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    Biliary ascaris-induced obstructive jaundice: a case of acute abdomen
    (Turkish Assoc Trauma Emergency Surgery, 2009) Ozturk, Hayrettin; Ozturk, Hulya; Duran, Hatun; Otcu, Selcuk
    Ascaris lumbricoides is one of the most common helminthic diseases worldwide and it can cause various complications. The presence of this worm in the biliary tree, however, is a rare condition, especially in children. We describe a child with biliary ascariasis who was presenting clinical symptoms mimicking surgical acute abdomen. The diagnosis was made by ultrasound. The child was successfully treated with mebendazole and anti-spasmolytic. Biliary ascariasis should be added to the differential diagnosis of acute abdominal pain in patients, even in children, from endemic areas.
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    Differential expression of CD34, S100, and c-Kit in interstitial cells of Cajal in infantile hypertrophic pyloric stenosis - Immunochemical study
    (2009) Ozturk, Hulya; Ozturk, Hayrettin; Yilmaz, Fahri; Okur, Hanifi; Otcu, Selcuk; Dokucu, Ali Ihsan
    Background. The pathogenesis of infantile hypertrophic pyloric stenosis (IHPS) is poorly understood although many hypotheses have been proposed. Objectives. Assessment whether the differential expression of c-Kit, CD34, and S100 may be involved in the development of IHPS. Material and Methods. Specimens from 14 infants with IHPS and seven control subjects were immunohisto-chemically stained for c-Kit, CD34, and S 100. The numbers of CD34+, S 100+, and c-Kit+ cells in five random fields per specimen were compared via light microscopy (x200). Results. In normal pyloric tissue, specific and intense c-Kit immunoreactivity was observed in the muscle layers and moderate staining was observed around the myenteric plexus. In IHPS patients, c-Kit+ cells were either absent or markedly reduced around the myenteric plexus. In control and IHPS patients, CD34+ cells were not observed around the myenteric plexus. In the vascular endothelium, moderate CD34 staining was observed in specimens from control subjects, whereas intense staining was observed for IHPS patients. In normal pyloric tissue, moderate S 100 immunoreactivity was observed in the muscle layers and intense staining was observed in the myenteric plexus. In IHPS patients, few S100+ cells were observed in the pyloric muscle layers and S100 immunoreactivity decreased markedly around the myenteric plexus. Conclusions. These results suggest that the numbers of c-Kit+ and S100+ cells are markedly decreased in the pyloric muscle layers and around the myenteric plexus in IHPS patients. Thus a lack of c-Kit and S100, but not CD34, expression may be a critical factor in the pathogenesis of IHPS and may serve as a useful prognostic tool in the treatment of this disease. © Copyright by Wroclaw Medical University.
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    Hydatid cysts in children: analysis of 49 cases
    (Aves, 2006) Ozturk, Hlya; Ozturk, Hayrettin; Otcu, Selcuk; Onen, Abdurrahman; Duran, Hatun
    Purpose: In this study, we aimed to analyze the diagnostic and therapeutic features, morbidity and mortality of patients with hydatid disease. Material and methods: 49 children (24 boys and 25 girls) infected by Echinococcus granulosus had surgery for hydatid disease. All patients were evaluated for age, sex, admission time, symptoms at admission, diagnostic techniques, locations of cysts, treatment modalities, morbidity and mortality rate. Ultrasonography, computed tomography, Casoni and Weinberg tests proved the diagnosis. Albendazole treatment was given to 27 of the patients in postoperative period. Results: Mean ages of the patients were 10.5 years. The most common symptom on admission was abdominal pain. The most common localization of the cyst was liver in 33 patients (% 67). Hydatid cysts were treated by conventional open surgery or percutaneous drainage. The form of surgical treatment was capitonnage and total excision of the cyst; and drainage of the cyst cavity in 47 patients (96%). Percutaneous treatment was performed in 2 patients (4%). There were no deaths. Recurrence rate was 4% during the follow-up period of 24 months (range, 8-60 months). Conclusion: Surgical treatment is successful in the hydatic cysts. Additionally, the study confirms the endemic state of the hydatic disease in our region.