Yazar "Geyik, Mehmet Faruk" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    ERCP Sonrası Bakteriyemi ile Mortal Seyreden Klatskin Tümörü Olgusu
    (2015) Geyik, Mehmet Faruk; Kara, Ismail Hamdi; Ince, Nevin; Akkaş, Idris; Şen, Şeyda
    Klatskin tümörleri yada hiler kolanjiokarsinoma erken dönemde semptom vermemesi nedeniyle geç tanı almaktadır. Uzun dönem yaşam beklentisi oldukça düşüktür. Daha önceden obesite ve depresyon tanısı olan 83 yaşındaki bayan hasta, iki gün önce başlayan karın ağrısı, bulantı, sarılık şikâyetleriyle Düzce Üniversitesi Tıp Fakültesi Aile Hekimliği polikliniğine başvurdu. Hastanın Aile Hekimliği Polikliniğinde yapılan hepatobiliyer ultrasonografi incelenmesinde safra kesesi çapı 50 mm, koledok 14 mm ile distandü görülmüştür. Hasta Klinik-laboratuvar bulgularıyla Enfeksiyon Hastalıkları ve Gastroenteroloji Polikliniklerinde değerlendirildi. Endoskopik Retrograd Kolanjiografi (ERCP) yapılması için dış merkeze yönlendirildi. ERCP sonrası klinik durumu daha da ağırlaştıran bakteriyemi gelişmiştir. Bu olguda, klatskin tümörlü yaşlı hastada invazif tıbbi girişim üzerine eklenmiş bakteriyemik enfeksiyon tablosunun prognozu kötüleştirip mortaliteyi artırdığı irdelenmiştir.
  • Küçük Resim
    Öğe
    Intestinal ischemia, bacterial translocation, and oxygen free-radical production in abdominal compartment syndrome
    (Wroclaw Medical Univ, 2009) Yağmur, Yusuf; Öztürk, Hayrettin; Güloğlu, Cafer; Geyik, Mehmet Faruk; Öztürk, Hülya; Mete, Fatih
    Objectives. The aim of this experimental study was to evaluate the consequences of increased intra-abdominal pressure on the small bowel and whether this pressure creates intestinal ischemia leading to oxygen free-radical production and bacterial translocation. Material and Methods. Twenty Sprague-Dawley rats weighing 275-300 g were used. Group 1 rats (n = 10) were subjected to 20-mm Hg pneumoperitoneum pressure for 60 minutes. In group 2 rats (n = 10, controls) the intra-abdominal pressure was not increased. In all rats the following parameters were investigated: mean arterial pressure after carotid catheterization, histopathological examination of the intestinal mucosa evaluated with a scoring system, malondialdehyde production in the liver and small bowel, and bacterial translocation towards the mesenteric lymph nodes, liver, and spleen 24 hours after pneumoperitoneum deflation. Results. The mean arterial pressure exhibited no alterations. Histological analysis mainly showed extensive epithelial separations from the lamina propria down the sides of the villi and ulceration at the villus tips in the rats with increased intra-abdominal pressure. Bacterial translocation occurred to the mesenteric lymph nodes, spleen, and liver after 60 minutes of increased intra-abdominal pressure of 20 mm Hg (p < 0.05). Malondialdehyde increased in the liver and small bowel mucosa (p < 0.05 for both). Conclusions. Increased intra-abdominal pressure in rats leads to intestinal ischemia and mild histological changes in the small bowel and to oxygen free-radical production and bacterial translocation (Adv Clin Exp Med 2009, 18, 2, 115-120).
  • Küçük Resim
    Öğe
    Risk factors for multi-drug-resistant pseudomonas aeruginosa ınfections in a university hospital-a case control study
    (2016) Üstün, Cemal; Hoşoğlu, Salih; Geyik, Mehmet Faruk
    rpose: This study aims to determine the risk factors associated with multi-drug-resistant Pseudomonas aeruginosa (MDR-Pa) infections. Methods: A case control study was conducted at the Dicle University Hospital which is 1150-bed tertiary care teaching hospital in Diyarbakir, Turkey. The study cases were recruited from patients with nosocomial MDR-Pa infections. Two control cases were arranged to compare risk factors of MDR-Pa infections. One of the control groups was composed of patients with non-MDR-Pa infections and the other group with non-MDR Gram-negative bacterial infections except P. aeruginosa. Results: Overall, 225 patients were included in the study, 75 with MDR-Pa infections, 150 control cases (75 non-MDR-Pa and 75 MDR Gram-negative non P. aeruginosa infections). The incidence of MDR-Pa infections was found as 3.1/1,000 admissions. Multivariate analysis showed that multiple invasive procedures (Relative Risk 24.57 (95% Confidence Interval 4.45135.73) p<0.001), burn (RR 13.66 (CI 407-45.80) p<0.001), malignity (RR 12.50 (CI 2.64-59.20) p=0.001), pneumonia (RR 11.91 (CI 2.44-58.16) p=0.002), carbapenem use (RR 4.92 (CI 1.60-15.09) p=0.005) and long hospitalization (> 10 days) (RR 4.68 (CI=2.09-10.49) p<0.001), were found to be risk factors for MDR-Pa. Conclusions: This study revealed that severity of clinical course and carbapenem use are significant risk factors for MDR-Pa infections