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    Coexistence of COVID-19, Pseudomonas, and thoracic actinomycosis in a cystic bronchiectasis case
    (BMC, 2023) Afşin, Emine; Küçük, Furkan; Özçelik, Hüsna; Haktanır, Muhammed Yavuz
    Actinomycosis often leads to cervicofacial infections, but thoracic involvement may also occur. However, the development of empyema is rare. While being followed up with the diagnosis of asthma and bronchiectasis, our case was hospitalized for infected bronchiectasis. As empyema developed in the follow-up, the pleural effusion was drained by tube thoracostomy. Actinomycosis was diagnosed through pleural effusion cytology. Growth of Pseudomonas aeruginosa was observed in sputum culture, and SARS-CoV2 RT-PCR was also positive in nasopharyngeal sampling. Polymicrobial agents can often be detected in actinomycosis. Actinomycosis cases have also been reported in the post-COVID period. Our case is presented since it would be the first in the literature regarding the coexistence of COVID-19, Pseudomonas, and thoracic Actinomycosis (empyema).
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    Methanol Intoxication in the Differential Diagnosis of COVID-19
    (2022) Afşin, Emine; Küçük, Furkan; Kalfaoğlu, Melike Elif
    Although central nervous system findings are promi nent in methanol intoxication, the lungs are also affected. There have been several studies in literature describing autopsy-based lung findings, while there have been no clinical cases reported on to date. We present here a case identified radiologically as pul monary edema that was included in the differential diagnosis of COVID-19.
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    A rare cause of dysarthria: Legionnaires' disease
    (Taylor & Francis Ltd, 2023) Afşin, Emine; Küçük, Furkan; Yıldız, Serpil; Ersoy, Sadettin
    Purpose/Aim of the StudyA case admitted with dysarthria and syncope and hyperintense lesion in the splenium of the corpus callosum, diagnosed as Legionnaires' disease by detecting Legionella antigen in the urine, and recovered only with antibiotic treatment is presented because it is rare in the literature.Materials and MethodsWhen a 64-year-old female patient was admitted to the emergency department with complaints of sudden loss of consciousness and fainting at home, she had speech impairment, and her pulse oxygen saturation in room air was 88%. In the neurological examination, there was no pathological finding except dysarthria in the patient with no motor deficit. The patient had no respiratory complaints and had a recent travel history. In laboratory examinations, hyponatremia was detected with increased C-reactive protein and liver enzymes. Consolidation was observed in the lower right zone on chest computed tomography. Ampicillin + sulbactam (4x1 gr, intravenous) and clarithromycin (2 x 500 mg orally) were initiated. On cranial magnetic resonance, a hyperintense lesion was observed in the splenium of the corpus callosum in the oval T2 sequence. Legionella pneumophila serogroup 1 antigen in urine was reported as positive. On the fourth day of her hospitalization, the patient, whose CRP and liver enzyme values regressed, her hyponatremia improved, her pulse oxygen saturation increased to 92% in room air, and her speech became comprehensible, was discharged after oral antibiotic treatment was arranged. On the 12th day, the speech ability of the patient completely returned to normal.ConclusionLegionella infection should be suspected in the presence of pneumonia and corpus callosum splenium lesion.