Yazar "Karabay, O" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim Yok
    Öğe
    Efficacy of throat gargling for detection of group a beta-hemolytic streptococcus
    (Natl Inst Infectious Diseases, 2005) Karabay, O; Ekerbicer, H; Yilmaz, F
    The purpose of our study was to investigate the suitability of throat gargling with sterile saline as an alternative method to throat swabs for detection of group A beta-hemolytic streptococcus (GAS). Throat specimens were obtained from 601 cases belonging to different age groups. Sterile Dacron swabs and gargle residue were first streaked on the side of a 5% sheep blood agar plate to which a 0.04 U bacitracin disk bad been applied, and then 1.25 mg trimethoprim and 23.75 mg sulphamethoxazole were added to the plate. After incubation, beta-hemolytic colonies were classified serologically by latex agglutination. GAS was detected in both throat swabs and throat gargle specimens in 49 cases, but GAS was also detected in 12 throat swabs from patients with culture-negative gargles and in 8 gargle specimens from subjects in whom throat swabs were culture negative. The strength of agreement was evaluated by calculating the kappa coefficient (K = 0.82, P = 0.000). The sensitivity, specificity, positive predictive value, and negative predictive value of throat gargle specimens were 80.3, 98.5, 85.9, and 97.8%, respectively. Although the conventional throat swab culture remains the gold standard, the throat gargle method is a quick, safe, and easy method for detection of GAS that serves as an effective alternative to throat swab culture.
  • Küçük Resim Yok
    Öğe
    Impaired immunity against tetanus in Type 2 Diabetes
    (Int Scientific Information, Inc, 2005) Tamer, A; Karabay, O; Ekerbicer, H; Tahtaci, M; Selam, B; Celebi, H
    Background: The aim of this study was to compare serum levels of tetanus antibody in diabetic patients over 50 years of age with those of age-and sex-matched non-diabetic controls. Material/Methods: The study population consisted of 115 type 2 diabetic patients and 115 age-and sex-matched nondiabetic patients. Serum levels of tetanus IgG were measured by a commercial ELISA kit, and levels over 0.1 IU/ml were considered protective. Results: Mean serum levels of tetanus antibody in the diabetic and control groups were 0.164 +/- 0.140 IU/ml vs. 0.374 +/- 0.534 IU/ml, respectively (p < 0.001). Mean serum levels of tetanus antibody in the diabetics vs. controls aged 50-64 years were 0.172 +/- 0.141 IU/ml vs. 0.568 +/- 0.653 IU/ml and in those >= 65 years 0.151 +/- 0.139 IU/ml vs. 0.154 +/- 0.193 IU/ml, respectively (p < 0.001, p=1.000). Among patients aged 50-64 years, 38 (55.9%) cases in the diabetic and 45 (73.8%) in the control group demonstrated protective levels of tetanus antibodies (p=0.034). Of patients >= 65 years, 24 (51.1%) cases in the diabetic and 22 (40.7%) in the control group had protective levels of tetanus antibodies (p=0.298). Conclusions: Serum levels of tetanus antibody decreased in diabetic patients older than 50 years of age, whereas this period of time is prolonged to 65 years in healthy individuals. All individuals over 65 years should be vaccinated against tetanus; however, vaccination over 50 years of age might be considered for diabetic patients.