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Öğe Anophthalmia, cleft lip/palate, absent vomer bone, nystagmus, and mental-motor retardation(Alliance Communications Group Division Allen Press, 2008) Ozcelik, Derya; Saglam, Ibrahim; Silan, Fatma; Sezen, Guelbin; Uenveren, ToygarObjective: We report that a 4-year-old boy presented with right unilateral complete cleft lip and palate, right anophthalmos, left congenital nystagmus, absence of the vomer bone, mental-motor retardation, and normal lymphocyte karyotype (46, XY). Methods: For reconstruction of the deformities, we performed cleft lip repair by Millard's rotation-advancement technique and planned cleft palate repair. Conclusions: This combination of cleft lip and palate, anophthalmos, congenital nystagmus, absent vomer bone, and mental-motor retardation has not, to our knowledge, previously been described. We suggest that this represents either another case of the rare Fryns anophthalmia-plus syndrome or a new syndrome.Öğe HPV-related scrotal verrucous carcinoma and anal condyloma acuminatum(John Libbey Eurotext Ltd, 2009) Ozcelik, Derya; Unveren, Toygar; Comunoglu, Nil Uestuendag; Yildirim, Uemran; Gurol, Yesim; Senyuva, CemalÖğe The Importance of the Trigeminal Cardiac Reflex in Rhinoplasty Surgery(Lippincott Williams & Wilkins, 2015) Ozcelik, Derya; Toplu, Gaye; Turkseven, Arzu; Sezen, Gulbin; Ankarali, HandanBackground Trigeminocardiac reflex (TCR) consists of bradycardia or asystole along with hypotension and apnea coinciding with stimulation of the trigeminal nerve. During rhinoplasty procedures, we noticed that local anesthetic solution (LAS) application to the columellar area results in bradycardia. We planned to conduct a randomized prospective study on 47 patients undergoing rhinoplasty to demonstrate the characteristics of TCR arising from the columella. Method Local anesthetic solution containing 2% prilocaine with 1:80,000 adrenaline was applied under standard general anesthesia protocol. In group 1 (study group, n = 24), 2 mL of LAS was applied to the columella. In group 2 (control group, n = 23), 2 mL of LAS was applied to the nasal dorsum. In group 3 (control group, n = 20), after LAS was applied to nasal dorsum in group 2, we waited for 10 minutes. Then, 2 mL of LAS was applied to the columella. Here, recordings were taken for the columella. Heart rate (HR) and blood pressure (BP) were recorded just before needle insertion (baseline level), at the time of needle insertion (NIT) to the columella or dorsum, and after the 1st, 5th, 10th, 30th, and 60th seconds. Results Transient bradycardia (>= 20% drop in HR) was observed in 33% of the patients in group 1. Decrease in HR compared to the baseline level in group 1 was significantly greater than that of groups 2 and 3 at all times (P <= 0.05). Systolic BP in NIT and in 60th second in group 1, only in NIT in group 2 was significantly lower than that of baseline levels (P <= 0.05). Conclusions We concluded that stimulation of a sensory branch of the trigeminal nerve in the columellar area leads to TCR under general anesthesia by eliciting clinical hypotension with a drop in systolic BP and in HR of more than 20% compared to the baseline level. Knowing the existence of a certain TCR area will be helpful to the surgeon and anesthesiologist to exercise extra vigilance and to make continuous and meticulous monitoring of the electrocardiogram, HR, and BP during which the TCR may be precipitated such as local anesthetic infiltration to the columellar area in rhinoseptoplasty operations.Öğe PRIMER CUTANEOUS ACTINOMYCOSIS IN DIABETIC PATIENTS(Gunes Kitabevi Ltd Sti, 2011) Alagaoglu, Cihangir; Yildirim, Umran; Albayrak, Hulya; Goksugur, Nadir; Ozcelik, DeryaActinomycosis is a chronic suppurative granulomatous infection caused by gram positive bacterium. Enfection especially affects the head, neck, thorax and abdomen. Primary cutaneous involvement is uncommon and has an association with trauma and local ischemia. We present one such case of primary cutaneous actinomycosis on the elbow of a 68 year old man with diabetes and external trauma. This patient was admitted to our clinic with a 10-12cm size blue-purple plaque. Skin biopsy revealed the characteristic 'sulphur granules' of actinomycosis in the deep dermis After the diagnosis, initially he was treated with penisilin and cotrimaxazol with a little effect. Treatment was continued with amoksisilin and cotrimaxazol and he respond to this medical treatment partially. After this medical therapy skin graft operation was performed. Lesions relapsed six months later. Medical therapy was repeated and still continues.Öğe Vertical Mammaplasty for Gigantomastia(Springer, 2009) Ozcelik, Derya; Unveren, Toygar; Toplu, Gaye; Bilgen, Fatma; Iskender, Abdulkadir; Senyuva, CemalA 48-year-old female patient presented with gigantomastia. The sternal notch-nipple distance was 55 cm for the right breast and 50 cm for the left. Vertical mammaplasty based on the superior pedicle was performed. The resected tissue weighed 3400 g for the right breast and 2800 g for the left breast. The outcome was excellent with respect to symmetry, shape, size, residual scars, and sensitivity of the nipple-areola complex. Longer pedicles or larger resections were not found in the literature on vertical mammaplasty applications. In our opinion, by using the vertical mammaplasty technique in gigantomastia it is possible to achieve a well-projecting shape and preserve NAC sensitivity.
