P<0.05) interaction effect for leptin and acyl ghrelin. However, changes in obestatin and des-acyl ghrelin concentration were statistically insignificant (P>0.05). The data indicated that although acute treadmill exercise resulted in a significant change in acyl ghrelin and leptin levels, it had no effect on plasma obestatin and des-acyl ghrelin levels.Öğe The effects of exercise on food intake and hunger: Relationship with acylated ghrelin and leptin(Journal Sports Science & Medicine, 2011) Vatansever-Özen, Şerife; Tiryaki-Sönmez, Gül; Buğdaycı, Güler; Özen, GüçlüThis study investigated the effects of a long bout of aerobic exercise on hunger and energy intake and circulating levels of leptin and acylated ghrelin. Ten healthy male subjects undertook two, 4 h trials in a randomized crossover design. In the exercise trial subjects ran for 105 min at 50% of maximal oxygen uptake and the last 15 min at 70% of maximal oxygen uptake followed by a 120 min rest period. In the control trial, subjects rested for 4 h. Subjects consumed a buffet test meal at 180 min during each trial. Hunger ratings, acylated ghrelin, leptin, glucose and insulin concentrations were measured at 0, 1, 2, 3 and 4 h. No differences were found at baseline values for hunger, acylated ghrelin, leptin, insulin and glucose for both trials (p > 0.05). The estimated energy expenditure of the exercise trial was 1550 +/- 136 kcal. Exercise did not change subsequent absolute energy intake, but produced a significant decrease (p < 0.05) in relative energy intake. A two-way ANOVA revealed a significant (p < 0.05) interaction effect for hunger and acylated ghrelin. In conclusion, this exercise regimen had a positive effect on reducing appetite which is related to reduced acylated ghrelin responses over time. This finding lends support for a role of exercise in weight management.Öğe Exercıse and hormones related to appetıte regulatıon(American-Eurasian Network for Scientific Information, 2015) Ölçücü, Burçin; Vatansever, Şerife; Tiryaki-Sönmez, Gül; Schöenfeld, Brad JonBackground: Obesity is spreading all around the world rapidly, especially in developed and developing countries, due to physical inactivity related to technological developments and increase in the consumption on energy rich food. Discovery of the new stimulants that affect various parts of the hypothalamus and produced from some peripheral tissues, and understanding of their functions better increase our knowledge of energy homeostasis. Objective: Especially, the discovery of obese gene (16kDa, ob) product released from adipose tissue, discovery of leptin known as satiety hormone, the discovery of ghrelin known as hunger hormone, and the discovery of obestatin, which is the product of the same gene with ghrelin and thought to resist the effects of ghrelin on food intake started a new era about the opinions on obesity. Results: Exercise is a nonpharmacological method used by itself or along with food-intake limitation in obesity treatment and body weight control. This review will attempt to update the knowledge of ghrelin, leptin and obestatin on the body weight regulation and the effect of exercise training on ghrelin, leptin and obestatin concentration. In conclusion, Conclusion: findings of the current studies on acute and chronic exercise conducted on human subjects that examined the effect of exercise on ghrelin, leptin and obestatin contradict with each other. Some of these differences may have resulted from differences between intensity, duration, and type of the exercise, or the features of the subjects, different research designs such as time of food intake. For this reason, many more studies using various subject groups and different methods are required in the subject field. © 2015 AENSI Publisher All rights reserved.Öğe Impact of exercise modes on appetite markers(Kamla-Raj Enterprises, 2015) Vatansever, Şerife; Ölçücü, Burçin; Tiryaki-Sönmez, GülThis study investigates the effects of different acute exercise modes on appetite marker ratings. Twelve healthy male subjects participated voluntarily in the study and written informed consent was obtained from all subjects before participation. The subjects underwent four, 120 minute trials (exercise and control) in a randomized crossover design. These included three exercises and one control. In the exereise trials, the subjects performed three different exercise protocols (60 minutes exercise and 60 minutes recovery). In the control trial, subjects rested for 2 hours. The ratings of subjective feelings of appetite markers were reported on 100 mm visual analogue scales (VAS) at baseline and at 20, 40, 60,80, 90, 120 minutes after baseline. The visual analogue scales (VAS) were used to measure the following appetite markers: (i) hunger, (ii) fullness, (iii) desire to eat, and (iv) prospective food consumption. Repeated-measures, and two-factor ANOVA were used to examine differences between the four trials over time to note appetite marker changes. Between-trial differences at each time point were examined using a one-way ANOVA and the Bonferroni post hoc tests when significant interactions were found. The two-way ANOVAs revealed significant (P<0.05) trial x time effects (P<0.05) and time (P<0.05) effects in all appetite markers except hunger. The exercise modes are not different from control (P>0.05) in any of the appetite markers except for the feeling of satiety, and the differences between exercise modes are that, cornbined exercises decrease the feeling of satiety more than combined exercises, and caused desire to eat and prospective food consumption more than resistance exercises (P<0.05). In conclusion, this finding lends support for a role of exercise in weight management.Öğe Salivary antioxidant capacity during exercise in athletes(Wiley-Blackwell, 2009) Buğdaycı, Güler; Koç, Önder; Yüktaşır, Bekir; Öze, Şerife; Yalçın, Hasan Birol; Tiryaki-Sönmez, Gül[No Abstract Available]