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Öğe Comparison of analgesic effects of pure bupivacaine and morphine added as bupivacaine adjuvant in USG guided adductor canal block following total knee arthroplasty(2020) Türkoğlu, Kübra; Yıldız, İsa; Özturan, Kutay Engin; Işık, Cengiz; Karagoz, İbrahim; Yoldaş, Hamit; Bilgi, MuratObjectives: Total knee arthroplasty (TKA) is an operation that causes severe postoperative pain. Adductor canal block (ACB) is separated from the other peripheral blocks as a method that can provide analgesia by sensory blockade only. The aim of this study was to compare the analgesic effect of morphine-bupivacaine with pure bupivacaine in USGguided ACB after TKA. Methods: Sixty patients aged between 40-80 years with ASA I-III physical status who were scheduled for TKA surgery in our hospital were included in this prospective randomized study. Patients were randomly divided into two groups as Group BM (bupivacaine+morphine) and Group B (bupivacaine) by closed envelope method, and then the groups were compared with each other. Results: In Group BM, compared to Group B, there was a significant decrease in visual analogue scale (VAS) values during rest and movement at 8th hour, 12-24 hours time zone analgesic consumption and additional analgesia usage. Conclusion: We conclude that the morphine added to bupivacaine in the adductor canal block reduces the VAS value at 8th hour and analgesic consumption.Öğe Comparison of effects of low and high flow desflurane anaesthesia on hemogram parameters(2019) Yoldaş, Hamit; Karagoz, İbrahim; Ekici, Mustafa Ayhan; Eş, Abdulhamit; Yıldız, İsa; Demirhan, Abdullah; Bilgi, MuratObjectives: To compare the effects of low and high flow desflurane anaesthesia on hemogram parameters in lower abdominal surgeries. Methods: Sixty female patients who underwent lower abdominal surgery under general anaesthetic were included in this prospective study. Patients were randomly divided into two groups, as Group I (low flow) and Group II (high flow), and then compared with each other according to their demographic features and hemogram parameters. Results: Groups were statistically similar, and there were no significant differences in terms of demographic data between the groups (p>0.05). The comparisons of hemogram parameters within the groups showed that there were significant differences in plateletcrit, platelet-lymphocyte ratio and neutrophil-lymphocyte ratio values in Group I (p<0.05). The comparisons of hemogram parameters within Group II showed a statistically significance in plateletcrit and platelet-lymphocyte ratio values. A statistically significant difference was found for red cell distribution width, neutrophil- lymphocyte ratio, platelet-lymphocyte ratio and plateletcrit values between groups for the pre-operative and post-operative values of hemogram parameters (p<0.05). Conclusion: Our study showed that the administration of low flow anaesthesia led to a positive effect on the inflammatory response by lowering neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and red cell distribution width values, in comparison to high flow anaesthesia.