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Öğe Andiscriminated aseptic meningitis case between rickettsia and leptospiral meningitis(TIP ARASTIRMALARI DERNEGI, 2008) Özdemir, Davut; Sencan, İrfan; Yıldırım, Mustafa; Güçlü, Ertuğrul; Yavuz, Tevik; Karabay, OğuzRickettsial meningitis and leptospiral meningitis should be included in the differential diagnosis of aseptic meningitis in patients exposed to endemic areas. In this report we describe a case of aseptic meningitis in which neither a rickettsial nor leptospiral etiology could be established.Öğe Brusellozise bağlı subakut tiroidit olgu sunumu ve literatür değerlendirmesi(2007) Küçükbayrak, Abdülkadir; Yildirim, Mustafa; Özdemir, Davut; Gergin, Rezan; Güçlü, ErtuğrulBrusellozis dünyada yaygın olarak görülen zoonotik bir hastalıktır. Hastalık birçok sistemi tutmakla birlikte tiroid bezi tutulumu nadirdir. Tanı; brusellozise ait klinik bulguları olanlar kişilerde standart tüp aglütinasyon testiyle (endemik olmayan yerlerde >1/1160, endemik yerlerde >1/320 veya >l/640) ve/veya kan, diğer doku veya vücut sıvılarından Brucella spp.'nin izole edilmesiyle konulur. Standart tüp aglütinasyon testinin negatif olması durumunda; uygun klinik bulguların varlığında Brusella Ig M antikorlarının pozitif olmasıyla da tanı konulabilir. Bu yazıda, subakut tiroidit tanısıyla takip edilen 19 yaşında bir bayan hasta sunulmuştur. Brusellozise bağlı subakut tiroidit tanısı; klinik bulgular, tiroid fonksiyon testlerinin, tiroglobülin ve tiroglobülin antikorlarının yüksekliği, Brusella Ig M antikorlarının pozitif bulunması ve tiroid sintigrafisi ile konulmuştur.Öğe Comparison of the effect of filgrastim vs. lenograstim started during febrile neutropenia attack in patients with solid tumors(Elsevier Sci Ltd, 2013) Sönmez, Özlem Uysal; Güçlü, Ertuğrul; Türker, İbrahim; Üyetürk, Ümmügül; Bal, ÖznurÖğe Frequency of nasal helicobacter pylori carriage among cooks(Pakistan Medical Assoc, 2013) Karabay, Oğuz; Güçlü, Ertuğrul; Koçoğlu, Esra; Özdemir, Davut; Şencan, İrfanObjective: To investigate the frequency of nasal helicobacter pylori carriage among cooks living in Bolu, Ardahan and Sakarya province of Turkey. Methods: A total of 54 cooks (10 from Bolu, 29 from Ardahan and 15 from Sakarya) were enrolled. Nasal helicobacter was tested using polymerase chain reaction. Results: Helicobacter pylori was detected in only one cook. Conclusion: Nasal Helicobacter pylori colonisation ratio in cooks in Turkey was found to be very low. Presumably hand hygiene compliance lowered the frequency.Öğe Impact of antimicrobial drug restrictions on doctors’ behaviors(2016) Karabay, Oğuz; Hoşoğlu, Salih; Güçlü, Ertuğrul; Akalın, Şerife; Altay, Fatma Aybala; Koçoğlu, Mücahide Esra; Küçükbayrak, AbdulkadirBackground/aim: Broad-spectrum antibiotics have become available for use only with the approval of infectious disease specialists (IDSs) since 2003 in Turkey. This study aimed to analyze the tendencies of doctors who are not disease specialists (non-IDSs) towards the restriction of antibiotics. Materials and methods: A questionnaire form was prepared, which included a total of 22 questions about the impact of antibiotic restriction (AR) policy, the role of IDSs in the restriction, and the perception of this change in antibiotic consumption. The questionnaire was completed by each participating physician. Results: A total of 1906 specialists from 20 cities in Turkey participated in the study. Of those who participated, 1271 (67.5%) had ≤5 years of occupational experience (junior specialists = JSs) and 942 (49.4%) of them were physicians. Specialists having >5 years of occupational experience in their branch expressed that they followed the antibiotic guidelines more strictly than the JSs (P < 0.05) and 755 of physicians (88%) and 720 of surgeons (84.6%) thought that the AR policy was necessary and useful (P < 0.05). Conclusion: This study indicated that the AR policy was supported by most of the specialists. Physicians supported this restriction policy more so than surgeons did.Öğe Serum neopterin concentrations in healthy healthcare workers compared with healthy controls and patients with pulmonary tuberculosis(Int Scientific Information, Inc, 2006) Özdemir, Davut; Cesur, Salih; Annakkaya, Ali Nihat; Tarhan, Gülnür; Güçlü, Ertuğrul; Şencan, İrfan; Balbay, ÖnerBackground: The aim of this study was to compare Serum neopterin levels in patients with active pulmonary tuberculosis, healthy healthcare workers who had close contact with patients, and healthy volunteers. PVII of the healthy volunteers stated that they had not encountered possible risk factors for exposure to Mycobacterium tuberculosis infection. 0 Material/Methods: Thirty-nine patients, 39 healthy healthcare workers, and a control group of 39 healthy volunteers who had no infection or other diseases were included in this study Neopterin assay was performed in accordance with the manufacturer's instructions. Results: Serum neopterin levels were 18.6 +/- 14.2 nmol/l in patients, 9.8 +/- 2.9 nmol/l in healthy healthcare workers, and 3.4 +/- 5.2 nmol/l in healthy volunteers. Serum neopterin levels in each group were significantly different from each other (p<0.01). Conclusions: Levels of neopterin in patients and healthy healthcare workers significantly differ from the levels in healthy controls. The higher serum neopterin levels in healthy healthcare workers may be attributed to latent Mycobacterium. tuberculosis infection, but it does not seem to be Used in the diagnosis of latent mycobacterium tuberculosis infection alone. However, more experiences are needed.Öğe Which one is more effective, filgrastim or lenograstim, during febrile neutropenia attack in hospitalized patients with solid tumors?(Asian Pacific Organization for Cancer Prevention, 2015) Sönmez, Özlem Uysal; Güçlü, Ertuğrul; Üyetürk, Ümmügül; Esbah, Oruç; Türker, İbrahimBackground: Chemotherapy-induced febrile neutropenia (FN) with solid tumors causes mortality and morbidity at a significant rate. The purpose of this study was to compare the effects of filgastrim and lenograstim started with the first dose of antibiotics in hospitalized patients diagnosed with FN. Materials and Methods: Between February 2009 and May 2012, 151 patients diagnosed with FN were evaluated, retrospectively. In those considered appropriate for hospitalization, convenient antibiotic therapy with granulocyte colony stimulating factors was started within first 30 minutes by completing necessary examinations in accordance with FEN guide recommendations. Results: In this study, 175 febrile neutropenia attacks in 151 patients were examined. Seventy three of the patients were male and 78 were female. The average age was 53.6 and 53.6, respectively. The most common solid tumor was breast carcinoma in 38 (25%) . One hundred and five FN patients (58%) were those who received granulocyte colony stimulating factors as primary prophylaxis. Conclusions: While studies comparing both drugs generally involve treatments started for prophylaxis, this study compared the treatment given during the febrile neutropenia attack. Compared to lenograstim, filgastrim shortens the duration of hospitalization during febrile neutropenia attack by facilitating faster recovery with solid tumors.
