Yazar "Savli, Haluk" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    A Preliminary Psychometric Evaluation of the Type D Personality Construct in Turkish Hemodialysis Patients
    (Yerkure Tanitim & Yayincilik Hizmetleri A S, 2012) Alcelik, Aytekin; Yildirim, Osman; Canan, Fatih; Eroglu, Mustafa; Aktas, Glali; Savli, Haluk
    Objective: Type D personality, which is defined by both negative affectivity (NA) and social inhibition (SI), is associated with adverse outcomes in cardiac patients. The validity and reliability of the Type D Scale (DS_14) have been confirmed in various countries, particularly among cardiac patients. The purpose of the present study was to cross-validate the DS_14 in Turkish hemodialysis patients. Method: One hundred one patients, who had received maintenance hemodialysis for more than 3 months at a center in north-west region of Turkey, completed the Turkish version of the DS_14. Hospital Anxiety and Depression Scale (HAD) was administered to establish discriminant validity. The DS_14 was re-administered 1 month after first administration in order to examine the stability of the DS_14 in 100 patients. Results: The two-factor structure of the DS_14 and the internal consistency of the NA (alpha = 0.82) and SI (alpha = 0.81) subscales were confirmed. Both NA and SI were found to correlate positively with anxiety and depression scores. The DS_14 was stable over a 1-month period (r = 0.84/0.78; p< 0.01). The prevalence of Type D personality was 27.7%. Type D individuals had significantly higher mean scores on anxiety (p<0.01) and depression (p<0.01) subscales of the HAD when compared with non-Type D individuals. Conclusion: Preliminary evidence suggests that the Turkish DS_14 is a valid and reliable tool for identifying Type D personality. Future studies are warranted to evaluate the utility of the scale in different groups of patients.
  • Küçük Resim Yok
    Öğe
    Primary hyperaldosteronism as a rare cause of hypokalemia
    (National Academy of Medical Science and Ministry of Health of Ukraine, 2020) Kurtkulagi, Ozge; Aktas, Gulali; Kocak, M. Zahid; Atak, Burcin M.; Duman, Tuba T.; Bilgin, Satilmis; Savli, Haluk
    Primary hyperaldosteronism (PHA) is a syndrome characterized by increased aldosterone release and suppressed renin-angiotensin cascade. Hypertension, alteration in potassium homeostasis, and target tissue damage are characteristic features of the disease. The importance of recognizing PHA is due to the fact that it has a very negative cardiovascular and renal effect which can result in death. In this case report, we present a patient with resistant hypokalemia whom consequently diagnosed with PHA. A 54-year-old female patient who was scheduled for operation due to congenital hip dislocation was found to have decreased serum potassium in her preoperative laboratory tests. Therefore, the patient was referred to the internal medicine outpatient clinic with a serum potassium value of 2.1 mmol/L. Her systolic and diastolic blood pressures were 150 and 90 mmHg, respectively. On electrocardiogram, prominent U waves were noted. Therefore, potassium replacement was initiated at once by intravenous route. The potassium value in spot urine was 12.4 mmol/L. A 24 hour urine collected and urinary potassium excretion in 24 hours of urine was detected as 15 mmol/L, which means transtubular potassium gradient was greater than 4 mmol/L. Since she was hypertensive during clinical follow up in the ward, hypertension along with hypokalemia raised the clinical suspicion of hyperaldosteronism. Serum aldosterone renin ratio was measured as 155 %. A computerized tomography scan revealed (22 × 16 mm) neoplasm which was suggestive of adrenal adenoma in the right adrenal gland. Cushing Syndrome was ruled out with a normal cortisol level and pheochromocytoma was ruled out by normal levels of metanephrine in the 24 hours of urine. Spironolactone 50 mg was initiated and serum potassium was raised to normal range. She scheduled for unilateral adrenalectomy and discharged with full recovery of hypokalemia. Since PHA has undesired cardiovascular and renal effects which may increase mortality and morbidity, establishing the diagnosis as soon as possible is crucial. Hypertensive patients with hypokalemia or adrenal incidentaloma or obstructive sleep apnea syndrome, resistant hypertensive subjects, patients with moderate or severe hypertension, and hypertensive patients with a family history of PHA should undergo screening for PHA. In conclusion, we suggest that PHA should be kept in mind in differential diagnosis of the patients with hypertension and hypokalemia. © 2020 National Academy of Medical Science and Ministry of Health of Ukraine. All rights reserved.