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Öğe Current status of arterial revascularization for the treatment of critical limb ischemia in infrainguinal atherosclerotic disease(Thieme Medical Publ Inc, 2018) Yüksel, Ahmet; Velioğlu, Yusuf; Çayır, Mustafa Çağdaş; Kumtepe, Gencehan; Gürbüz, OrçunCritical limb ischemia (CLI) is the most severe form of peripheral arterial disease (PAD) that may result in limb loss and even death; thus, the fast and proper treatment should be employed as earlier as possible to prevent these catastrophic consequences. Arterial revascularization is almost always an indispensable treatment option for CLI. Although both endovascular and surgical revascularization procedures have an important role, nowadays, the hybrid revascularization as a combination of these revascularization procedures has also gained increasing popularity in the treatment of patients with CLI. This review provides an update on the arterial revascularization strategies for the treatment of CLI.Öğe Management of lymphoedema(Verlag Hans Huber Hogrefe Ag, 2016) Yüksel, Ahmet; Gürbüz, Orçun; Velioğlu, Yusuf; Kumtepe, Gencehan; Şenol, SefaLymphoedema is a common and progressive disease which causes deterioration of the quality of life of patients. It is divided into two groups: primary and secondary lymphoedema. Nowadays, the majority of patients with lymphoedema are associated with a malignancy or its treatment modalities, such as cancer surgery and radiation therapy. Accurate diagnosis and effective treatment are crucial for alleviating the symptoms, preventing progression and reducing the potential risks of lymphoedema. This report provides an overview of the management of lymphoedema.Öğe An overview and update of femorofemoral crossover bypass surgery as an extra-anatomic bypass procedure(Georg Thieme Verlag Kg, 2018) Yüksel, Ahmet; Çayır, Mustafa Çağdaş; Kumtepe, Gencehan; Velioğlu, Yusuf; Atlı, Fahri Hayri; Müdüroğlu, Ayhan; Gürbüz, OrçunFemorofemoral crossover bypass is a surgical arterial revascularization modality which is commonly performed for unilateral aortoiliac occlusive disease. It is primarily applied to patients with intermittent claudication or critical limb ischemia in whom underlying anatomic constraints rule out endovascular means of restoring in-line flow and those who do not qualify for anatomic reconstruction due to the comorbid conditions that preclude a more invasive open surgical approach. This surgical procedure may be also used as a complementary component of endovascular repair of abdominal aortic aneurysms when one aortoiliac arterial system is occluded to ensure exclusion of the aortic aneurysm. This review represents the current status of femorofemoral crossover bypass surgery as an extra-anatomic bypass procedure.Öğe Predictive value of neutrophil-lymphocyte ratio for long-term cardiovascular event following coronary artery bypass grafting(Soc Brasil Cirurgia Cardiovasc, 2020) Gürbüz, Orçun; Kumtepe, Gencehan; Özkan, Hakan; Karal, İlker Hasan; Velioğlu, Yusuf; Ercan, Abdulkadir; Yüksel, AhmetObjective: To investigate the predictive value of preoperative neutrophil-lymphocyte ratio (NLR) for long-term major adverse cardiac and cerebrovascular events (MACCE), which have not yet been well described, in patients undergoing coronary artery bypass grafting (CABG). Methods: The records of 751 consecutive patients who underwent elective CABG between January 2008 and January 2010 were retrospectively enrolled and stratified according to quartiles of preoperative NLR. At 7.8-year follow-up, MACCE was considered as an endpoint. Results: Overall MACCE was 11.6% of all cases. Long-term myocardial infarction, percutaneous coronary intervention, stroke and cardiovascular mortality were found associated with the upper NLR quartile (P<0.001, P<0.001, P=0.005, P<0.001, respectively). In multivariate analysis, NLR on admission remained an independent predictor of long-term MACCE (OR 1.087, 95% CI 1.026-1.151; P=0.004), in all EuroSCORE risk groups (P<0.001; P<0.001; P=0.029). The receiver operating characteristic (ROC) curve analyses revealed an NLR cut-off value of 4.32 predicting MACCE. Conclusion: NLR is a useful and readily available predictive marker of long-term MACCE following CABG, independent of the EuroSCORE.Öğe Predictive Value of QT Interval for Postoperative Atrial Fibrillation in Patients Undergoing Off-Pump Coronary Artery Bypass Surgery(Soc Brasil Cirurgia Cardiovasc, 2022) Kumtepe, Gencehan; Ucaroglu, Erhan RenanIntroduction: Postoperative atrial fibrillation (poAF) is a common complication of coronary artery bypass grafting, and its reasons are still the subject of research. The aim of this study was to evaluate whether QT interval is related to new onset of poAF occurrence.Methods: This study included 167 patients undergoing elective isolated off-pump coronary artery bypass grafting (OPCAB) surgery. Patients were divided into two groups as poAF (+) and poAF (-), according to the development of poAF, and the results of the measurements were compared between the groups.Results: PoAF was detected in 37 (22.1%) of 167 patients who underwent OPCAB surgery. When QT interval measurements were compared, preoperative and postoperative QT and corrected QT interval (QTc) values were significantly longer in the group with atrial fibrillation. Mean values of preoperative QT were 407.5 +/- 27.1 in the poAF (-) group vs. 438.5 +/- 48.5 in the poAF (+) group (P<0.001). Mean values of preoperative QTc were 419.1 +/- 14.5 in the poAF (-) group vs. 448.5 +/- 26.6 in the poAF (+) group (P<0.001). Mean values of postoperative QT were 416.3 +/- 48.3 in the poAF (-) group vs. 439.2 +/- 45.8 in the poAF (+) group (P=0.005). And mean values of postoperative QTc were 419.8 +/- 12.5 in the poAF (-) group vs. 452.0 +/- 23.3 in the poAF (+) group (P<0.001).Conclusion: QT interval measurement may be a new parameter in predicting poAF development after OPCAB surgery.
