Yazar "Inanir, Mehmet" seçeneğine göre listele

Listeleniyor 1 - 8 / 8
  • Küçük Resim Yok
    Öğe
    Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses
    (2021) Coşgun, Mehmet; Cosgun, Zeliha; Güneş, Yılmaz; Sincer, Isa; Erdal, Emrah; Mansiroğlu, Aslı; Inanir, Mehmet
    Objectives: Several risk scoring systems have been validated for cardiovascular risk prediction and prognosis. Periarterial adipose tissue intima media adventitia (PATIMA) index combining carotid intima media thickness (CIMT), carotid extra media thickness (CEMT), cardiac epicardial fat thickness (EFT), and body mass index (BMI) are related to coronary artery disease (CAD).Materials and Methods: One-hundred-twenty-four patients were categorized as low synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) (<22) (n=84) or high SYNTAX (?22) (n=40) score groups. Association of PATIMA index and its components with SYNTAX score were analyzed.Results: CIMT, CEMT, BMI, EFT, and PATIMA index were not significantly different between groups. SYNTAX score was not significantly correlated with traditional CVS risk factors (diabetes, hypertension, hyperlipidemia, smoking, age). There was a significant correlation between the PATIMA index and age (r=0.308, p=0.001) but not with other risk factors. Age was significantly correlated with CIMT (r=0.289, p=0.001) and EFT (r=0.208, p=0.02) but not with CEMT (r=0.091, p=0.313). There was a significant correlation between CIMT and CEMT (r=0.414, p<0.001) and between CIMT and EFT (r=0.267, p=0.004).Conclusion: We have found that the recently described PATIMA index and its components, CIMT, CEMT, and EFT are not associated with the severity of CAD assessed by the SYNTAX score. Furthermore, they have not correlated with classical risk factors apart from age.
  • Küçük Resim Yok
    Öğe
    Comparison of the effect of uric acid/albumin ratio on coronary slow flow with other inflammation-based markers
    (Future Medicine Ltd, 2024) Toprak, Kenan; Ozen, Kaya; Memioglu, Tolga; Inanir, Mehmet; Kaplangoray, Mustafa; Akyol, Selahattin; Tascanov, Mustafa B.
    Background: Many inflammation-based markers (IBMs) have been shown to be closely related to coronary slow flow (CSF), but the effect of the uric acid/albumin ratio (UAR) on CSF and its relationship with other IBMs are not clearly known. In this study, we aimed to compare the effects of UAR and other IBMs on CSF. Methods: After the exclusion criteria, 126 patients with CSF detected on coronary angiography and 126 subjects with normal coronary flow as the control group were included in the study. Results: UAR was determined as an independent predictor for CSF. In addition, the UAR was superior to other IBMs in detecting CSF (p < 0.05 for all). Conclusion: This study is the first to investigate the effect of UAR on CSF in comparison with other IBMs.
  • Küçük Resim Yok
    Öğe
    Diyabetik Hastalarda Nötrofil/Lenfosit Oranı ve Trombosit/ Lenfosit Oranı ile Koroner Yavaş Akım Arasındaki İlişki
    (2021) Eren, Hayati; Inanir, Mehmet
    Amaç: Koroner yavaş akım fenomeni, anjiyografik olarak koroner arterlerin normal olması ve aynı zamanda distal koroner arter yata? ğının kontrast madde ile doluşunun gecikmesi olarak tanımlanmıştır. Diabetes mellitus ve kronik inflamasyonun koroner yavaş akım ge? lişimine neden olduğu gösterilmiştir. inflamasyon belirteçleri olan nötrofil?lenfosit oranının ve trombosit?lenfosit oranının diyabetik has? talarda koroner yavaş akım ile ilişkisini değerlendirmeyi amaçladık. Gereç ve Yöntem: Koroner yavaş akım tespit edilen 112 diyabetik hasta ile 112 normal koroner arterlere sahip diyabet hastası kontrol gurubu olarak çalışmaya dahil edildi. Nötrofil?lenfosit oranı ve trombosit?lenfosit oranı değerleri gruplar arasında karşılaştırıldı ve koro? ner yavaş akım ile trombosit?lenfosit oranı ve nötrofil?lenfosit oranı arasındaki ilişkiyi araştırmak için regresyon analizi yapıldı. Bulgular: Diyabetik koroner yavaş akım olan hastalarda trombosit?lenfosit oranı ve nötrofil?lenfosit oranı değerleri anlamlı olarak daha yüksekti (p <0,001). Çok değişkenli lojistik regresyon analizinde, nötrofil?lenfosit oranı ve trombosit?lenfosit oranı diyabetik hastalarda koroner yavaş akım için bağımsız birer prediktör olduğunu bulduk. Sonuç: Bu çalışma, diyabetik hastalarda koroner yavaş akım ile trombosit?lenfosit oranı ve nötrofil?lenfosit oranı arasında bir ilişki ol? duğunu göstermiştir. Kesin mekanizma açıklanamasa da, bulgularımız diabetes mellituslu hastalarda koroner yavaş akım fizyopatoloji? sinde inflamasyonun olası rolünü desteklemektedir.
  • Küçük Resim Yok
    Öğe
    The Effect Of Ranolazine Treatment Administered Before Coronary Artery Bypass Surgery On Perioperative Myocardial Damage In Patients With Stable Angina Pectoris
    (2022) Yilmaz, Mehmet Fatih; Efe, Süleyman Çağan; Acar, Emrah; Geçtin, Çetin; Inanir, Mehmet; Karabay, Can Yücel; Izgi, Ibrahim Akın
    Objective:Ranolazineisapiperazinederivativethathasbeenapprovedasanantianginal agent.Itisprimarilyusedasasecondlineantianginalagentinstablecoronaryarterydisease.Thestudywasdesignedconsideringthattheactiveingredientranalozine,\rwhich has antiischemic effectsthrough ischemic sodiumchannels, can reduce ischemia in the perioperative period and reduce\rthe frequency of perioperative myocardialinfarction.\rMethods: The study included patients with stable angina pectoris who underwent coronary angiography between January\r1, 2015 and June 30, 2016 at Koşuyolu Training and Research Hospital and who were diagnosed with multi-vessel disease\ror LMCA disease, and then for whom the joint council of Cardiology-Cardiovascular Surgery made a decision in favor of\rcoronary artery bypass grafting.\rResults: The mean age was 61.2 ± 8.6 years in the ranolazine group, while the mean age of the patients receiving standard\rtherapy was 57.9 ± 8.8 years (p = 0.073).The EuroSCOREs of the patients before the operation which were used to predict\rintraoperative mortality were similar. Mean troponin value of Group 1 patients at 0 hour was 1.70 (1.13-2.77), while mean\rtroponin value of the patients in Group 2 at 0 hour was 2.76(1.69-6.20)(p=0,01).\rConclusion:In the presentstudy,the immediate postoperative troponin 0 valuewasfound to be lowerin the ranolazine group.\rThere was no statistical difference in terms of troponin valuesmeasured at 12 and 24 hours.In thisstudy,we showed that early\rmyocardial damage was significantly reduced with ranolazine treatment.
  • Küçük Resim Yok
    Öğe
    P-wave duration and dispersion in lone obesity
    (College of Physicians and Surgeons Pakistan, 2021) Cosgun, Mehmet; Sincer, Isa; Inanir, Mehmet; Erdal, Emrah; Mansiroglu, Asli Kurtar; Gunes, Yilmaz
    Objective: To assess P-wave duration and dispersion (PD) in morbidly obese young subjects who do not have co-associated atrial fibrillation (AF) risk factors, such as hypertension, diabetes, atrial enlargement and diastolic dysfunction. Study Design: An observational cross-sectional study. Place and Duration of Study: Bolu Abant Izzet Baysal University Medical Faculty, Turkey; and the study was conducted between October 2017 and June 2018. Methodology: P-wave duration and dispersions were determined on 12-lead surface ECG in 47 morbidly obese and 44 healthy weight subjects, aged between 21-40 years. Above mentioned risk factors were studied. The correlation between BMI, PD and Pmax were investigated by Pearson correlation analysis. Results: Average body mass index (BMI) of obese and control groups were 42.3 (8.5) vs. 19.5 (1.5) (P <0.001). Maximum P-wave duration [(Pmax), 105.3±9.8 vs. 95.6±8.5, p<0.001] and PD [27.6 (7.6) vs. 12.2(8.3), p<0.001] were statistically significantly prolonged in obese patients when compared to the normal weight group. BMI correlation with Pmax and PD (r=0.485; p<0.001 and r=0.620; p<0.001, respectively) were significant. Conclusion: Pmax and PD, which are potential electrocardiographic AF predictors, may increase in lone obese patients having no comorbidities. © 2021 College of Physicians and Surgeons Pakistan. All rights reserved.
  • Küçük Resim Yok
    Öğe
    Reply to Letter: HbA1c/C-Peptide Ratio is a Potential Biomarker Used to Predict No-Reflow Phenomenon in Patients With ST-Elevation Myocardial Infarction
    (Sage Publications Inc, 2024) Toprak, Kenan; Kaplangoray, Mustafa; Inanir, Mehmet; Dursun, Ayten; Tascanov, Mustafa Begenc; Altiparmak, Ibrahim Halil; Bicer, Asuman
  • Küçük Resim Yok
    Öğe
    SPECT myocardial perfusion imaging for the evaluation of left ventricular mechanical dyssynchrony in obese patients
    (Wiley, 2024) Caliskan, Billur; Inanir, Mehmet
    Objective: Left ventricular dyssynchrony (LVD), the loss of coordinated contraction in the left ventricle, is an early sign of heart failure. LVD can be assessed using phase analysis techniques with gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). This study aimed to investigate the impact of obesity on LVD through phase analysis. Methods: We retrospectively enrolled 152 obese patients and 80 age- and sex-matched nonobese patients who showed normal myocardial perfusion and normal left ventricular ejection fraction (LVEF) on MPI. Phase standard deviation (PSD) and phase histogram bandwidth (PBW), as phase analysis parameters, were compared between patients with and without obesity. Results: Although PSD values were within the normal range (cut-off value >23) for both groups, the PSD values of obese patients were higher than those of the nonobese (20.49 +/- 8.66 vs. 14.81 +/- 4.93; p < 0.05). PBW values of obese patients were statistically significantly higher than those of the nonobese (57.03 +/- 23.17 vs. 41.40 +/- 9.96; p < 0.05). The PBW values of obese patients exceeded the normal limits (cut-off value >49). A weak positive correlation was observed between body mass index (BMI) and PBW values in obese patients (r = 0.181, p < 0.05). In patients of normal weight, no correlations were found between BMI and phase analysis parameters. Conclusion: LVD may develop in obese patients, even when myocardial perfusion and ejection fraction are preserved. The use of phase analysis with gated SPECT could be an additional finding improving the early detection of left ventricular dyssynchrony in obese patients.
  • Küçük Resim Yok
    Öğe
    Transkateter aort kapak implantasyonu yapılan hastaların sonuçları: Tersiyerbir merkezin 2 yıllık deneyimi
    (2020) Acar, Emrah; Inanir, Mehmet; Kılıçgedik, Alev; Izci, Servet; Yılmaz, Mehmet Fatih; Karabağ, Turgut; Izgi, Ibrahim Akın
    Giriş ve Amaç: Bu çalışmada merkezimizde transkateter aortik kapak implantasyonu (TAVİ) uygulanan hastaların erken vegeç dönem klinik ve ekokardiyografik takip sonuçları değerlendirildi.Hastalar ve Yöntem: 2011-2013 yılları arasında kliniğimizde ciddi aort darlığı (AD) nedeni ile TAVİ uygulanan 48 hastanınerken ve geç dönem sonuçları değerlendirildi. Tüm hastalara transfemoral yaklaşım ile CoreValve biyoprotez kapakyerleştirildi ve hastalar 17,4±15,3 ay takip edildi.Bulgular: Hastaların (24’ü kadın, ortalama yaş 77,4±8,1) işlem öncesi ortalama aortic kapak alanı (AVA) 0,7±0,2 cm2, ortalamaaortik kapak gradiyenti (MnG) 55,4±19,8 mmHg, fonksiyonel sınıfı New York Kalp Cemiyeti (NYHA)’ne göre 2,5±0,4 iken, TAVİişlemini takiben AVA, MnG ve fonksiyonel sınıflamalarında anlamlı düzelme görüldü. İşlem başarısı %87,5 olup, hastalaraortalama 1,5±0,5 kapak implante edildi. 1 hastada kapak implantasyonu sonrası hemodinamiyi bozan ileri paravalvüler AYgeliştiği için cerrahi aort kapak replasmanı yapıldı. İşlemde 3 hastada AV tam blok, 2 hastada koroner obstrüksiyona bağlıventriküler taşikardi; işlem sonrası erken dönemde ise 3 hastada geçici iskemik atak, 2 hastada minör kanama gelişti. 3 hastaişlemde gelişen kalp tamponadı nedeniyle, 1 hasta işlem sonrası 28. gün enfeksiyon ve sepsis nedeniyle, 2 hasta kompleksventriküler artimiye bağlı kardiyak arrestten, 2 hasta da 1. ve 4. aylarda kalp dışı nedenlerden hayatını kaybetti. İşlemin 3 yıllıkyaşam süresi %75 bulundu.Sonuç: Cerrahi riski yüksek veya opere edilemeyecek olan semptomatik AD hastalarında, cerrahiye alternatif bir tedaviyöntemi olarak klinik pratiğe girmiş olan TAVİ işlemi, erken ve geç dönem sonuçları itibariyle başarılı ve güvenilir biryöntemdir.