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    The Association of Binge Eating Disorder with Glycemic Control in Patients with Type 2 Diabetes
    (Galenos Yayincilik, 2011) Canan, Fatih; Gungor, Adem; Onder, Elif; Celbek, Gokhan; Aydin, Yusuf; Alcelik, Aytekin
    Objective: Our aim was to assess the prevalence of binge eating disorder (BED) in individuals with type 2 diabetes and to investigate whether a comorbidity with BED would affect glycemic control in these patients. Materials and Methods: Eighty-two type 2 diabetic patients were enrolled. The participants were assessed for eating disorders by a psychiatrist. Blood samples were drawn and HbA1c and other biochemical parameters were measured. Results: Of the 82 subjects, 27 (34.1%) met the criteria for BED. No other types of eating disorders were detected. HbA1c was significantly higher in individuals with BED (p< 0.05). Conclusion: Our findings reveal that BED is highly prevalent among type 2 diabetic patients and it impairs glycemic control. Thus, patients with type 2 diabetes should be assessed carefully for eating disorders.
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    Carotis lntima Media Thickness in Female Patiens with Subclinical Hypothyroidism
    (Galenos Yayincilik, 2010) Onder, Elif; Aydin, Yusuf; Gungor, Adem; Celbek, Gokhan; Kir, Seher; Yildinm, Hayriye Ak; Demirin, Hilmi
    Objective: Recent studies have shown that subclinical hypothyroidism (SCH) has similar cardiovascular risks with clinical hypothyroidism (CH). We evaluated carotis intima media thickness (CIMTI-indicator of early changes in atherosclerotic process-in female patients, who have either CH or SCH, with similar age and demographic features. Materials and Methods: In this study, we included 81 female patients admitted to internal medicine and endocrinology outpatient clinic, diagnosed with CH (30) or SCH (51) according to their laboratory findings and who hove not previously received treatment and 38 healthy women. BMI (body moss index), sistolic and diastolic blood pressure, triglycerides (TG), total cholesterol (TC), LDL cholesterol (LDL-C), HDL cholesterol (HDL-C), vitamin B-12, folate, homocysteine, high-sensitive C-reactive protein (Hs CRP), and CIMT were measured in all participants Results: There was not a statistical difference between the groups in TG, TC, HDL-C, LDL-C, vitamin B-12, and folate levels (p>0.05). On the other hand, SCH and CH groups differed statistically significantly from the control group for Hs CRP (p=0.011), homocysteine (p<0.001), and CIMT values. Additionally, age was found to be the most important factor for increase in CIMT when multiple linear regression analysis was performed. Conclusions: Lack of difference between CH patients and SCH patients in respect to Hs CRP, homocystein, and CIMT shows that inflammation and increase in CIMT starts during SCH period. Hence, we think that the increase in CIMT in SCH patients when TSH levels are higher than the normal range is a clinically important sign of early cardiovascular diseases.