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Öğe A Case of Methimazole Induced Leukocytoclastic Vasculitis(Galenos Yayincilik, 2005) Kanat, Mustafa; Goksugur, Nadir; Parlak, Ali HaydarAntineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis has been described frequently in patients treated with propylthiouracil (PTU). However, other antithyroid drugs, carbimazole and methimazole (MMI), rarely cause vasculitis. We report a case of MMI induced ANCA negative leukocytoclastic vasculitis.Öğe Extensive oral ulcerations(New Zealand Medical Assoc, 2006) Goksugur, Nadir; Yilmaz, FahrettinÖğe Halo Phenomenon With an Unusual Involvement: Bilateral Halo Nipple(Amer Medical Assoc, 2010) Goksugur, Nadir; Sereflican, Betul; Goksugur, Sevil BilirÖğe Hand, Foot, and Mouth Disease.(Massachusetts Medical Soc, 2010) Goksugur, Nadir; Goksugur, SevilÖğe A new computer-associated occupational skin disorder: Mousing callus(Mosby, Inc, 2006) Goksugur, Nadir; Cakici, HusamettinÖğe PRIMER CUTANEOUS ACTINOMYCOSIS IN DIABETIC PATIENTS(Gunes Kitabevi Ltd Sti, 2011) Alagaoglu, Cihangir; Yildirim, Umran; Albayrak, Hulya; Goksugur, Nadir; Ozcelik, DeryaActinomycosis is a chronic suppurative granulomatous infection caused by gram positive bacterium. Enfection especially affects the head, neck, thorax and abdomen. Primary cutaneous involvement is uncommon and has an association with trauma and local ischemia. We present one such case of primary cutaneous actinomycosis on the elbow of a 68 year old man with diabetes and external trauma. This patient was admitted to our clinic with a 10-12cm size blue-purple plaque. Skin biopsy revealed the characteristic 'sulphur granules' of actinomycosis in the deep dermis After the diagnosis, initially he was treated with penisilin and cotrimaxazol with a little effect. Treatment was continued with amoksisilin and cotrimaxazol and he respond to this medical treatment partially. After this medical therapy skin graft operation was performed. Lesions relapsed six months later. Medical therapy was repeated and still continues.Öğe Serum visfatin, adiponectin, and tumor necrosis factor alpha (TNF-?) levels in patients with psoriasis and their correlation with disease severity(Croatian Dermatovenerological Society, 2016) Sereflican, Betul; Goksugur, Nadir; Bugdayci, Guler; Polat, Mualla; Parlak, Ali HaydarPsoriasis is a chronic, autoimmune, and inflammatory disease of unknown etiology, characterized by T lymphocyte mediated keratinocyte proliferation. In recent years the relationship between psoriasis and adipose tissue cytokines has been reported. Psoriasis as a triggering factor for the immune and metabolic disorders can be associated with diabetes mellitus, abnormal lipid metabolism, and metabolic syndrome. In this study we assessed the adipose tissue cytokines visfatin, adiponectin, and tumor necrosis factor-? (TNF-?) levels in psoriasis patients and evaluated the relationship between disease severity and cytokines. The study included 42 patients with psoriasis and 42 healthy individuals. Visfatin, adiponectin, and TNF-? levels were measured in both the psoriasis and the control group. The disease severity index was assessed in psoriatic patients by means of PASI. The relationship between visfatin, adiponectin, TNF-?, PASI score, and obesity was evaluated. When serum TNF-?, adiponectin, and visfatin levels of the patient group were compared with those of the control group, the TNF-? levels were statistically higher (p = 0.00) and the adiponectin levels were statistically lower (p = 0.024). The visfatin levels were higher in the psoriatic patients compared to the control group, but this difference was not statistically significant (p = 0.73). The relationship between PASI-TNF-? and between PASI-adiponectin was statistically significant (p = 0.009 and p = 0.004). A positive correlation was observed between body mass index (BMI) and visfatin (p = 0.031). These results indicate that TNF-? and adiponectin play a part in psoriasis etiopathogenesis and can be used as parameters to evaluate the severity of the disease. However, the role of visfatin in psoriasis pathogenesis is unclear. Further clinical studies are needed to clarify the effect of visfatin in psoriatic patients. © 2016, Croatian Dermatovenerological Society. All rights reserved.Öğe Tularaemic cervical lymphadenopathy(New Zealand Medical Assoc, 2007) Karabay, Oguz; Yilmaz, Fahrettin; Gurcan, Saban; Goksugur, Nadir
