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Öğe Acute volvulus of the right colon: a case report(Elsevier Science Bv, 2009) Hasdemir, Ahmet Oguz; Kordon, Ozgur; Cakmaz, Ridvan; Turkeli, Vildan; Col, CavitAcute volvulus of the right colon is an uncommon cause of intestinal obstruction and is rarely diagnosed correctly at the time of presentation. The aim of the study is to discuss the clinical features and management volvulus of right colon. We report a case in an 81-year-old man was referred from a primary care centre with a four-day history of abdominal pain, distension and vomiting. He had undergone left inguinal hernioraphy for incarseration before 5 days. An emergency laparotomy was performed. The caecum was grossly distended with several areas of gangrene, and lay in the left side of the abdomen in operation. Right colon had rotated in a counter-clockwise rotation. An extended right hemicolectomy was subsequently performed. The operative management of volvulus of the right colon remains controversial. A review of the literature, it appears that right hemicolectomy is the treatment of choice for volvulus of the right colon, as it avoids all risk of recurrence and mortality is lower than that obtained with conservative treatment.Öğe The Effect of an Intraperitoneal Injection of Melatonin on Serum Amylase Levels in Acute Pancreatitis(E S Burioni Ricerche Bibliografiche, 2009) Col, Cavit; Dinler, Kahraman; Hasdemir, Ahmet Oguz; Bugdayci, GulerContext Several experimental studies have been carried out to explain the physiopathological mechanisms and to introduce endocrinological, enzymatic, biochemical and histopathological changes in organisms during acute pancreatitis. Objective To evaluate the effect of an intraperitoneal injection of melatonin on serum amylase levels. Design Experimental acute pancreatitis was experimentally caused through pancreatic duct ligation in 20 Winstar Albino rats. The rats were then divided into two groups: control and melatonin groups. Intervention The serum amylase level was measured on the 7th day after acute pancreatitis had developed. In the melatonin group, an intraperitoneal injection of melatonin (20 mg/kg/day) was performed starting from the 2nd day after pancreatic duct ligation. Main outcome measure The levels of serum amylase were measured with an auto analyzer. Results It was found that the mean (+/- SD) level of serum amylase in the control group was 947 +/- 182 IU/mL while it was 358 +/- 177 IU/mL in the experimental group (P< 0.001). Conclusions The 20 mg/kg/day intraperitoneal injection of melatonin which was carried out for one week attenuated the serum amylase levels to a statistically significant degree. The researchers believe that intraperitoneal injections of melatonin decrease the severity of acute pancreatitis.Öğe THE EFFECTS OF INTRAPERITONEAL MELATONIN INJECTION AND PINEALECTOMY IN EXPERIMENTAL ACUTE PANCREATITIS(Istanbul Univ, Faculty Medicine, Publishing Office, 2009) Dinler, Kahraman; Hasdemir, Ahmet Oguz; Col, Cavit; Gunduz, Blent; Bugdayci, Gler; Kukner, AyselObjectives: In this study the aim was to evaluate the effects of on biochemical markers and histopathological findings of pancreas tissue of decreeasing and increasing serum melatonin levels in rats with had experimental acute pancreatitis. Materials and methods: This study was conducted three groups of Winstar Albino rats (ten animals in every group) that have experimental acute pancreatitis. First group was evaluated as control group. Surgical pinealectomy was applied in the second group and the source of endogen melatonin was (low melatonin levels group). Third group of rats injected with 0.1 ml daily intraperitoneal injection of 20 mg/ml melatonin solution for one week was high melatonin levels group. The effects of melatonin levels on acute pancreatitis were evaluated by comparing these group according to histopathologial results of polimorphonuclear leukocytes. infiltration, oedema, haemorrhagie, apoptosis, aciner cellular degeneration in pancreatic tissue and the levels of malonyledialdeyde (MDA), glutathione reductase (GSH), superoxyde dismutase (SOD), aspartate transaminase (AST), alanine transpherase (ALT), amylase, lactate dehydrogenase (LDH) and bilirubine. Results: We investigated that high melatonin levels has an decreasing effect on of polimorphonuclear leukocyte infiltration, oedema, haemorrhage, aciner cellular degeneration, apoptosis in pancreatic tissue, AST, LDH, bilirubine and MDA levels. Conclusion: As a conclusion exogenous melatonin may have a preventive effect on inflammatory process by reducing oxidative damage in pancreatic tissue.Öğe Gastric Volvulus Associated with Wandering Spleen in Adult: Case Report(Derman Medical Publ, 2012) Buyukasik, Oktay; Hasdemir, Ahmet Oguz; Kahramansoy, Nurettin; Col, Cavit; Erkol, HayriGastric volvulus associated with wandering spleen is a rare diagnosis in adult ages. So far, only two cases have been reported in the literature. 82 year old male patients admitted to emergency department with complaint of nausea, vomiting and constipation. Physical examination and computerize tomography detected a big solid mass with regular contour which is full filling abdominal left lower quadrant. Exploratory laparotomy revealed a wandering spleen in sizes of 13x13x15 cm in the mentioned region. The spleen which had two masses on was partially ischemic. The stomach had rotated through cardiopyloric axis due to long pedicle of the spleen and adhesions neighborhood to corpoantral junction. Thus gastric passage was partialy obstructed. Splenectomy and anterior gastropexy were applied. The patient was discharged in health at 6th day postoperatively.Öğe RANDOMIZED CLINICAL TRIAL OF STAPLED HEMORRHOIDOPEXY VERSUS FERGUSON HEMORRHOIDECTOMY(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2008) Buyukasik, Oktay; Hasdemir, Ahmet Oguz; Keskin, A. Ilker; Arikan, Bilal; Bulbul, SalihObjective: The purpose of this study was to compare stapled hemorrhoidopexy (SH) with that of the Ferguson hemorrhoidectomy (FH) for the surgical treatment of hemorrhoidal disease. Material and Methods: Fifthy patients with grade III or IV haemorrhoids were randomized to undergo either the SH (n=25) or FH (n=25). Operative time, length of hospital stay, postoperative pain, early and late complications, time to return to normal daily activities ( both professional and social) and recurrence were evaluated. Follow up was one year. Results: Operative time, postoperative pain, the time to return to normal activities and recurrence were significantly less for patients in SH group. In the FH group early complications were more frequent but not statistically significant and there were no statistically significant differences regarding the frequency of late complications. Conclusion: Provided further clinical trials confirm these findings, SH may become a future gold standard.
