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Öğe Biliary ascaris-induced obstructive jaundice: a case of acute abdomen(Turkish Assoc Trauma Emergency Surgery, 2009) Ozturk, Hayrettin; Ozturk, Hulya; Duran, Hatun; Otcu, SelcukAscaris lumbricoides is one of the most common helminthic diseases worldwide and it can cause various complications. The presence of this worm in the biliary tree, however, is a rare condition, especially in children. We describe a child with biliary ascariasis who was presenting clinical symptoms mimicking surgical acute abdomen. The diagnosis was made by ultrasound. The child was successfully treated with mebendazole and anti-spasmolytic. Biliary ascariasis should be added to the differential diagnosis of acute abdominal pain in patients, even in children, from endemic areas.Öğe Continuous infusion of small-volume fluid resuscitation in the treatment of combined uncontrolled hemorrhagic shock and head injury(2007) Ozturk, Hayrettin; Yagmur, Yusuf; Tas, Askin; Topcu, Soykan; Orak, MuratObjective: To determine the effect of continuous limited fluid resuscitation on the hemodynamic response and survival in rats in a model of uncontrolled hemorrhage shock due to Massive Splenic Injury (MSI) and Head Injury (HI). Design: An experimental study. Place and Duration of Study: Dicle University Animal Research Laboratory, Turkey, between January and February 2005. Subjects and Methods: Seventy Sprague-Dawley rats were used in this study. Group 1 rats (n=10) was sham-operated. In group 2 (n=10), only Massive Splenic Injury (MSI) was performed and untreated. In group 3 (n=10), only head injury (HI) was performed and untreated. In group 4 (n=10), HI and MSI were performed and were untreated. In group 5 (n=10), HI and MSI were performed and 15 minutes later treated with 7.5% NaCl. In group 6 (n=10), HI and MSI were performed, and rats were treated with Ringer's Lactate (RL) solution. In group 7 (n=10), HI and MSI were performed, rats were treated with 0.9 % NaCl. In groups 2,4,5,6 and 7 midline incision was reopened and splenectomy was performed at 45 minutes. Results: In group 4 rats, Mean Arterial Pressure (MAP) was decreased from 104 ± 6.1 mmHg to 75 ± 19.5 mmHg at 15 minutes; heart rate decreased from 357 ± 24.9 beats/min to 321 ± 62.1 beats/min and hernatocrit decreased from 46 ± 1.3 % to 43 ± 2.5% (p<0.01). Similar early changes in MAP, heart rate and hematocrit were observed in groups 5, 6, and 7, at 15 minutes. At 45,60 and 120 minutes, in fluid resuscitated rats (group 5,6,7) MAP, heart rate and hematocrit values were measured higher than group 2 and 4 (p<0.01 for all). At 120 min, in group 6, hematocrit was higher than group 4, 5 and 7, in group 6, total blood loss after splenectomy was calculated at 20 ± 2.4% of blood volume and was the best value compared to other fluid resuscitated group 5 and 7 (28% and 27% of blood volume) (p<0.01). Mortality was lower in all fluid resuscitated groups when compared to group 3 and 4 (p<0.05). The median survival time was again higher in fluid resuscitated groups. Conclusion: Continuous infusion of 7.5% NaCl, RL and 0.9 % NaCl following uncontrolled hemorrhagic shock with massive splenic injury and combined head injury resulted in better survival and RL did not increase abdominal bleeding before splenectomy was performed.Öğe Differential expression of CD34, S100, and c-Kit in interstitial cells of Cajal in infantile hypertrophic pyloric stenosis - Immunochemical study(2009) Ozturk, Hulya; Ozturk, Hayrettin; Yilmaz, Fahri; Okur, Hanifi; Otcu, Selcuk; Dokucu, Ali IhsanBackground. The pathogenesis of infantile hypertrophic pyloric stenosis (IHPS) is poorly understood although many hypotheses have been proposed. Objectives. Assessment whether the differential expression of c-Kit, CD34, and S100 may be involved in the development of IHPS. Material and Methods. Specimens from 14 infants with IHPS and seven control subjects were immunohisto-chemically stained for c-Kit, CD34, and S 100. The numbers of CD34+, S 100+, and c-Kit+ cells in five random fields per specimen were compared via light microscopy (x200). Results. In normal pyloric tissue, specific and intense c-Kit immunoreactivity was observed in the muscle layers and moderate staining was observed around the myenteric plexus. In IHPS patients, c-Kit+ cells were either absent or markedly reduced around the myenteric plexus. In control and IHPS patients, CD34+ cells were not observed around the myenteric plexus. In the vascular endothelium, moderate CD34 staining was observed in specimens from control subjects, whereas intense staining was observed for IHPS patients. In normal pyloric tissue, moderate S 100 immunoreactivity was observed in the muscle layers and intense staining was observed in the myenteric plexus. In IHPS patients, few S100+ cells were observed in the pyloric muscle layers and S100 immunoreactivity decreased markedly around the myenteric plexus. Conclusions. These results suggest that the numbers of c-Kit+ and S100+ cells are markedly decreased in the pyloric muscle layers and around the myenteric plexus in IHPS patients. Thus a lack of c-Kit and S100, but not CD34, expression may be a critical factor in the pathogenesis of IHPS and may serve as a useful prognostic tool in the treatment of this disease. © Copyright by Wroclaw Medical University.Öğe Extralobar Pulmonary Sequestration in a Neonate(Aves, 2014) Ozturk, Hulya; Goksugur, Sevil Bilir; Dagistan, Emine; Yilmaz, Fahri; Ozturk, HayrettinCongenital pulmonary sequestration (CPS) is a type of thoracic malformation that may be represented as a solid or cystic mass composed of nonfunctioning primitive tissue. It does not interact with the tracheobronchial tree and has unusual systemic blood supply. Various congenital malformations may be presented with CPS. More than one-half of CPS cases are diagnosed in later childhood or even in adulthood. Neonates and infants are usually asymptomatic, and they are usually diagnosed due to the presence of other congenital anomalies. Here, we report a 5-day-old neonate who was admitted to our clinic with respiratory distress. CPS was diagnosed without any other malformation.Öğe Hydatid cysts in children: analysis of 49 cases(Aves, 2006) Ozturk, Hlya; Ozturk, Hayrettin; Otcu, Selcuk; Onen, Abdurrahman; Duran, HatunPurpose: In this study, we aimed to analyze the diagnostic and therapeutic features, morbidity and mortality of patients with hydatid disease. Material and methods: 49 children (24 boys and 25 girls) infected by Echinococcus granulosus had surgery for hydatid disease. All patients were evaluated for age, sex, admission time, symptoms at admission, diagnostic techniques, locations of cysts, treatment modalities, morbidity and mortality rate. Ultrasonography, computed tomography, Casoni and Weinberg tests proved the diagnosis. Albendazole treatment was given to 27 of the patients in postoperative period. Results: Mean ages of the patients were 10.5 years. The most common symptom on admission was abdominal pain. The most common localization of the cyst was liver in 33 patients (% 67). Hydatid cysts were treated by conventional open surgery or percutaneous drainage. The form of surgical treatment was capitonnage and total excision of the cyst; and drainage of the cyst cavity in 47 patients (96%). Percutaneous treatment was performed in 2 patients (4%). There were no deaths. Recurrence rate was 4% during the follow-up period of 24 months (range, 8-60 months). Conclusion: Surgical treatment is successful in the hydatic cysts. Additionally, the study confirms the endemic state of the hydatic disease in our region.Öğe A rare malformation of the alimentary tract, tailgut cyst: A case report(Universa Press, 2018) Ozturk, Hayrettin; Dagistan, E.Tailgut cyst (cystic hamartoma) is a rare congenital pathology that arises-from post-natal primitive gut remnants in the retrorectal-presacral space. Because of the rarity of the lesion and the variability of the anatomical position, its diagnosis and surgical treatment are often difficult. Complete surgical excision of the multilocular and multicystic process prevents recurrent draining sinuses and eliminates the possibility of malignant change. We describe a case in which a tailgut cyst localized in the retrorectal and presacral space was characterized by abscess, repeated urinary tract infection, and rectal pain. © 2018, Universa Press. All rights reserved.
