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    Biliary ascaris-induced obstructive jaundice: a case of acute abdomen
    (Turkish Assoc Trauma Emergency Surgery, 2009) Ozturk, Hayrettin; Ozturk, Hulya; Duran, Hatun; Otcu, Selcuk
    Ascaris lumbricoides is one of the most common helminthic diseases worldwide and it can cause various complications. The presence of this worm in the biliary tree, however, is a rare condition, especially in children. We describe a child with biliary ascariasis who was presenting clinical symptoms mimicking surgical acute abdomen. The diagnosis was made by ultrasound. The child was successfully treated with mebendazole and anti-spasmolytic. Biliary ascariasis should be added to the differential diagnosis of acute abdominal pain in patients, even in children, from endemic areas.
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    Differential expression of CD34, S100, and c-Kit in interstitial cells of Cajal in infantile hypertrophic pyloric stenosis - Immunochemical study
    (2009) Ozturk, Hulya; Ozturk, Hayrettin; Yilmaz, Fahri; Okur, Hanifi; Otcu, Selcuk; Dokucu, Ali Ihsan
    Background. The pathogenesis of infantile hypertrophic pyloric stenosis (IHPS) is poorly understood although many hypotheses have been proposed. Objectives. Assessment whether the differential expression of c-Kit, CD34, and S100 may be involved in the development of IHPS. Material and Methods. Specimens from 14 infants with IHPS and seven control subjects were immunohisto-chemically stained for c-Kit, CD34, and S 100. The numbers of CD34+, S 100+, and c-Kit+ cells in five random fields per specimen were compared via light microscopy (x200). Results. In normal pyloric tissue, specific and intense c-Kit immunoreactivity was observed in the muscle layers and moderate staining was observed around the myenteric plexus. In IHPS patients, c-Kit+ cells were either absent or markedly reduced around the myenteric plexus. In control and IHPS patients, CD34+ cells were not observed around the myenteric plexus. In the vascular endothelium, moderate CD34 staining was observed in specimens from control subjects, whereas intense staining was observed for IHPS patients. In normal pyloric tissue, moderate S 100 immunoreactivity was observed in the muscle layers and intense staining was observed in the myenteric plexus. In IHPS patients, few S100+ cells were observed in the pyloric muscle layers and S100 immunoreactivity decreased markedly around the myenteric plexus. Conclusions. These results suggest that the numbers of c-Kit+ and S100+ cells are markedly decreased in the pyloric muscle layers and around the myenteric plexus in IHPS patients. Thus a lack of c-Kit and S100, but not CD34, expression may be a critical factor in the pathogenesis of IHPS and may serve as a useful prognostic tool in the treatment of this disease. © Copyright by Wroclaw Medical University.
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    Extralobar Pulmonary Sequestration in a Neonate
    (Aves, 2014) Ozturk, Hulya; Goksugur, Sevil Bilir; Dagistan, Emine; Yilmaz, Fahri; Ozturk, Hayrettin
    Congenital pulmonary sequestration (CPS) is a type of thoracic malformation that may be represented as a solid or cystic mass composed of nonfunctioning primitive tissue. It does not interact with the tracheobronchial tree and has unusual systemic blood supply. Various congenital malformations may be presented with CPS. More than one-half of CPS cases are diagnosed in later childhood or even in adulthood. Neonates and infants are usually asymptomatic, and they are usually diagnosed due to the presence of other congenital anomalies. Here, we report a 5-day-old neonate who was admitted to our clinic with respiratory distress. CPS was diagnosed without any other malformation.