Yazar "Kosif, Rengin" seçeneğine göre listele
Listeleniyor 1 - 20 / 20
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Assessment of multiple areas on magnetic resonance midsagittal brain images in multiple sclerosis patients(Academy of Medical Sciences of Croatica, 2017) Kosif, Rengin; Türkoğlu, Şule Aydın; Bolaç, Elif Sultan; Dağıstan, EmineThe aim of the study was to compare the first and last magnetic resonance images (MRIs) in patients diagnosed with multiple sclerosis (MS) with MRIs of normal subjects. We wanted to investigate the region initially involved in MS patients. In this retrospective study, midsagittal plane was explored on brain MRIs taken at the time when MS diagnosis was established and the last MRI was obtained following treatment for MS. Comparison was done between healthy subjects and patients diagnosed with MS. The measures included the area of corpus callosum, cerebrum, cerebellum, pons, bulbus, fourth ventricle and pituitary gland. As a result, while there was growth in the fourth ventricle area, there was shrinkage in the other areas in MS patients. In women, the tissues involved at the beginning of the disease were pituitary gland, cerebrum and bulbus, and in men corpus callosum and cerebrum. Atrophy was not time-dependent. Assessment of the correlation between the Expanded Disability Status Scale (EDDS) and atrophy revealed an increase in EDDS (disease progression) to be associated with a decrease in the area of cerebrum and corpus callosum in men, and an increase in the fourth ventricular area in women. In conclusion, we demonstrated that pituitary gland atrophy develops in the early stage of MS, especially in women. Additional studies are needed to investigate the phenomenon of early pituitary and bulbus atrophy in women versus late atrophy of these tissues in men. © 2017, Academy of Medical Sciences of Croatica. All rights reserved.Öğe Clonninger's temperament and character inventory profiles of anatomists: is there a relation with specialty choice?(Comenius Univ, 2016) Kosif, Rengin; Konuk, NumanCareer psychologists have argued that the career choice and personality interfere with each other. There have been lots of investigations aimed at seeking the relationships between career interests and personality characteristics. There is limited knowledge on personality profiles of the anatomists and on how they are related with their specialty choices. AIM: In this research we aimed to explore the relationship between personality and career interests of anatomists. METHOD: Out of 279 anatomists who had been asked to complete the survey via e-mail including three questionnaires, 79 (53 male, 26 female) responded in the present study. Personality was assessed using the Cloninger's Temperament and Character Inventory (TCI). The career interest was determined by Holland's Theme Codes. RESULTS: The order of high frequency Holland's Codes was as follows: social (44.3 %), realistic (35.4 %), investigative (27.8 %), conventional (19.0 %), artistic (7.6 %), and enterprising (5.1 %). With regard to temperament components of TCI was as follows: novelty seeking (mean=17.7 +/- 4.7), harm avoidance (mean=13.9 +/- 6.1), reward dependence (mean=13.2 +/- 3.4), and persistence (mean=5.4 +/- 2.1). Character profiles are as follows: self-directedness (mean=33.1 +/- 6.3), self-transcendence (mean=17.9 +/- 7.6), and cooperativeness (mean=30.6 +/- 5.9). According to the last questionnaire, the most important cause for choosing anatomy is the interest in anatomy since medical study time. CONCLUSION: These results in part support Holland's theory, which takes the career as a function of personality and the personality profiles of anatomists have affected the motivation to select their specialty choice partially (Tab. 3, Fig. 1, Ref. 10).Öğe Comparison of all hand digit length ratios in left - and righthanded individuals(2012) Kosif, Rengin; Diramali, MuratAmaç: Beyin hemisferlerinden bir tanesi daha baskındır ve hangi hemisferin daha baskın olduğunun bilinmesi bireysel aktivitelerin yönlendirilmesinde önemlidir. Bu çalışma sağlak ve solak kız ve erkek öğrencilerde parmak uzunluğu ve parmak uzunluklarının birbirlerine oranları arasındaki olası farklılıkları saptamak için yapıldı. Yöntem ve gereç: 1-5. parmak uzunlukları ölçüldü (D). Ardından tüm parmakların diğer parmaklara olan oranı hesaplandı (1D:2D, 1D:3D, 1D:4D, 1D:5D, 2D:3D, 2D:4D, 2D:5D, 3D:4D, 3D:5D ve 4D:5D). Bulgular: Erkeklerde parmak uzunlukları ve birbirlerine olan oranları arasında anlamlı fark bulunamadı. Solak kızlarda 5. parmak uzunluğu ve 2D:5D, 3D:5D, 4D: 5D oranları arasında istatistiksel olarak anlamlı fark vardı. Solak kızlarda bu oranlar sol ellerinde sağ ellerine göre daha küçüktü ve 5. parmağın solak kızlarda daha uzun olduğunu gösteriyordu. Sonuç: Bu sonuçlar solak kızların topu yakalamayı gerektiren sporlarda daha başarılı olabileceklerini göstermektedir ve sporcu seçiminde solak kızlarda bu kriterin göz önünde bulundurulması faydalı olacaktır.Öğe Comparison of all hand digit length ratios in left- and right-handed individuals(Tubitak Scientific & Technological Research Council Turkey, 2012) Kosif, Rengin; Diramali, MuratAim: To compare and detect possible differences between the digit length and digit length ratios in left- and right-handed female and male students. One of the cerebral hemispheres is dominant over the other. Knowing a person's dominant hemisphere cart be a useful guide in some personal activities. Materials and methods: Digit lengths (D) of the students were measured, followed by calculating the ratio of each digit to the others (1D:2D, 1DÖğe Comparison of all hand digit length ratios in left-and right-handed individuals(2012) Kosif, Rengin; Dıramalı, MuratAim: To compare and detect possible differences between the digit length and digit length ratios in left - and righthanded female and male students. One of the cerebral hemispheres is dominant over the other. Knowing a person’s dominant hemisphere can be a useful guide in some personal activities. Materials and methods: Digit lengths (D) of the students were measured, followed by calculating the ratio of each digit to the others (1D:2D, 1D:3D, 1D:4D, 1D:5D, 2D:3D, 2D:4D, 2D:5D, 3D:4D, 3D:5D, and 4D:5D). Results: In males, no significant difference was found between digit lengths and digit length ratios. Among left -handed females, the fifth digit length was significantly longer. The 2D:5D, 3D:5D, and 4D:5D ratios were significantly smaller in their left hands, which indicated that the fifth digit was longer in left -handed females. Conclusion: The results of this study suggest that left -handed women could be especially successful in sports that require grasping a ball. This criterion should be considered for left -handed women while selecting athletes.Öğe Comparison of cerebellar volume between subjects with bilateral congenital blindness and healthy individuals(Soc Chilena Anatomia, 2013) Kosif, Rengin; Şahin, Bünyamin; Gürel, SafiyeCerebellum regulates motor control and physical coordination. It is known that when eye and hand need to be worked in combination, cerebellum is active and it provides coordination between eye and hand. Cerebellar cortex atrophy appears with dismetry and saccadic eye movement. If there is no stimulant related to vision, how cerebellum is adopted under this circumstance? In order to explore this, 27 male and 16 female volunteers with bilateral congenital blindness were compared with 35 male and 33 female healthy volunteers in this study. MR images of cross-sectional sequential cerebellum of volunteers with 1.5 mm thickness were realized in coronal plane. The surface area of apparent cerebellum seen in cross-sections was calculated by using Onis (Ver. 2.1) programme. Surface area data obtained by systematic randomized sampling were converted to volume by Cavalieri method. Cerebellar volume of bilateral congenital blind male was 128.15 +/- 11.11 cm(3), and cerebellar volume of bilateral congenital blind female was 118.60 +/- 10.73 cm(3). Cerebellar volume for healthy men and women were 132.89 +/- 12.51 cm(3) and 125.97 +/- 10.78 cm(3), respectively. It was revealed that cerebellar volume for bilateral congenital blind men was smaller than that of healthy men, but this difference was not significant. On the other hand cerebellar volume of bilateral congenital blind women was significantly smaller than that of healthy women (p<0.05). No asymmetry was detected between right and left side of cerebellum in both bilateral congenital blind and healthy subjects.Öğe Distances of palmar flexion creases (Haustra Digiti) and digital formulae in right and left handed people(Soc Chilena Anatomia, 2015) Kosif, Rengin; Dıramalı, Murat; Sertel, SedaDigital flexion creases are one of the external anatomical landmarks in the hand. In this study, we measured and compared the distances between the digital skin creases (haustra digiti) in the fingers of right-handed and left-handed individuals. We also recorded the digital formulae. No significant difference was detected between left and right-handed females and left and right handed males on distance of skin creases (p>0.05). No difference was detected on haustra digiti of the right handed females their own hands. Females who use their left hand had a significantly longer (p=0.48) distal haustra digiti segment on their right second finger than that of their left hand. However, no significant difference was detected between male individuals on their left and right hand all haustra digiti segments. The rate of hand digital formulae of 3>4>2>5>1 was 78.12% in left-handed females, 66.7% in left-handed males, 54.54% in right-handed females, and 78.57% in right-handed males. Our study has contributed to the literature on the morphological asymmetry of left-handed females.Öğe Effect of foot anthropometric measurements on postural stability(2020) Meyvaci, Seda Sertel; Meyvaci, Turgut; Kosif, Rengin; Diramali, Murat; Ankarali, HandanAim: To examine the effect of foot anthropometric measurements and body sizes of young maleadults with normal posture on balance.Methods: In this study, the effect of body size and foot anthropometric measurements of 112 youngmale adults with normal posture on balance was investigated. The foot and body parameters of thecases were measured. The static and the dynamic balance tests were evaluated according to thedominant foot in each case. The parameters that affected balance were determined and the variableswere taken to the model. In addition, the significance levels that defined the effects of the propertiesexamined in relation with the balance were also calculated.Results: When the findings were evaluated, it was determined that the effect of the foot parametersother than the foot length, and the effect of 15 body parameters other than the biiliac diameter,trochanteric height, and right upper extremity length on balance performance was significant. Thebalance test performance was predicted with success ranging from 7.8% to 43% with the parametersincluded in the model.Conclusion: In this study, the fact that the relation between the foot anthropometric and bodydimensions and functional balance performances of young male adults was found to be significantshows that this relation must be considered in the creation of a normative database on balance, and inclinical studies that will be conducted on the subject.Öğe Evaluation of apertura piriformis and related cranial anatomical structures through computed tomography: Golden ratio(Via Medica, 2019) Meyvacı, Seda Sertel; Kosif, Rengin; Bamaç, Belgin; Hızal, Mustafa; Ankaralı, HandanBackground: The purpose of study was to evaluate normal morphometric measurements of piriform aperture (PA) by limiting the age range in genders to show the morphometry of the relevant and close proximal cranial structures; and also to investigate whether these are in compliance with the golden ratio. Materials and methods: Our study was performed on 83 (42 female, 41 male) multidetector computed tomography images obtained from patients. A total of 14 morphological measurements were performed including the height of PA, the width of PA and 12 cranial structures; and these measurements were evaluated for compliance with the golden ratio. The differences of 14 parameters between the genders and age groups, and also the interaction of these two factors were analysed. Results: In our morphometric study, significant difference between the genders was found in all measurements except for the distance between vertex and rhinion (V similar to Rh), between rhinion and right foramen supraorbitalis (Rh similar to FSOR), between rhinion and left FSO (Rh similar to FSOL), and the width of PA on the level between the right and left foramen infraorbitalis (PAW similar to FIO) with the difference valid for both age subgroups (p < 0.05). When the differences between the age subgroups were evaluated, there was significant difference only at the widest distance of cranium (CW; p = 0.008); and it was observed that the average has increased with age in both genders. When the golden ratio was examined, the ratio of the distance between anterior nasal spine and nasion to the height of piriform aperture (NSA similar to N:PAH) was found to be within the limits of the golden ratio in males (p = 0.074). No golden ratio has been found in females. Conclusions: In our study, significant differences were detected between genders in all parameters of PA and in some parameters of the close cranial structures in the age group we examined. The effect of age was detected only in the CW parameter, and the PA and close cranial structures were not affected. In our study, the averages of the morphometric measurements of 13 parameters of young adults were determined. The PA and surrounding cranial structures are important for the area and related surgical procedures; however, gender differences must be considered in this respect. In addition to this, in the PA, which is the anterior limit of the skeletal nose in males, the NSA similar to N:PAH ratio having the ideal golden ratio limits is valuable in aesthetical terms and due to its position of the PA in the face.Öğe Evaluation of the dental-gingival health in children with cerebral palsy in Zonguldak(2013) Kosif, Rengin; Günalp, Zeki; Öz, Zehra SafiAmaç: Bu çalışmada serebral palsi tanısı almış Zonguldak’ta yaşayan çocukların diş ve dişeti sağlığı prospektif bir çalışmayla değerlendirilmiştir. Materyal ve Metot: Araştırma amaçları doğrultusunda değişik yaş gruplarında serebral palsili 51 kız, 69 erkek toplam 120 çocuğun diş ve dişeti muayenesi yapılmıştır. Çürük, kayıp ve dolgu sayıları kaydedilmiş ve DMTF indeksleri hesaplanmıştır. Enamel defektleri, renkleri ve hipoplazi oranları araştırılmıştır. Diş etleri muayeneleri gingival indeks ile değerlendirilmiş ve ağız pH’ları incelenmiştir. Bulgular: DMTF indeksleri kız çocuklar için 6,08±3,79, erkek çocuklar için 6,22±3,43 bulunmuştur. Değişik tiplerde enamel defektleri kızlarda %82,67, erkeklerde %86,87 olarak hesaplanmıştır. Akut dişeti enfeksiyonu kızlarda %31,91, erkeklerde %22,72 oranında bulun-muştur. Hipoplazi kızlarda %46,80, erkeklerde %37,87 oranındadır. Ağız pH’sı kızlarda 7,66±0,54, erkeklerde 7,96±0,60 olarak tespit edilmiştir. Sonuç: Ailelerin serebral palsili çocuklarda diş sağlığına dikkat etmedikleri görülmüştür. Bu çocukların dişlerini fırçalamadaki yetersizlikleri göz önüne alınarak düzenli olarak diş hekimine götürülmeleri önerilmiştir.Öğe An Examination of Bacterial Contamination of Models Used in Anatomy Laboratories(Hindawi Limited, 2018) Kosif, Rengin; Avcıoğlu, FatmaBackground. Bacterial, viral, and parasitic transmission is a common issue involving items that are used in crowded places and are touched. In this study, it was aimed to identify the types of bacteria on models used in anatomy laboratories and the types of bacteria that contaminate students' hands. Methods. Swab samples were taken from 30 models used in the laboratory and from the dominant hands of 94 students prior to and after contact with the models and were examined in the microbiology laboratory. Results. Five types of bacteria were isolated from the anatomy models: coagulase-negative staphylococcus, staphylococcus aureus, bacillus spp., enterococcus spp., and escherichia coli. Coagulase-negative staphylococcus, staphylococcus aureus, and bacillus spp. were isolated from the hands of the students before the contact, and additionally, enterococcus spp. were isolated after the contact. The hands were not found to be contaminated with escherichia coli originating from the models, whereas enterococcus spp. were found to be transmitted to the hands after the contact. Conclusion. The necessity of washing hands before and after working on the models and the necessity of occasionally disinfecting the models have emerged. © 2018 Rengin Kosif and Fatma Avcioglu.Öğe Histopathological effects of aloe barbadensis and soybean oil on rat liver(Soc Chilena Anatomia, 2010) Kosif, Rengin; Yılmaz, Fahri; Evrendilek, Gülsün Akdemir; Dıramalı, MuratAloe Barbadensis, which is a species of Aloe Vera, is a popular plant used by the common people and in alternative medicine. This study aimed to analyze the effects of Aloe Barbadensis and soybean oil on liver. For this study Wistar Albino female rats were taken and divided into 3 equal groups; the first group was the control group wherein no treatment was applied, second group in which the dissolved form of A. barbadensis in the soybean oil was applied (25 mg/clay), and the third group which only soybean oil was applied (500 mg/day). Biopsy materials were taken from the lobus dexter of the livers of the rats and analyzed with light microscope after the necessary standard processing of histologic slides. Group I demonstrated normal structural characteristics of rat liver. In Group IT and Group III, we observed nuclear enlargement, mild increase in chromatin and hydropic degeneration and binucleation in some hepatocytes. Liver histology demonstrated congestion in portal veins, sinusoids and the central veins. Merely in Group III, portal venous congestion and in Group II sinusoidal congestion was evident parenchyma of the liver. Additionally in Group III liver histology demonstrated plasmocyte infiltration in portal areas. Our study showed that using soybean with Aloe Barbadensis is synergystic and increasing each others effects. However we didn't observe mononeuclear infiltrations in Group II, these show antinflammatory effects of Aloe Barbadensis. It is determined that, depending on the used dose of Aloe Barbadensis, the toxic effect can change. If Aloe Barbadensis used very high doses it can have toxic effect on hepatocytes.Öğe Investigation of the effects of aloe barbadensis on rat ovaries: A preliminary study(Mary Ann Liebert, Inc, 2009) Kosif, Rengin; Aktaş, R. GülhanEffects of Aloe barbadensis, a type of Aloe vera, on ovaries were investigated during pregnancy. A. vera gel, a commercial and nontherapeutic form of A. barbadensis, was used for this purpose. Three groups (one control and two test groups) of female Wistar albino rats with no prior births were studied. Group I was administered 25 mg (140 mg/kg) of A. barbadensis/day both orally and through gavage. A. barbadensis was contained in capsules with 500 mg of soybean oil; therefore Group II was administered 500 mg of soybean oil. Group III was the control group. All three groups were given normal food and water ad libitum. The substance had been administered for 20 days until birth. Ovaries were examined histologically. Vascular increase and the hyperemic form of ovary in the group administered A. barbadensis were notable. Decrease in primary follicle numbers, increase in secondary follicle numbers, and diminishment of secondary follicle diameters occurred in ovaries. The histological changes imply an angiogenesis effect of A. barbadensis and an effect like that of follicle-stimulating hormone in ovaries.Öğe Investigation of the relation between face anatomy and leadership personality trait: Sample of faculty of medicine students(Wolters Kluwer Medknow Publications, 2019) Baki, Tuğçe; Kosif, RenginObjective: The aim of this study has to investigate the relationship some facial dimensions with between leadership personality traits. Methods: 139 university students have participated in our study. Two face photos from the front and the profile have been taken with the digital camera and transferred to the computer. 21 measurements including face and ear distances have been performed. A 32-question questionnaire has been applied to the participants about leadership personality traits. Results: According to the results we obtained from statistical analysis, it has been determined that the upper face length in women has shown a very weak positive correlation with the human leadership trait. A very weak positive correlation has been determined between philtrum length and human leadership trait in women. A very weak positive correlation between philtrum length and charismatic leadership trait in women. A weak negative correlation between philtrum depth and human leadership trait has been found in women. When the correlation coefficients and significance levels between leadership traits and facial anatomic measurements in the men have been examined, no statistically significant results have been found. Conclusion: Upper face length, philtum length and depth in women may give information about leadership personality trait. We hope this result contribute to the different disciplines.Öğe KİŞİLİK ÖZELLİKLERİ İLE YÜZ ANATOMİSİ ARASINDAKİ İLİŞKİNİN ARAŞTIRILMASI(2019) Kosif, RenginAMAÇ: Yüzümüzdeki anatomik ölçümlerin kişilik özelliklerimiz hakkında fikir verip vermeyeceğini araştırmak amacıyla bu çalışma planlanmıştır.GEREÇ VE YÖNTEM: Bu çalışmaya 76 kız ve 75 erkek üniversite öğrencisi katılmıştır. Dijital fotoğraf makinesi ile önden ve profilden yüz fotoğrafları çekilerek, bilgisayar ortamına aktarılmıştır. AutoCAD 2008 photoshop programı ile fotoğraflar üzerinde morfometrik ölçümler yapılmıştır. Göz ve burun ile ilgili anatomik yapılar ve üç yüz yüksekliği ölçülmüştür.BULGULAR: Yapılan istatistiksel analiz sonucunda ulaştığımız sonuçlara göre, kızlarda burun yüksekliği ile dışadönüklük arasında zayıf negatif, burun yüksekliği ile sorumluluk bilinci arasında çok zayıf pozitif korelasyon, üst yüz uzunluğu ile olumsuz değerlilik arasında zayıf pozitif korelasyon, alt yüz uzunluğu ile gelişime açıklık arasında çok zayıf pozitif korelasyon, kaşlar arası mesafe ile olumsuz değerlilik arasında zayıf pozitif korelasyon, gözler arası mesafe ile geçimlilik-uyumluluk arasında zayıf negatif korelasyon bulguları anlamlıydı. Erkeklerde ise olumsuz değerlilik ile yüz genişliği arasında güçlü negatif korelasyon, duygusal tutarsızlık ile üst yüz uzunluğu arasında zayıf negatif korelasyon bulguları anlamlıydı.SONUÇ: Sonuçlarımıza göre bazı yüz ölçümleri kişilik özelliklerimiz hakkında bize fikir verebilmektedir.Öğe Microscopic examination of placenta of rats prenatally exposed to aloe barbadensis: a preliminary study(Soc Chilena Anatomia, 2008) Kosif, Rengin; Akta, Gülhan; Öztekin, AynureAloe barbadensis is the most widely used both commercially and therapeutic properties. It has been used for an array of ailments since ancient times as a medicinal plant. There are more than 360 different species of Aloe. Its products have been used in health foods for medical and preservative purposes. The objective of this study was to search the effects of Aloe barbadensis on the rat's placenta. Gel form of Aloe barbadensis is used in the study. It is commercial, preserved but otherwise untreated form of Aloe Barbadensis gel capsul. Female Wistar Albino rats were divided into three groups. Placenta specimens from each groups were processed for the microscopic examination. Trophoblastic giant cells and spongiotrophoblasts were decreased in number after Aloe barbadensis; trophoblastic giant cells which showed degenerative changes. The nuclei of these giant cells were going degeneration characterized by pyknosis and bizarrely shaped. Extracellular matrix production around the cells was increased, thicker and more irregular basal membrane like formation around the cells. Decreased and abnormal vessel formation in labyrinth area was clear and reduced functional capacity of the trophoblastic barier. The study shows that, in the presence of Aloe barbadensis, relevant alterations associated with a possible compensatory adjustment to maintain adequate metabolic exchange take place in the structure of placenta. Our results also demonstrated that the exposure to Aloe barbadensis during pregnancy not led to fetal growth retardation, fetal death, abortion or teratogenic effect.Öğe Morphometric measurements of the cranium in congenital bilateral blind males and females(Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2013) Kosif, Rengin; Sırmatel, Öcal; Canan, ArzuCranium dimensions differ according to racial, geopraphic, ethnic and nutritional factors. This study will shed light on the question: "Is there a difference in the cranial distances measured between congenital bilateral blind people and healthy individuals?" Nine anthropometric measures were performed on the brain MRI midsagittally obtained from male and female congenital bilateral blinds. The anthropometric measures taken included the glabella-opisthocranion, nasion-dorsum sellae, dorsum sellae- opisthocranion, nasion-basion, nasion-opisthion, basion-opisthion, prosthion-basion, basion-vertex and the clival angle. In addition, the supratentorial and infratentorial areas were calculated. Glabella-opisthocranion, nasion-dorsum sellae, nasion-basion, prosthion-basion and clival angle were found to be smaller in the congenital bilateral blind females compared to the healthy group, but these results were not statistically significant. Whereas, other measures out of the basion-opisthion were found to be smaller in the congenital bilateral blind males than in the healthy subjects. Of these results, the distance between glabella-opisthocranion, nasion-dorsum sellae and nasion-basion was significantly smaller compared to the measurements taken from the healthy male group. The infratentorial area was significantly smaller in congenital blind male subjects and the supratentorial area was significantly larger in congenital blind female subjects. This study has revealed that the cranium dimensions of congenital blind people are to different from normal individuals. The most significant difference was in the distance of the nasion-dorsum sellae. The region anterior to the basion and dorsum sellae was prominently smaller. The infratentorial area was significantly smaller in congenital blind male subjects and the supratentorial area was significantly larger in congenital blind female subjects. (C) 2013 Association of Basic Medical Sciences of FB&H. All rights reservedÖğe Possible healing effects of aloe barbadensis on nephrotoxicity induced by soybean oil in rats(2011) Kosif, Rengin; Aktaş, Renan Gülhan; Ok, ElvanAmaç: Bu çalışmada Aloe Barbadensis’in böbrek üzerine koruyucu etkilerinin araştırılması amaçlandı. Gereç ve Yöntemler: Wistar Albino cinsi 18 dişi sıçan kullanıldı. Sıçanlar 3 eşit gruba ayrıldı. Ratların sağ böbreklerinin korteka ve medulla'sından biyopsi materyalleri alınarak ışık mikroskobik düzeyde incelendi. Bulgular: Kontrol deneklerin böbreklerinden alınan biyopsi materyalleri incelendiğinde normal boyut ve yapıda Malpighi cisimcikleri gözlendi. Proksimal,distal tübüller ve medulla olağandı. Aloe barbandensis verilmiş grupta ise Malpighi cisimciklerinde belirgin bir farklılık görülmedi. Ancak proksimal tübüllerde değişen derecelerde vakuolizasyon ve sonuçta yapısal özelliklerini tamamen yitirmiş proksimal tübüller gözlendi. Distal tübüllerde ise nadiren vakuolizasyon görüldü. İnterstisyel alanda korteks ve medullada konjesyon vardı. Sadece soya yağının verildiği üçüncü grupta ise tüm glomerüllerde ve medullada belirgin konjesyon vardı. Proksimal tübüllerdeki değişiklikler de ikinci gruba göre daha yaygın ve şiddetli düzeyde idi. Sonuç: Bu sonuçlar bize Aloe barbadensis’in, soya yağının böbrek üzerine olan toksik etkilerini iyileştirici rolü olduğunu düşündürmektedir.Öğe Possible Healing Effects of Aloe Barbadensis on Nephrotoxicity Induced by Soybean Oil in Rats(Erciyes Univ Sch Medicine, 2011) Kosif, Rengin; Aktas, Ranan Gulhan; Ok, ElvenPurpose: This study aimed to analyze the effects of Aloe barbadensis on kidney. Material and Methods: Eighteen Wistar Albino female rats were used for the experiment. They were divided into 3 groups. Biopsy materials were taken from the right kidneys of the rats and were analyzed under the light microscope. Results: Biopsy materials, which were taken from the kidneys of the control subjects, revealed normal structural features of renal cortex and medulla. No distinctive difference was found in the Malpighi corpuscles in the group receiving Aloe Barbadensis. However, various degrees of vacuolization in the proximal tubules, and the complete loss of structural characteristics of proximal tubules were observed. Vacuolization was rarely seen in distal tubules. Congestion was clear in the medulla. In the third group receiving only soybean oil, a distinctive congestion was observed in all glomerulus and in the medulla. The detected pathologic changes were more common and severe in the third experiment group that received only soybean oil. Congestion in glomerulus was mostly observed in this group. Conclusion: These results lead us to consider that Aloe barbadensis plays a healing role against the toxic effects of soybean oil on the kidney.Öğe Umblikal kord morfometrisi ile fetal ve maternal parametreler arasındaki ilişkinin araştırılması(2010) Kosif, Rengin; Bayar, Ülkü; Başaran, Mustafa; Gezer, Şener; Kaçar, Dündar; Kıyan, AysuAmaç: Kordon çapı ve boyu ile fetal ve maternal parametreler arasındaki ilişkiyi postpartum dönemde incelemek. Materyal ve Metod: Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Hastanesinde doğum yapmış 202 kadının maternal, plasental ve yenidoğana ait parametreleri, daha önceden hazırlanmış formlara doldurularak prospektif olarak incelendi. Bulgular: Maternal BMI ile kordon boyu arasında negatif korelasyon bulundu (p=0.045, r= -0.130). Umbilikal kord çapı yenidoğan boy, kilo, BMI ve göğüs çevresi ile pozitif korelasyon gösteriyordu. Umbilikal kord uzunluğu ile 5. dakika Apgar skoru arasında pozitif korelasyon vardı. Umbilikal kord uzunluğu plasenta santral kalınlığıyla pozitif korelasyon gösteriyordu. Umbilikal kord çapı tüm plasenta boyutları ve 5. dakika Apgar skoru ile pozitif korelasyon gösteriyordu. Umbilikal kord çapı ile uzunluğu arasında negatif korelasyon vardı (p=0.00, r=-0.227). Tüm istatistik sonuçları istatistiksel olarak anlamlı fakat zayıf korelasyon değerlerine sahiptir. Umbilikal kord morfolojisinin değerlendirilmesi önemlidir çünkü özellikle umbilikal kord çapındaki değişiklikler yenidoğan boyutlarını etkileyebilmektedir.
