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    Characteristics of Pellet Injuries to the Orbit
    (Karger, 2009) Kukner, A. Sahap; Yilmaz, Turgut; Celebi, Serdal; Karslioglu, Safak; Alagoz, Guersoy; Serin, Didem; Acar, M. Akif
    Purpose: To investigate the features of orbital injuries by pellets fired from the front. Design: Retrospective, 4 cases of pellet injuries. Methods: Five orbits of 4 patients who sustained pellet injuries received from the front were reviewed retrospectively. The course of injury and results were assessed. Radiological examinations were reviewed. The patients were evaluated between December 1996 and June 2004. Results: Five orbits of 4 patients sustained injuries caused by pellets fired from an anterior direction. The globe in the injured orbit was intact in 2 cases. Severe loss of vision was also present in these 2 globes due to optic nerve involvement. Final visual acuity was down to no light perception in 4 eyes and limited to light perception in 1 eye. Conclusions: The prognosis of orbital pellet injuries is, unfortunately, poor. A pellet passing through the floor of the orbit often causes double perforation of the globe and, once in the orbital aperture, it travels towards the apex as a result of the conical shape of the orbit and lodges in the optic canal or its entrance, severely damaging the optic nerve. Surgery or other treatments are usually unsuccessful. Even if the globe is intact, vision is usually severely impaired. Copyright (c) 2009 S. Karger AG, Basel
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    Comparison of the Effect of Different Treatment Doses of Intrastromal Vancomycin in a Rabbit Model of Methicillin-Resistant Staphylococcus Aureus (MRSA) Keratitis
    (Taylor & Francis Inc, 2024) Bayrak, Abdullah; Celebi, Serdal; Avcioglu, Fatma; Alkan, Yunus
    PurposeTo compare the effect of different doses of vancomycin on a rabbit model of MRSA keratitis.MethodsTwenty-four eyes of 24 New-Zealand White rabbits were included in the study. MRSA keratitis was applied to 24 left eyes of 24 New Zealand rabbits. Twenty-four hours after MRSA inoculation; 0.5 mg/0.1 mL, 1 mg/0.1 mL, and 2 mg/0.1 mL and balanced salt solution were administered to 6 rabbits in 4 groups, respectively.ResultsThe effect of different doses of vancomycin on reducing bacterial load was found to be statistically significant when each was compared to the control group (p = 0.006). When comparing the dosages with each other, no superiority was shown (p = 0.297, p = 0.749, p = 0.262 respectively). There was a significant increase in the posttreatment total clinical score in the control and 2 mg/0.1 mL groups compared to the pretreatment score (p = 0.001, p = 0.001 respectively).ConclusionIt is emphasized that necessary treatment can be achieved by administering less antibiotic (0.5 mg/0.1 mL) to the corneal intrastromal area.