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    Antiepileptic effects of Allium schoenoprasum L. in the acute epilepsy model in rats
    (Natl Inst Science Communication-Niscair, 2024) Zaqzouq, Dana; Him, Aydin; Guneser, Ramazan; Turker, Arzu
    Epilepsy is a chronic clinical disorder and does not have a rational treatment, which basically aims to prevent seizure activity. Therefore, developing new treatment strategies that can intervene in epileptogenesis will make important contribution to epilepsy treatment. In order to find new compounds and develop new treatment strategies, here, we explored the potential antiepileptic effects of Allium schoenoprasum L. commonly known as chives. Two different epilepsy models were used to study the potential antiepileptic effects of A. schoenoprasum L. The first epilepsy model was induced by intracortical injection of 500 IU penicillin. The second epilepsy model was induced by injecting pentylenetetrazol (PTZ) at the dose of 60 mg intraperitoneally (i.p.). In the penicillin model, the animals were given A. schoenoprasum L. extract (200 or 400 mg/kg i.p.) after penicillin was applied and electrocortical activity was recorded for 120 min. In the PTZ model, the animals were given A. schoenoprasum L. extract at doses of 200 or 400 mg/kg orally for 7 days, after which the PTZ was applied, and tonic-clonic seizures were video recorded. A. schoenoprasum L. did not significantly change either the spike frequency or amplitude in the penicillin epilepsy model. Although it did not change the seizure score in the PTZ epilepsy model it reduced the death rate and significantly decreased the tonic-clonic seizure duration. The result suggests that A. schoenoprasum L. may have antiepileptic effects when applied chronically.
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    Evaluation of Perceived Stress Level and Emotional Eating Behaviors of Sports College Students During COVID-19 Pandemic
    (2021) Güneşer, Ramazan; Him, Aydin
    Objective The aim of our study was to investigate the perceived stress level and emotional eating behaviors of sports college students during the COVID-19 pandemic. Materials and Methods This study was conducted on 122 volunteer students studying at the Faculty of Sports Sciences of Bolu Abant Izzet Baysal University. The data was collected online through the socio-demographic data form, the Perceived Stress Scale, and the Emotional Eating Scale. Results The perceived stress scale score average of the students was 28.93±7.54, with 37.7% (n=46) having a low stress level, 58.2% (n=71) having a moderate stress level and 4.1% (n=5) having a high stress level. There was no significant difference between the groups in terms of emotional eating behavior scores (p=0,132). Both perceived stress level scores (P=0.044) and emotional eating behavior scores (p=0.001) of female students were significantly higher compared to male students. Both perceived stress scale scores (p=0.002) and emotional eating behavior scores (p=0.029) of the students with BMI<25 were statistically higher compared to the students with BMI> 25. Conclusion COVID-19 pandemic had a number of negative effects on students' stress levels and emotional eating behaviors. It is thought that quarantine measures that is applied to prevent transmission and spread of the disease, concerns about the disease and school education may contribute to these negative effects. During COVID-19 pandemic it is important to keep the immune system strong by preventing mood changes and related emotional eating behavior.