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Öğe The combined S velocity achieved from tricuspid annulus and pulmonary annulus with tissue Doppler imaging could predict the proximal right coronary artery occlusion in patients with inferior myocardial infarction(2022) Acar, Emrah; Ozgul, Neryan; Donmez, Ibrahim; Yalcin, Osman Yasin; Kayabas, Oguz; Alan, Sait; Izgi, Ibrahim AkinAim: To investigate if combined S velocity (CSV) calculated from tricuspid annulus and pulmonary annulus\rwith tissue Doppler imaging in individuals with acute inferior myocardial infarction were linked to proximal\rRCA lesions.\rMethods: The study comprised 48 patient who had been diagnosed with acute inferior myocardial infarction\rand had culprit lesions in the right coronary artery. The RCA occlusion in Group A was proximal to the right\rventricular branch, while the RCA occlusion in Group B was distant to the RV branch. The combined S\rvelocity was tested, as well as other echocardiographic parameters.\rResults: In terms of metrics indicating right ventricular function, there were substantial disparities between\rthe groups. A favorable association was established in the univariate correlation analysis between CSV and\rtissue Doppler imaging derived tricuspid annulus systolic velocity (St), pulmonary annulus motion velocity\revaluated by TDI (PAMVUT), RV tricuspid annular plane systolic excursion (TAPSE), and fractional area\rchange (FAC). CSV was identified as an independent predictor of proximal RCA occlusion in a multivariate\rlogistic regression test. In the ROC analysis, CSV<18.3 cm/s and PAMVUT<8.6 cm/s indicated proximal\rRCA occlusion with 83 percent sensitivity and 71 percent specificity (AUC=0.83, p<0.001), and 85 percent\rsensitivity and 71 percent specificity (AUC=0.81, p<0.001), respectively.\rConclusion: CSV measurements were revealed to be an important predictor of proximal RCA occlusions in\rthis investigation.Öğe The Correlation of C-Reactive Protein/Albumin, Mii-1 and Mii-2 Indexes With Hospitalization and Mortality in Stanford Type A Aortic Dissection(2022) Demirel, Mustafa Enes; Korkmaz, Ufuk Turan Kürşat; Donmez, Ibrahim; Özçelik, Ayşenur; Korkmaz, AbdullahAim: In this study we aimed to investigate the relationship between C-Reactive Protein (CRP)/albumin ratio, MII-1 and MII-2 indexes in hospitalization and mortality due to aortic dissection. Material and Method: Patients who presented to our emergency department with a sudden-onset, sharp and stabbing chest pain and diagnosed with Stanford type A aortic dissection were included in the study. Patients’ demographics such as age and gender, hemogram parameters, ratios, indexes, hospitalization and mortality status were recorded. Demographic features, hemogram parameters, ratios and indexes were compared between the survivor and exitus patients. Results: A total of 71 patients who presented to the emergency department with sudden-onset stabbing chest pain and subsequently diagnosed with aortic dissection were included in this retrospective study. The median age of the patients was negatively correlated with albumin (r=-0.27, p=0.021), hemoglobin (r=-0.28, p=0.019). Hemoglobin values were significantly higher in male than in female patients. The median length of stay in the hospital was found as 10 (7-14) days. In the correlation analysis of the hemogram parameters, indexes and length of stay in the hospital; CRP and CRP/Albumin ratio were significantly correlated with length of stay in the hospital in positive direction. Conclusion: The results of this study point out a significant correlation between CRP, CRP/albumin ratio and length of stay in hospital. This information might be helpful in rapid decision making process for early diagnosis and treatment of the disease.Öğe The right ventricle outflow tract systolic function could predict the severity of the cirrhosis(Tubitak Scientific & Technological Research Council Turkey, 2024) Donmez, Ibrahim; Can, Guray; Acar, EmrahBackground/aim: The distinctive liver framework is converted into structurally abnormal nodules as a consequence of tissue fibrosis in cirrhosis. Cardiac dysfunction in cirrhosis was described, and the term cirrhotic cardiomyopathy (CCM) was coined to describe this syndrome. Recent research has shown that the contractile characteristics of the right ventricular outflow tract (RVOT) have a significant impact on right ventricular functions. The right ventricular outflow tract -systolic excursion is an important systolic function marker of RVOT (RVOT-SE). There has yet to be published research on RVOT function in cirrhotic patients. We looked at the relationship between cirrhosis severity and the RVOT-SE. Materials and methods: Sixty-nine consecutive hepatic cirrhotic patients were recruited for the research between June 1, 2018 and January 1, 2022. A medical history, thorough physical examination, laboratory investigations, echocardiographic evaluation, and RVOT-SE were obtained. The patients were separated into two groups: those with compensated cirrhosis (Child -Pugh class 1) and those with decompensated cirrhosis (Child -Pugh class 2 and 3). Results: On the numerous standard echocardiographic parameters that examined the diameter and function of the left ventricle, we observed no significant difference between groups. Nevertheless, a statistically significant difference in Right Ventricle Wall (RVW) (p = 0.014), systolic pulmonary artery pressure (sPAP) (p = 0.034), RVOT-SE (p = 0.003), and Tricuspid Annular Plane Systolic Excursion (TAPSE) (p = 0.042) was detected across cirrhosis groups. The RVOT-SE had a positive correlation with cirrhosis severity (OR: 0.607; 95% CI: 0.425-0.866; p = 0.006), according to multiple logistic regression studies. According to the ROC curve study, RVOT-SE 8.8 cm/s predicted decompensated cirrhosis with 72% sensitivity and 72.7% specificity (AUC = 0.715, p: 0.001). Conclusion: In the current study, we found that RVOT-SE was related to the severity of cirrhosis. Larger patient cohorts and multicenter investigations will provide light on the notion.Öğe Serum uric acid to HDL-cholesterol ratio could be promising predictor of atrioventricular nodal reentrant tachycardia(2023) Donmez, Ibrahim; Cosgun, Mehmet; Bayraktar, Muhammed Fatih; Korkmaz, Ufuk Turan Kursat; Demirel, Mustafa Enes; Acar, Emrah; Gunes, YilmazAim: Paroxysmal supraventricular tachycardia (PSVT), particularly atrioventricular nodal reentrant tachycardia (AVNRT), is a common arrhythmia with no associated structural heart disease. Inflammation has been implicated in the pathogenesis of arrhythmias. Uric acid to high density lipoprotein (HDL)-cholesterol ratio (UHR) is a novel inflammation marker that has been investigated in various conditions. This study aimed to explore the potential association between UHR and AVNRT. Materials and Methods: A total of 136 patients were included in the study, including 86 patients with AVNRT and 50 controls with normal electrophysiological study. All patients’ medical records were reviewed, and data were obtained retrospectively. We recorded baseline features, hematologic and biochemical markers, and determined the UHR value. Results: UHR (p=0.031) and uric acid (p<0.001) levels were significantly higher, while HDL cholesterol (p=0.031) levels were significantly lower in the AVNRT group. Neutrophil leukocyte ratio (NLR) was also higher in the AVNRT group (p=0.034). However, in multivariate analysis, only UHR emerged as an independent predictor for AVNRT (OR: 1.088; 95%CI: 1.022 – 1.159; p=0.008). ROC curve analysis suggested a UHR cut-off > 14.05 for predicting AVNRT with 56% sensitivity and 76% specificity. Conclusion: This study identifies UHR as a promising predictor for AVNRT, shedding light on the potential role of inflammation in the arrhythmia’s development. Utilizing UHR as a readily accessible marker in the evaluation of AVNRT patients may have clinical implications.
