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Öğe Comparison of a novel trephine drill with conventional rotary instruments for maxillary sinus floor elevation(Quintessence Publishing Co Inc, 2013) Kazancıoğlu, Hakkı Oğuz; Tek, Mustafa; Ezirganli, Şeref; Mihmanli, AhmetPurpose: The purpose of this study was to compare a newly designed trephine drill (SLA KIT, Neobiotech) with conventional rotary instruments for maxillary sinus floor elevation based on operative time, postoperative pain, and perforation rates. Materials and Methods: Twenty-five patients were treated with a bilateral sinus floor elevation procedure with rotary trephine and conventional instruments. One side was treated with conventional rotary instruments, while the contralateral side was treated with rotary trephine instruments, with a 2-week gap between surgeries. Operative time was measured with a chronometer in seconds as the time from soft tissue incision to primary closure of the incision with the last suture. Pain was scored on a 10-point visual analog scale at 24 hours after surgery. The presence of tears and perforations was determined by direct visualization and the Valsalva maneuver. Results: Twenty-five patients were included in the study. Operative time was shorter when the trephine drill was used (11.1 +/- 2.4 minutes) than with conventional rotary instruments (15.1 +/- 2.9 minutes). Sinus membrane perforation was observed in eight patients when conventional rotary instruments were used, while the trephine drill resulted in two sinus perforations. Mean pain scores were 2.01 +/- 0.11 after using the trephine drill and 2.25 +/- 0.76 when conventional rotary instruments were used. No significant difference was found in postoperative pain scores. Conclusion: The trephine drill technique may result in decreased perforation rates and operative time.Öğe Complex and compound odontomas : analysis of 69 cases and a rare case of erupted compound odontoma(Wolters Kluwer Medknow Publications, 2015) Bereket, Cihan; Çakır-Özkan, Nilüfer; Şener, İsmail; Bulut, Emel; Tek, MustafaObjective: The purpose of this study was to analyze clinic and radiologic features of the 69 odontoma cases and present a rare case of erupted compound odontoma in the oral cavity. Material and Methods: The 69 cases were analyzed with regard to the following parameters: age, gender, location, associated unerupted teeth, missing teeth, radiological and histopathological features and treatment protocols. Results: Of the 69 cases, 49 were compound odontoma and 20 were complex odontoma. There was a female predilection for both compound and complex odontomas. Compound odontoma occurred more often in the anterior region of the jaws; complex lesions occurred more often at the posterior mandible. The most common clinical manifestations were the retention of permanent teeth. Conclusion: Compound odontomas rarely erupt into the mouth. The presented case is the 13th case of erupted compound odontoma reported in the literature. The treatment of choice is surgical removal of the odontoma. In the case of odontomas associated to impacted teeth, the teeth should be preserved in wait of spontaneous eruption, or alternatively fenestration followed by orthodontic traction is indicated. Regular follow-up period is crucial to evaluate the prognosis of these teeth.Öğe Does watching a video on third molar surgery increase patients' anxiety level?(Elsevier Science Inc, 2015) Kazancıoğlu, Hakkı Oğuz; Tek, Mustafa; Ezirganlı, Şeref; Demirtaş, NihatObjective. To identify the effects of watching live taping of third molar removal on patients' anxiety levels before and after extraction. Study Design. This study was based on a prospective, cross-sectional, observational investigation of the different patient education techniques about the effect of third molar removal on patients' anxiety level. A total of 333 patients were randomized into three groups: two study groups (for group 1, basic information was given verbally; for group 2, which was the study group, basic information was given verbally and through a movie on third molar extraction); and a control group (basic information was given verbally; it did not include information on operative procedures and recovery). Anxiety levels were assessed by using the Dental Anxiety Scale (DAS) and the Spielberger State-Trait Anxiety Inventory (STAI). Pain was assessed with a visual analog scale. Statistical analysis was performed with SPSS 16.0. Results. Group 2 patients were significantly more anxious before the surgical procedure, and the most significant decreases in DAS and STAI scores were observed in that group. The age, surgery time, and education level were not correlated with anxiety or pain levels; however, female patients had high levels of anxiety (P < .05). Conclusion. Preoperative multimedia information increases the anxiety of patients undergoing third molar surgery.Öğe THE EFFECT OF IMPLANT THERAPY ON MAXIMUM BITE FORCE IN EDENTULOUS ELDERLY PATIENTS: AN IN VIVO STUDY(Gunes Kitabevi Ltd Sti, 2015) Sener, Ismail; Aslan, M. Ali; Tek, Mustafa; Bereket, Cihan; Arici, Selim; Sato, ShuichiIntroduction: The purpose of the present study was to compare the bite force differences between conventional complete denture prostheses and implant retained overdentures. Materials and Method: The study group consisted of 15 complete denture patients. Three months after insertion of conventional dentures, the first bite force measurements were made with a Dental Prescale sheet (Fuji Film, Tokyo). After 5 and 7 weeks, two implants were placed in the mandibular symphysis region. Three months after implant surgery, implant retained overdentures were fabricated. Three months after the insertion of implant retained overdentures, a second set of bite force measurements was made and the values were recorded. Bite forces were compared between conventional complete dentures and implant retained overdentures and the chewing satisfaction obtained from patients in both groups was measured using visual analogue scale. All results were evaluated statistically using a paired t-test and values of p<0.05 were considered as statistically significant. Results: Bite forces and chewing satisfaction increased in all patients after the implant retained overdenture insertion. The mean bite force values before and after implant therapy were found 194.03 +/- 95.08 Newton and 302.91 +/- 119.84 Newton respectively. According to the paired t-test, a statistically significant difference were found in bite forces and chewing satisfaction before and after implant therapy (p<0.05). Conclusions: The present study showed increased bite forces and chewing satisfaction after insertion of implant retained overdentures.Öğe The effect of implant therapy on maximum bite force in edentulous elderly patients: An in vivo study(2015) Şener, İsmail; Aslan, M. Ali; Tek, Mustafa; Bereket, Cihan; Arıcı, SelimIntroduction: The purpose of the present study was to compare the bite force differencesbetween conventional complete denture prostheses and implant retained overdentures. Materials and Method: The study group consisted of 15 complete denture patients. Three months after insertion of conventional dentures, the first bite force measurements were madewith a Dental Prescale sheet (Fuji Film, Tokyo). After 5 and 7 weeks, two implants were placedin the mandibular symphysis region. Three months after implant surgery, implant retained overdentures were fabricated. Three months after the insertion of implant retained overdentures, asecond set of bite force measurements was made and the values were recorded. Bite forces were compared between conventional complete dentures and implant retained overdentures andthe chewing satisfaction obtained from patients in both groups was measured using visual analogue scale. All results were evaluated statistically using a paired t-test and values of p<0.05 were considered as statistically significant.Results: Bite forces and chewing satisfaction increased in all patients after the implant retained overdenture insertion. The mean bite force values before and after implant therapy were found 194.03 ± 95.08 Newton and 302.91 ± 119.84 Newton respectively. According to the paired ttest, a statistically significant difference were found in bite forces and chewing satisfaction before and after implant therapy (p<0.05). Conclusions: The present study showed increased bite forces and chewing satisfaction after insertion of implant retained overdentures.Öğe Effects of different local haemostatic agents on facial swelling after the third molar surgery(2015) Şener, İsmail; Metin, Murat; Bereket, Mehmet Cihan; Tek, Mustafa; Arıcı, SelimIt was aimed to investigate the effects of three different local haemostatic agents (oxidized regenerated cellulose, gelatin sponge and collagen sponge) on the facial swelling after surgical removal of impacted the third mandibular molar teeth, in this study. Sixty-six healthy patients (mean age, 21.21±3.14 years) requiring bilateral impacted third molar extractions were included in this double-blind, randomized, controlled clinical study. All teeth were removed bilaterally in the same operation by one surgeon. The left side of the mandible served as the test side for local haemostasis and the right side as the control side in all patients. After removal, the primary closure of surgical wound was provided with silk sutures, in the control side. One of the absorbable haemostatic agents, oxidized regenerated cellulose (ORC), gelatin sponge (GS) and collagen sponge (CS) was placed in the extraction cavities following gauze packing for 5 minutes to prevent bleeding and after that the wound was sutured. Data was collected regarding the operating time, mouth opening, and facial swelling. Facial swelling was measured by "point counting technique" on standard posteroanterior skull radiographs. The comparisons of differences belonging to ORC, GS and CS applications on preoperative and postoperative edema showed that the differences were not statistically significant according to analysis of variance (ANOVA) (p>0.05). This study has shown that the haemostatic local agents do not have any significant effect in the facial edema.Öğe Effects of energy drinks on serum VEGF and bFGF levels during wound healing(Carbone Editore, 2015) Toptaş, Orçun; Tek, Mustafa; Akkaş, İsmail; Kazancıoğlu, Hakkı Oğuz; Tosun, Mehmet; Özan, FatihIntroduction: Energy drinks consist of many substances like caffeine, taurine, sucrose/glucose, vitamins and some herbal supplements like ginseng, gingko biloba and guarana and are used by millions of people world-wide. The study aims to investigate the effect of energy drinks on blood vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) levels. Material and method: Thirty male adult Wistar albino rats were randomly assigned to two groups, an experimental group (EG) and the control group (CG). The Red Bull (3.57 mL/kg/day equivalent to a person weighing 70 kg consuming 250 mL per day) was given by oral gavage to the EG and the same volume of water was given by oral gavage to CG. The full thickness 5 cm diameter skin incisions were performed on the back of the rats. The blood samples were taken from the rats (n=5 in each group) on the 3rd, 7th and 14th days of the experiment. The biochemical blood analysis was performed at the end of the experiment. Results: The 3rd day, mean VEGF values of EG and CO were statistically different. Similarly, on the 14th day, mean bFGF values of EG and CG were statistically different. On the 7th day, there were no statistically differences between mean VEGF and bFGF values of EG and CG. Discussion: The ingredients of energy drinks may affect the wound healing positively or negatively with many mechanisms described in literature. Our results confirmed that energy drinks may accelerate angiogenesis in early and late stages of the proliferation phase of wound healing. Further investigations may reveal more reliable results.Öğe Effects of energy drinks on soft tissue healing(Lippincott Williams & Wilkins, 2014) Tek, Mustafa; Toptaş, Orçun; Akkaş, İsmail; Kazancıoğlu, Hakkı Oğuz; Fırat, Tülin; Ezirganlı Şeref; Ozan, FatihThe aim of the present study was to investigate the effects of an energy drink (ED) on soft tissue wound healing in the rat model. Thirty-six male Wistar albino rats were randomly divided into 2 groups. A full-thickness paravertebral linear incision wound model was created. The experimental group (EG) received an ED (Red Bull), and the control group (CG) received water. Red Bull (3.57 mL/kg/d) was administered to the rats by the oral gavage method on the day before the skin incision and continued for 14 days. The rats were sacrificed (n = 6 in each group) on the 3rd, 7th, and 14th day of the study. Sections were obtained from excised linear wound healing site and stained with hematoxylin-eosin and Masson trichrome for morphological analysis. To assess angiogenesis on the sections, immunohistochemical studies were carried out using vascular endothelial growth factor antibody and alpha smooth muscle actin Ab-1. The breaking strength of the wound healing site was measured in Newtons using a tensiometer. Morphological analysis showed that collagen deposition in the wound areas was statistically higher in the EG compared with that of the CG at both the third and seventh days (P < 0.05). Re-epithelialization on healing sites in the EG was statistically higher than in the CG on the seventh day (P < 0.05). The results of the immunohistochemical studies indicated that the numbers of new blood vessels in the wound healing sites of the EG were significantly higher at the 7th and 14th days when compared with the CG (P < 0.05). The breaking strength of the wound healing sites was also significantly higher on the 7th and 14th days in the EG (P < 0.05). The results demonstrate that ED accelerates soft tissue wound healing and that its effect may be due to increased collagen deposition, re-epithelialization, and new blood vessel formation in the wound.Öğe The effects of nigella sativa seed extract on bone healing in an experimental model(Lippincott Williams & Wilkins, 2016) Ezirganlı, Şeref; Kazancıoğlu, Hakkı Oğuz; Özdemir, Hakan; İnan, Zeynep Deniz Şahin; Tek, MustafaThe purpose of this study was to histologically evaluate the effects on bone healing of nigella sativa seed extract applied on calvarial defects in an ovariectomized rat model. The study included 32 female rats weighing 280 to 310g with an average age of 3 months. A defect was created with a trephine burr on each rat calvarium. The rats were divided into 2 groups (control and study) of 8 animals each. All the defects were grafted with a gelatin sponge mixed with normal saline. In the study group, nigella sativa seed extract was applied systemically using an oro-gastric tube. Half of the animals in each group were sacrificed after 2 weeks, and the others after 4 weeks. In the control groups, the defects were not completely filled with regenerated bone. Osteoblast cells were observed more in the study groups. A higher rate of osteoclasts was determined in the control groups. In addition, the nigella sativa group had a statistically greater amount of bone formation than the others group at both 2 weeks and 4 weeks (P<0.05). The systemic application of nigella sativa seed extract demonstrated incredibly positive effects on enhanced bone healing in this experimental osteoporotic model.Öğe Effects of the topical hemostatic agent Ankaferd Blood Stopper on the incidence of alveolar osteitis after surgical removal of an impacted mandibular third molar(Wolters Kluwer Medknow Publications, 2014) Tek, Mustafa; Akkaş, İsmail; Toptaş, Orçun; Özan, Fatih; Şener, İsmailBackground: Alveolar osteitis (AO) is a commonly seen post-operative complication during the wound-healing period after permanent tooth extraction or surgical removal of impacted third molar teeth. Objectives: The aim of this clinical study was to evaluate the effects of administration of the topical hemostatic agent Ankaferd Blood Stopper (ABS) into the socket on AO formation after impacted mandibular third molar extraction. Patients and Methods: Bilaterally, 100 half-impacted mandibular third molars were extracted in 50 patients. Then, 1.0 mL ABS was administered to achieve hemostasis in one half of the sockets and as a control, the other half was irrigated with 1.0 mL physiological serum after surgery. Results: There was no statistically significant difference in terms of AO formation (P > 0.05) between the extraction sites. However, the postoperative pain in ABS administration sites was higher than in the other sites for the first 2 days after surgery (P < 0.05). Conclusions: The results showed that ABS administration did not increase the incidence of AO formation. Thus, ABS can be used safely for hemostasis after impacted mandibular third molar surgery.Öğe The effects of zoledronic acid on mandibular fracture healing in an osteoporotic model : a stereological study(Lippincott Williams & Wilkins, 2013) Şener, İsmail; Bereket, Cihan; Köşker, Hüseyin; Türer, Akif; Tek, MustafaThe aim of this study was to evaluate the effect of zoledronic acid (ZA) in the ovariectomized rat on mandibular fracture. Corpus osteotomies were performed on the mandible of ovariectomized rats. Miniplates were placed on these rats, which were randomly divided into 4 groups. After 7 days, groups 3 and 4 were injected with 0.1 mg/kg ZA. Groups 1 and 2 were control groups, so they were injected 0.1 mg/kg saline solution. Animals in groups 1 and 3 were killed at 4 weeks, whereas groups 2 and 4 were killed 8 weeks after operation. The new bone volume of the fracture gap was examined stereologically. Although the difference was not statistically significant compared with the other groups (groups 1 and 3), more bone formation was found in ZA-treated groups (groups 2 and 4) (P < 0.05).Öğe Intraosseous epidermoid cyst associated with impacted mandibular wisdom teeth: an uncommon entity(Journal of Clinical and Diagnostic Research, 2014) Toptaş, Orçun; Akkaş, İsmail; Tek, Mustafa; Ozan, Fatih; Boran, ÇetinEpidermoid and dermoid cysts of the jaws are seen rarely. The formation theories of the intraosseous epidermoid cyst (IEC) are not clear. The radiographic appearance is similar with unilocular cysts. Surgical enucleation is the suggested treatment method for epidermoid cysts. This case report presents bilateral mandibular intraosseous epidermoid cysts with impacted wisdom teeth which is the first documented case in the literature.Öğe Periapikal granulomların aerop ve anaerop mikrobiyolojik incelemesi(2012) Tek, Mustafa; Metin, Murat; Şener, İsmail; Bereket, Mehmet Cihan; Karadağ, AdilAmaç: Modern laboratuar teknikleri kullanarak periapikal granulomlardaki mikroorganizmaları tespit etmek ve güncel literatür ışığında tartışmaktır. Gereç ve Yöntem: 15’i erkek, 20’si kadın toplam 35 hastadan, apikal küretaj yöntemi ile periapikal granulom örnekleri alındı. Daha sonra, her bir örneğin aerop ve anaerop mikrobiyolojik kültürleri oluşturuldu. Sonuçlar istatistiksel olarak değerlendirildi. Bulgular: 35 klinik materyalin 11 tanesinden (% 31,42) mikroorganizma izole edildi. İzole edilen mikroorganizmaların yüzde sıklık sırası: Streptococcus sanguis (% 20), Streptococcus anginosus (% 13,3), Streptococcus constellatus (% 13,3), Streptococcus milleri (% 13,3), Propionibacterium acnes (% 6,6), Bacteroides capillosus (% 6,6), Staphylococcus xylosus (% 6,6), Actinomyces meyeri (% 6,6), Candida albicans (% 6,6) tır. Sonuç: İzole edilen mikroorganizmalar içerisinde en sık streptokok türü bakteriler olduğu belirlendi. Bu sonuçlara göre periapikal granulomların doğası gereği polimikrobiyal olabileceği gözlemlendi.Öğe The predominant bacteria isolated from radicular cysts(Bmc, 2013) Tek, Mustafa; Metin, Murat; Şener, İsmail; Bereket, Cihan; Tokaç, MuratPurpose: To detect predominant bacteria associated with radicular cysts and discuss in light of the literature. Material and methods: Clinical materials were obtained from 35 radicular cysts by aspiration. Cultures were made from clinical materials by modern laboratory techniques, they underwent microbiologic analysis. Results: The following are microorganisms isolated from cultures: Streptococcus milleri Group (SMG) (23.8%) [Streptococcus constellatus (19.1%) and Streptococcus anginosus (4.7%)], Streptococcus sanguis (14.3%), Streptococcus mitis (4.7%), Streptococcus cremoris (4.7%), Peptostreptococcus pevotii (4.7%), Prevotella buccae (4.7%), Prevotella intermedia (4.7%), Actinomyces meyeri (4.7%), Actinomyces viscosus (4.7%), Propionibacterium propionicum (4.7%), Bacteroides capillosus (4.7%), Staphylococcus hominis (4.7%), Rothia denticariosa (4.7%), Gemella haemolysans (4.7%), and Fusobacterium nucleatum (4.7%). Conclusions: Results of this study demonstrated that radicular cysts show a great variety of anaerobic and facultative anaerobic bacterial flora. It was observed that all isolated microorganisms were the types commonly found in oral flora. Although no specific microorganism was found, Streptococcus spp. bacteria (47.5%) - especially SMG (23.8%) - were predominantly found in the microorganisms isolated. Furthermore, radicular cysts might be polymicrobial originated. Although radicular cyst is an inflammatory cyst, some radicular cyst fluids might be sterile.Öğe Propolis accelerates the consolidation phase in distraction osteogenesis(Lippincott Williams & Wilkins, 2014) Bereket, Cihan; Özan, Fatih; Şener, İsmail; Tek, Mustafa; Altunkaynak, Berrin ZuhalWe evaluated the effect of propolis on new bone formation after distraction osteogenesis (DO). This study examined 3 groups: control group, P100, and P200. Rabbits underwent DO of the left mandible after an osteotomy between the first molar and the mental foramen. Bone mineral content and bone mineral density were evaluated using dual-energy x-ray absorption 1 and 4 weeks after the procedure. The volume of connective tissue and new bone and the number of capillaries were measured using stereologic analysis after the subjects were killed. Dual-energy x-ray absorption showed that the bone mineral content and bone mineral density were higher in the groups treated with propolis by week 4, and these parameters were higher in the P200 group. Stereologic analysis showed no significant differences in connective tissue volume and number of capillaries among the groups. New bone volume was lowest in the P200 group. We concluded that propolis accelerates bone formation and may shorten the consolidation phase with DO.Öğe Temporomandibular disorders in scuba divers during diving certification training programme(Istanbul Univ, Faculty Medicine, Publishing Office, 2012) Örtürk, Özmen; Tek, Mustafa; Seven, HüseyinObjective: The design of a diving regulator's mouth-piece is known to increase the risk of a temporomandibular disorder (TMD) in SCUBA divers. The total weight of a diving regulator is reflected directly on the temporomandibular joint (TMJ) causing articular and periarticular problems. In this study, the prevalence of TMD in SCUBA divers having a training for diving certification is investigated. We also aimed to determine the factors that lead to TMD, and clarify the observation that there is an increased incidence of TMD in inexperienced divers with an anxiety of diving training. Material and methods: The study was held in a period of 5.5 years, between 2006 and 2011. Ninety-seven divers were referred with the complaint of pain around the temporomandibular area. The divers were classified according to their experince levels. Symptoms and signs of TMD were noted and graded. Results: 14 divers were diagnosed with TMD. It was found that TMD was seen more frequently in inexperienced divers than in experienced divers (p=0.0434). The most prevalent symptom was an increased effort spent for holding the mouth-piece during a dive. TMJ tenderness and trigger point activation were the mostly seen physical signs. 13 divers had an improvement with therapy. Conclusion: The effort for stabilizing the mouth-piece of the second stage of a diving regulator is a recognized factor in TMD development. The training for diving certification causes an increase in the prevalence of TMD.Öğe Temporomandibular disorders in scuba divers-an increased risk during diving certification training(Lippincott Williams & Wilkins, 2012) Öztürk, Özmen; Tek, Mustafa; Seven, HüseyinThe design of a diving regulator's mouthpiece increases the risk of a temporomandibular disorder (TMD) in scuba divers. The total weight of a diving regulator is reflected directly on the temporomandibular joint, causing articular and periarticular disorders. In the current study, the prevalence of TMD in scuba divers triggered during diving certification training is investigated. We also aimed to determine the factors that lead to TMD during diving training and clarify the observation that there is an increased incidence of TMD in inexperienced divers. The study was held between 2006 and 2011. Ninety-seven divers were referred with the complaint of pain around temporomandibular area. The divers were classified according to their diving experience. Symptoms and signs of TMD were graded. Fourteen divers were diagnosed with TMD. Temporomandibular disorder was seen more frequently in inexperienced divers than in experienced divers (P = 0.0434). The most prevalent symptom was an increased effort for mouthpiece gripping. Temporomandibular joint tenderness and trigger point activation were the mostly seen physical signs. Thirteen divers had an improvement with therapy. The increased effort for stabilizing the mouthpiece is a recognized factor in TMD development. Attention must be paid to an association of scuba diving with TMDs, especially in inexperienced divers having a scuba certification training.
