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    A case with adult still's disease who was treated with indomethacin and review of treatment approaches
    (2005) Şahin, Özlem; Karabay, Oǧuz; Parlak, Ali Haydar; Tamer, Ali
    Adult Still's disease (ADS) is a rare condition, usually presenting with high fever accompanied by systemic manifestations. Non steroid anti inflammatory drugs (NSAID) and steroids are used for first-line therapy. In patients that are nonresponsive to this therapy or those that require high dose steroid, disease-modifying antirheumatic drugs such as methotrexate (MTX), gold salts, cyclophosphamide, cyclosporine- A and azathioprine (AZA) can be used. The efficacy of interleukin 1 (IL -1) inhibitors and tumor necrosis factor-alpha (TNF alpha) blockers in chronic inflammatory disease like rheumatoid arthritis, ankylosing spondylitis and juvenile chronic arthritis is pointed. Recently studies show that these agents can be used successfully also in the patients who are resistent for conventional therapy. Here, it is aimed to investigate the new and conventional treatment approaches of ASD in the light of literature via presentation of a 51 year old female case with ASD that was treated with indomethacin.
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    Eritrocyt sedimantation rate
    (2006) Vardi, Şeref; Karabay, Oǧuz
    The ESR is an old, inexpensive, yet still widely used test. The test has a role in rheumatoid arthritis, temporal arteritis, polymyalgia rheumatica and myeloma. It may have an additional role in follow-up of patients with otitis media, osteomyelitis, sickle cell disease, HIV, pelvic inflammatory disease, intravenous drug users, prostate cancer and stroke. The ESR, however, should only be used as a guide. The clinician, when ordering an ESR, should realize that this test is only one parameter that could be helpful in the diagnosis and follow-up of certain inflammatory conditions and also have an important prognostic role in noninflammatory conditions such as prostate cancer, stroke. Thus, we continue to learn about this old yet still important test even today. We present a summary of clinical usefulness of the ESR through out of this review article.