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Öğe A case of melanonychia due to Candida albicans(Blackwell Publishing, 2006) Parlak, Ali Haydar; Göksüğür, Nadir; Karabay, OğuzCandida species rarely cause black pigmentation of infected nails and only a few cases have been reported in the literature. We describe a 53-year-old white man who had diffuse melanonychia of the fourth right fingernail due to C. albicans. A progressive dark pigmentation of his nail appeared over 6 months, following paronychial inflammation. The melanonychia was associated with brittleness. There was no onycholysis or hyperkeratosis. Direct examination with potassium hydroxide demonstrated round yeast cells in the specimen. The samples were cultured on Sabouraud glucose agar containing chloramphenicol at 27 degrees C and showed white growth after a few days. The patient was successfully treated with systemic itraconazole.Öğe The frequency of scarring after genital ulcers in Behcet's syndrome: a prospective study(Blackwell Publishing, 2006) Mat, M. Cem; Göksüğür, Nadir; Engin, Burhan; Yurdakul, Sabahattin; Yazıcı, HasanBackground Although genital ulceration with or without scar formation is an important manifestation of Behcet's syndrome, formal data on the rate of genital scarring are lacking. Objective To study prospectively the frequency of genital scar formation after genital ulcers in patients with Behcet's syndrome. Methods One hundred and two patients (72 males and 30 females) with fresh genital ulcers presenting at a dedicated Behcet's syndrome outpatient clinic were followed for 6 weeks. The ulcer location, size, and frequency of scar formation were noted. All patients were treated with similar topical therapy. Results Two hundred and ten genital ulcers were followed in both sexes. The rate of scar formation was 66.2% (102/154) in male patients and 60.7% (34/56) in female patients. When genital ulcers were stratified as a function of size, large genital ulcers (>= 1 cm in diameter) developed scars more frequently than did smaller ulcers (< 1 cm). The rate of scar formation in male patients with large genital ulcers was 89.4% (59/66) and with small ulcers was 48.9% (43/88) (P < 0.001). In females, all 19 large ulcers healed with scarring, and the same was true for 40.5% (15/37) of the small ulcers (chi(2) = 18.61, P < 0.001). Conclusion About two-thirds of genital ulcers in Behcet's syndrome leave scars. The rate of scar formation depends on the ulcer size.Öğe Itchy and painful ulceration on the penis(Amer Acad Family Physicians, 2006) Göksüğür, Nadir; Parlak, Ali HaydarA 61-year-old man presented with a five-day history of a penile ulceration. It began as an itchy, erythematous lesion and gradually became pigmented, blistered, and ulcerated (see accompanying figure). He had a history of benign prostatic hyperplasia for which he took tamsulosin (Flomax).
