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Öğe Changes in the size of breast lesions during menstrual cycle observed by ultrasound: An initial study(Scientific Publishers of India, 2017) Dagistan, Emine; Canan, Arzu; Halicioglu, Siddika; Cosgun, Zeliha; Gurel, SafiyePurpose: We aimed to evaluate changes in size of breast lesions during menstrual phases. Material and methods: In this prospective study, 46 women aged 18-35 years old who were referred to our radiology clinic for breast sonography and had cystic or solid breast lesions larger than 5 mm were enrolled to the study. Breast ultrasound (US) was performed at two different times; one within 5 days before and one within 5 days after menstrual bleeding. Anteroposterior and transverse length of the lesions were measured. Results: In total, 145 breast lesions were detected by US. Of these lesions, 6 were visualized in premenstrual phase but were not observed in postmenstrual phase. 6 lesions different were not visualized in premenstrual, but were detected in postmenstrual phase. One hundred and twenty-three lesions were visualized by US both in luteal and follicular phases. Conclusions: Timing of breast US might cause false results and unnecessary further investigations. Therefore, we suggest that breast US in women should be performed in follicular phase of the menstrual cycle. © 2017, Scientific Publishers of India. All Rights Reserved.Öğe A childhood secondary headache case associated with Langerhans cell histiocytosis(2023) Kilinç, Yasemin Baranoğlu; Daniş, Ayşegül; Halicioglu, SiddikaNeurological involvement is very rare in patients with a diagnosis of Langerhans Cell Histiocytosis (LCH). During the course of the disease, headache can also be seen in addition to systemic effects. A 6 years old girl was admitted to the hospital with only a headache without any systemic symptoms and was diagnosed with LCH. Magnetic resonance imaging showed a solid mass extending from the sphenoid bone corpus to the left great wing of the sphenoid, left orbital apex, left posterior ethmoid cells, left cavernous sinus, and dural space. The correct decision for neuroimaging in patients with headaches is very important in terms of mortality and morbidity. We wanted to share our patient’s case who was diagnosed with LCH by presenting only with headache without any other systemic finding, to remind that LCH may be a secondary cause of headache.Öğe Effect of Iodized contrast substances used in computed tomography examination on kidney apparent diffusion coefficient (ADC) value(2023) Gür, Seray Gizem; Halicioglu, Siddika; Tekçe, HikmetAim: In this prospective study, our goal is to evaluate the effect of iodine-based contrast agent on renal Apparent Diffusion Coefficient (ADC) before and after the contrast agent in patients with normal and abnormal Glomerulary Filtration Rate (GFR) values using computed tomography (CT) imaging. Methods: The patients who applied for CT examination at an age older than 40 years and met the inclusion criteria of patient and control groups were included. DWI was evaluated by two radiologist in the same session. The range of interest (ROI) was adjusted to be less than 1.5 cm².The Spearman correlation test was used for statistical analysis. Results: A total of 48 subjects (23 and 25 subjects for patient and control groups, respectively) with two DWI scans were included. ADC values were compared for both kidneys before and after the administration of the contrast agent and a significant decrease in post-ADC values was observed in the control group (right kidney pre-ADC: 2,11±0,17 x10?³, post-ADC 2,07±0,15 x10?³ mm²/s, p=0,016; left kidney pre-ADC: 2,11±0,17 x10?³ mm²/s, post-ADC 2,04±0,14 x10?³ mm²/s, p=0,011). However, there was no significant difference between the patient groups according to the administration of contrast agent (right kidney pre-ADC: 1,97±0,22 x10?³ mm²/s, post-ADC: 1,97±0,24 x10?³ mm²/s, p=0,95; left kidney pre-ADC: 1,96±0,23 x10?³ mm²/s, post-ADC: 1,98±0,22 x10?³ mm²/s, p=0,64). Moreover, pre-ADC values in the patient group were relatively low. Pre-ADC values in both groups for the right kidney were 1,97±0,22 x10?³ mm²/s and 2,11±0,17 x10?³ mm²/s, respectively (p=0,016). Pre ADC values in both groups for the left kidney were 1,96±0,23 x10?³ mm²/s and 2,11±0,17 x10?³ mm²/s, respectively (p=0,018). No significant differences in the post-ADC values were observed between the two groups. Conclusion: No decrease in ADC values was observed after the administration of iodine- based contrast agent in patients with a GFR less than 60, whereas there was a relatively high decrease in patients with normal GFR.Öğe A Rare Case Report: MOGAD with Optic Neuritis- without Spinal İnvolvement(2023) Turel, Canan Akünal; Halicioglu, SiddikaMOGAD (Myelin Oligodendrocyte Glycoprotein Antibody Disease) is caused by antibodies against the myelin oligodendrocyte glycoprotein (MOG) found on the surfaces of oligodendrocytes and its damage. MOGAD and Neuromyelitis Optica Spectrum Disorders (NMOSD) are very rare autoimmune inflammatory demyelinating diseases of the central nervous system that are often se en with joint involvement of the optic nerves and spinal cord. MOGAD can be confused with Multiple Sclerosis (MS) or NMOSD, which are more common in the community, due to its clinical presentations that may be similar and its characteristic to progress with habitual attacks. Although the clinical course of these three diseases is similar, their diagnosis and treatment are different; It is important to avoid diagnostic confusion, to make differential diagnosis of patients with other diseases and not to waste time for treatment, to prevent possible disability and disability. In addition, Optic Neuritis is an inflammatory disease of the optic nerve and is very common in patients with Multiple Sclerosis, and it can often be the first clinical presentation of the disease. However, being the first and early finding in other very rare demyelinating diseases can cause diagnostic confusion. In this article, we wanted to present the importance of optic neuritis, demyelinating diseases and differential diagnosis in a İnformed consent of the patient was obtaine d, 51-years-old female patient who had bilateral optic neuritis attacks at different times, in the light of the literature.
