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Öğe Akciğer kitlelerinde biyopsi yapılacak kesimin belirlenmesinde difüzyon ağırlıklı görüntüleme ve görünür difüzyon katsayısı değerlerinin rolü(Bolu Abant İzzet Baysal Üniversitesi, 2014) Canan, Arzu; Gürel, KamilAmaç: Bilgisayarlı tomografi (BT) eşliğinde transtorasik biyopsi yapılacak akciğer nodül ve kitlelerinde manyetik rezonans görüntüleme (MRG) ve difüzyon ağırlıklı görüntüleme (DAG) tetkiklerini kullanarak tek lezyon varlığında lezyonun tümöral hücre yoğunluğu fazla olan yerini, birden fazla lezyon varlığında ise malignite olasılığı daha yüksek olan lezyonu tespit etmek. Böylelikle BT eşliğinde biyopsi işlemine kılavuz yöntem olarak DAG ve görünür difüzyon katsayısı (ADC) haritasının kullanıp kullanılamayacağını araştırmak. Gereç ve Yöntemler: Mart 2013- Ekim 2014 tarihleri arasında Abant İzzet Baysal Üniversitesi Girişimsel Radyoloji Bilim Dalı'na akciğer malignitesi şüphesi ile transtorasik akciğer biyopsisi için başvuran 116 hastadan 100'ünde lezyona yönelik MRG (T1A,T2A,STIR) ve DAG (b=50, b=400, b=800) tetkikleri yapıldı. Her hastada b=800 görüntüleri kullanılarak ADC haritası oluşturuldu. Biyopsi işlemi öncesinde lezyonun MRG ve DAG özellikleri değerlendirilerek, ADC haritasında görsel olarak lezyonun en hipointens olan kesiminden ya da en hipointens olan lezyondan biyopsi yapıldı. Biyopsi işlemi öncesi pratik olmadığı için lezyon DAG/ADC sinyal özelliklerinin değerlendirilmesi ve ADC ölçümleri retrospektif olarak yapıldı. Bulgular: MRG ve DAG/ADC tetkikleri yapılan 100 hastadan 72'si çalışmaya dahil olabildi. Yetmiş iki hastadaki 74 lezyonun tamamında histopatolojik olarak tanı konmuş olup tanısallık %100'dür. Çalışmada benign lezyonların MRG ve ADC görüntülerinde daha homojen, malign lezyonların ise daha heterojen olduğu saptandı (p=0.011). ADC haritasında malign lezyonların benign olanlara kıyasla daha hipointens olduğu (p=0.001) ve difüzyon kısıtlılığı (p=0.002) gösterdiği bulundu. Ancak malign ve benign gruplar arasında ADC değerleri açısından istatistiksel olarak anlamlı fark saptanmadı (p=0.147). Sonuç: Seçilmiş hastalarda BT eşliğinde transtorasik biyopsi öncesi alınacak ADC haritası görüntüleri yeni bir kılavuz yöntem olarak kullanılabilir. ADC haritasında hipointens alanların biyopsiye hedef olarak alınması, zaman alan ve şüpheli ADC ölçümleri yapılmasına gerek bırakmamaktadır. Anahtar sözcükler: Akciğer kanseri, difüzyon ağırlıklı görüntüleme, görüntüleme eşliğinde biyopsi.Öğe Artificial neural network-based classification system for lung nodules on computed tomography scans(Ieee, 2014) Dandil, Emre; Çakıroğlu, Murat; Eksi, Ziya; Özkan, Murat; Kurt, Özlem Kar; Canan, ArzuLung cancer is the most common type of cancer among various cancers with the highest mortality rate. The fact that nodules that form on the lungs are in different shapes such as round or spiral in some cases makes their detection difficult. Early diagnosis facilitates identification of treatment phases and increases success rates in treatment. In this study, a holistic Computer Aided Diagnosis (CAD) system has been developed by using Computed-Tomography (CT) images to ensure early diagnosis of lung cancer and differentiation between benign and malignant tumors. The designed CAD system provides segmentation of nodules on the lobes with neural networks model of Self-Organizing Maps (SOM) and ensures classification between benign and malignant nodules with the help of ANN (Artificial Neural Network). Performance values of 90.63% accuracy, 92.30% sensitivity and 89.47% specificity were acquired in the CAD system which utilized a total of 128 CT images obtained from 47 patients.Öğe Bilateral Thalamic Infarct: Occlusion of the Percheron Artery(Aves, 2013) Altunrende, S. Sevil; Canan, Arzu; Yildiz, Serpil; Yildiz, NebilÖğe Bilateral thalamic infarct: Occlusion of the percheron artery(2013) Altunrende, Ş. Sevil; Canan, Arzu; Yıldız, Serpil; Yıldız, NebilThe arterial blood supply of the thalamus and midbrain is provided by perforating arteries which could have several variations. The artery of Percheron is a variant which originates from the P1 segment of the posterior cerebral artery. Its occlusion results in infarction of bilateral paramedian thalami and mesencephalon (1). We would like to draw the reader's attention to a patient with occlusion of the artery of Percheron.Öğe Changes in the size of breast lesions during menstrual cycle observed by ultrasound: An initial study(Scientific Publishers of India, 2017) Dagistan, Emine; Canan, Arzu; Halicioglu, Siddika; Cosgun, Zeliha; Gurel, SafiyePurpose: We aimed to evaluate changes in size of breast lesions during menstrual phases. Material and methods: In this prospective study, 46 women aged 18-35 years old who were referred to our radiology clinic for breast sonography and had cystic or solid breast lesions larger than 5 mm were enrolled to the study. Breast ultrasound (US) was performed at two different times; one within 5 days before and one within 5 days after menstrual bleeding. Anteroposterior and transverse length of the lesions were measured. Results: In total, 145 breast lesions were detected by US. Of these lesions, 6 were visualized in premenstrual phase but were not observed in postmenstrual phase. 6 lesions different were not visualized in premenstrual, but were detected in postmenstrual phase. One hundred and twenty-three lesions were visualized by US both in luteal and follicular phases. Conclusions: Timing of breast US might cause false results and unnecessary further investigations. Therefore, we suggest that breast US in women should be performed in follicular phase of the menstrual cycle. © 2017, Scientific Publishers of India. All Rights Reserved.Öğe Changes in the size of breast lesions during menstrual cycle observed by ultrasound: an initial study.(Allied Acad, 2017) Dağıstan, Emine; Canan, Arzu; Halıcıoğlu, Sıddıka; Coşgun, Zeliha; Gürel, SafiyePurpose: We aimed to evaluate changes in size of breast lesions during menstrual phases. Material and methods: In this prospective study, 46 women aged 18-35 years old who were referred to our radiology clinic for breast sonography and had cystic or solid breast lesions larger than 5 mm were enrolled to the study. Breast ultrasound (US) was performed at two different times; one within 5 days before and one within 5 days after menstrual bleeding. Anteroposterior and transverse length of the lesions were measured. Results: In total, 145 breast lesions were detected by US. Of these lesions, 6 were visualized in premenstrual phase but were not observed in postmenstrual phase. 6 lesions different were not visualized in premenstrual, but were detected in postmenstrual phase. One hundred and twenty-three lesions were visualized by US both in luteal and follicular phases. Conclusions: Timing of breast US might cause false results and unnecessary further investigations. Therefore, we suggest that breast US in women should be performed in follicular phase of the menstrual cycle.Öğe Mean platelet volume and D-dimer in patients with suspected deep venous thrombosis(Springer, 2012) Canan, Arzu; Halıcıoğlu, Sıddıka Sezgin; Gürel, SafiyeThe aim of this retrospective study was to evaluate the diagnostic value of mean platelet volume (MPV) and D-dimer for acute deep venous thromboembolism (DVT). Two hundred and fifty six patients who presented to the emergency or cardiovascular surgery department with suspected lower limb DVT were retrospectively recruited. Plasma levels of MPV, platelet count, and D-dimer were obtained and duplex sonography examination was performed for all patients. Eighty four patients had acute DVT which was diagnosed by duplex ultrasonography. MPV was significantly higher in patients with DVT than in those without DVT (p < 0.01). The mean MPV was 7.97 +/- A 17.8 and 7.58 +/- A 0.87 fL in patients with DVT and without DVT, respectively (p < 0.01). D-dimer was significantly higher in patients with DVT (p < 0.01). For all the patients, a positive MPV when the cut-off value was 7.3 fL, had 69.7 % sensitivity and 43.9 % specificity. D-dimer (with a cut-off value of 0.5 mu g/mL) had 82.9 % sensitivity and 32.7 % specificity. In case of combination of MPV and D-dimer, the specificity exceeded (65.9 %) despite the reduction in sensitivity (59.2 %). Elevated MPV was found to be associated with acute DVT and high levels of MPV might increase the specificity of D-dimer for exclusion of DVT.Öğe Morphometric measurements of the cranium in congenital bilateral blind males and females(Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2013) Kosif, Rengin; Sırmatel, Öcal; Canan, ArzuCranium dimensions differ according to racial, geopraphic, ethnic and nutritional factors. This study will shed light on the question: "Is there a difference in the cranial distances measured between congenital bilateral blind people and healthy individuals?" Nine anthropometric measures were performed on the brain MRI midsagittally obtained from male and female congenital bilateral blinds. The anthropometric measures taken included the glabella-opisthocranion, nasion-dorsum sellae, dorsum sellae- opisthocranion, nasion-basion, nasion-opisthion, basion-opisthion, prosthion-basion, basion-vertex and the clival angle. In addition, the supratentorial and infratentorial areas were calculated. Glabella-opisthocranion, nasion-dorsum sellae, nasion-basion, prosthion-basion and clival angle were found to be smaller in the congenital bilateral blind females compared to the healthy group, but these results were not statistically significant. Whereas, other measures out of the basion-opisthion were found to be smaller in the congenital bilateral blind males than in the healthy subjects. Of these results, the distance between glabella-opisthocranion, nasion-dorsum sellae and nasion-basion was significantly smaller compared to the measurements taken from the healthy male group. The infratentorial area was significantly smaller in congenital blind male subjects and the supratentorial area was significantly larger in congenital blind female subjects. This study has revealed that the cranium dimensions of congenital blind people are to different from normal individuals. The most significant difference was in the distance of the nasion-dorsum sellae. The region anterior to the basion and dorsum sellae was prominently smaller. The infratentorial area was significantly smaller in congenital blind male subjects and the supratentorial area was significantly larger in congenital blind female subjects. (C) 2013 Association of Basic Medical Sciences of FB&H. All rights reservedÖğe Multiple tendon xanthomas in patient with heterozygous familial hypercholesterolaemia: Sonographic and MRI findings(2013) Dağıstan, Emine; Canan, Arzu; Kızıldağ, Betül; Barut, Abdullah YükselTendon xanthomas are a component of familial hypercholesterolaemia, which is a hereditary disease and characterised by elevated low-density lipo protein cholesterol plasma levels and premature coronary artery disease. Tendon xanthomas are diagnostic for heterozygous familial hypercholesterolaemia (HFH) and they mostly occur in Achilles tendon. Sonography and MRI are superior to clinical assessment and are useful in detecting tendon xanthomas. In this report, we present ultrasonographic and MRI findings of multiple tendon xanthomas in a case of HFH. Copyright © 2013 BMJ Publishing Group. All rights reserved.Öğe Ovaryan hiperstimulasyon sendromunun ultrasonografik özellikleri: Olgu sunumu(Duzce Univ, 2014) Canan, Arzu; Altunrende, Şerife SevilOvarian hyperstimulation syndrom is a serious entity that develops during in vitro fertilization (IVF) treatment. It can be varying from mild to severe clinical manifestations. To diagnose and to differentiate from the other ovarian pathologies, radiologic examinations, especially ultrasonography is very sufficient. Therefore, radiologist should be aware of this syndrome because of its increased frequency recently. We aimed to report an OHSS case who admitted to our clinic and discuss its radiological features.Öğe Pulmoner trunkusu basılayan sol pulmoner reses hematomu(2014) Canan, Arzu; Halıcıoğlu, Sıddıka; Altunrende, Şerife Sevil; Gürel, SafiyePerikardiyal kavitenin oluşturduğu reses ve sinüslerdeki sıvı, başta lenf nodları olmak üzere birçok mediastinal patolojiyi taklit edebilmektedir. Bu nedenle reses ve sinüslerin normal anatomisi ve radyolojik özelliklerinin bilinmesi mediastinal lezyonların ayırıcı tanısında önem taşımaktadır. Amacımız bu olguda sol pulmoner reses hematomunu ve ikincil etkisini sunmak ve perikardiyal reseslerin radyolojik özelliklerini gözden geçirmektir.Öğe The radiological appearance of a giant intrathoracic fibrolipoma(Turkish Assoc Tuberculosis & Thorax, 2016) Dağıstan, Emine; Barut, Abdullah Yüksel; Karagöz, Yeşim; Fener, Neslihan; Canan, Arzu; Kızıldağ, BetülFibrolipomas are benign variants of lipomas. Although, lipomas are common benign tumors of soft tissue, intrathoracic lipomas especially fibrolipomas are very rare. They usually presents as a sharply delineated mass with a thin capsule/septation. The patients are commonly asymptomatic. Fibrolipomas are determined on chest radiograph incidentally. A radiography only showed the mass and location. Computed tomography (CT), magnetic resonance imaging (MRI) usually reveal characteristic findings of lipomatous mass, that is helpful for diagnosis (1). We report an asymptomatic patient with a pedunculated huge intrathoracic fibrolipoma and its radiological findings. A 45-year-old woman presented to clinic of Chest Disease with desire of check-up because of her age. The patient had no complaints. Her medical history was unremarkable. She was non-smoker, was not on medication. Physical examination revealed a normal blood pressure and pulse. The expansion of the thorax was symmetric. But, breath sounds were absent on the base of right hemithorax and there was dullness on percussion. The results of routine laboratory tests including arterial blood gas analysis were normal. A chest radiograph revealed opacification of the lower part of the right hemithorax because of a well defined enormous mass (Figure 1). Thorax CT was performed to examine the origin of the mass (Figure 2).Öğe The Role of Ultrasound in the Diagnosis of Hydrometrocolpos due to Vaginal Atresia; Case Report(2015) Altunrende, Şerife Sevil; Canan, Arzu; Öztürk, HülyaGiriş: Neonatal hidrometrokolpos kadın üreme yollarının gelişim defektine bağlı gelişen nadir bir anomalisidir. Yenidoğanda genellikle abdominal kitle, nadiren hidroüreteronefroz ile presente olur. Olgu: Bu yazıda 3 günlük yenidoğanda yüksek va- jinal atreziye bağlı gelişen dev hidrometrokolpos ve eşlik eden bilateral hidroüreteronefrozun sonogra- fik bulgularını sunduk. Sonuç: Ultrason abdominal kitlenin orijini ve komplikasyonlarını ortaya koyabilen önemli bir ta- nısal modalitedir.Öğe Silent ischemic pancreatitis following urosepsis(Ondokuz Mayıs Üniversitesi, 2013) Aktaş, Gülali; Duran, Arif; Alçelik, Aytekin; Karaçay, Sevim; Şavlı, Haluk; Gürel, Safiye; Canan, ArzuPancreatic ischemia is an uncommon cause of acute pancreatitis. Ischemia with resultant pancreatitis has been reported in vasculitis, atheroembolism, intraoperative hypotension, survivors of cardiac arrest and hemorrhagic shock. Ischemic acute pancreatitis is difficult to recognize clinically. In this report we present a 63 year old woman with painless ischemic pancreatitis following urosepsis. We suggest that if a critically ill patient is hypotensive for more than 24-48 hours, amylase levels must be monitored to establish ischemic acute pancreatitis (AP) even if the patient remains asymptomatic. © 2013 OMU.Öğe Suprakondiler proses sendromunda MRG bulguları(2014) Kızıldağ, Betül; Yıldız, Yavuz; Koşar, Şule; Kömürcü, Erkam; Dağıstan, Emine; Canan, ArzuHumerus distal kesiminde anteromediyal yüzeyde gelişen gaga şeklinde kemik çıkıntı ‘suprakondiler spur ya da proçes olarak adlandırılır. Çoğu kez medial epikondile insersiyosu olan Struthers ligamanı ile sonlanmaktadır Humerus distalinde insan türünde yaklaşık %0.1 -2.7 sıklı kla gözlenen bu konjenital anatomik varyasyon diğer n edenlerle çekilen radyogramlarda rastlantısal olarak saptanır. Suprakondiler proses kırılması ya da damar sinir bas ısına yol açması sonucunda nadiren semptomatik hale gelmektedir. Suprakondiler prosesle ilişkili sinir tuzakla nma sendromunun klinik ve elektromyelografi bulguları yanında manyetik rezonans (MR) görünümünün bilinmesi, ayırıcı tanı ve tedaviyi yönlendirme açısından faydalı ol acaktır. Suprakondile r proses sendromlu olguların MR bulguları literatürde az tanımlanmıştır.Bu sunumda 25 yaşında kol ağrısı şikayeti ile ortopedi kliniğine baş vuran ve direkt grafi ve MR bulguları eşliğinde tanısı konan su prakondiler proses sendromlu olgunun klinik ve radyo lojik bulguları, ayırıcı tanıdaki ipuçları, tedavi yaklaşımı literatür eşliğinde tartışılacaktır.Öğe Unilateral absence of sphenoid wing in a Neurofibromatosis type 1 patient: imaging findings(2013) Dağistan, Emine; Canan, Arzu; Barut, Abdullah Yüksel; Karagöz, YeşimNörofibromatozis tip 1 (NF-1) diğer adıyla von Recklinghausen hastalığı nörokutanöz sendromların en sık görülenidir. Pigmente cilt lezyonları ve santral sinir sistemi tümörleri ile karakterizedir. Buna ek olarak tüm sistemleri etkileyebilmektedir. Sfenoid kanat anomalileri nadir görülür ve genellikle NF-1 ile ilişkilidir. Bu nedenle genellikle patognomonik kabul edilir. Bu yazıda sfenoid kanat yokluğuyla karakterize nadir bir NF-1 olgusunu, çok kesitli bilgisayarlı tomografi ve manyetik rezonans görüntüleme bulgularıyla beraber sundukÖğe Unilateral absence of sphenoid wing in a Neurofibromatosis type 1 patient: Imaging findings(2013) Dağıstan, Emine; Canan, Arzu; Barut, Abdullah Yüksel; Karagöz, YeşimNörofibromatozis tip 1 (NF-1) diğer adıyla von Recklinghausen hastalığı nörokutanöz sendromların en sık görülenidir. Pigmente cilt lezyonları ve santral sinir sistemi tümörleri ile karakterizedir. Buna ek olarak tüm sistemleri etkileyebilmektedir. Sfenoid kanat anomalileri nadir görülür ve genellikle NF-1 ile ilişkilidir. Bu nedenle genellikle patognomonik kabul edilir. Bu yazıda sfenoid kanat yokluğuyla karakterize nadir bir NF-1 olgusunu, çok kesitli bilgisayarlı tomografi ve manyetik rezonans görüntüleme bulgularıyla beraber sundukÖğe Wernicke’s encephalopathy following gastrointestinal surgery MRI and DWI findings(Turkish Neurological Society, 2014) Kızıldağ, Betül; Canan, Arzu; Şen, Halil Murat; Taş, Şükrü; Çıkman, Öztekin; Dağıstan, EmineWernicke’s encephalopathy (WE) is a neurologic disorder resulting from thiamine (vitamin B1) deficiency characterised by the ocular signs, altered consciousness and ataxia. It is usually associated with chronic alcohol abuse. Recently, it emerged as a complication following bariatric surgery. The classical clinical triad occurs in a small group of patients, and early replacement of thiamine is an important prognostic factor. Hence, magnetic resonance imaging (MRI) is useful to support the diagnosis. In this case, we report MRI and diffusion weighted imaging findings of WE in a patient without history of alcoholism after gastrointestinal surgery.Öğe ZKTB The Role of Ultrasound in the Diagnosis of Hydrometrocolpos due to Vaginal Atresia; Case Report(2015) Altunrende, Şerife Sevil; Canan, Arzu; Öztürk, HülyaGiriş: Neonatal hidrometrokolpos kadın üreme yollarının gelişim defektine bağlı gelişen nadir bir anomalisidir. Yenidoğanda genellikle abdominal kitle, nadiren hidroüreteronefroz ile presente olur. Olgu: Bu yazıda 3 günlük yenidoğanda yüksek va- jinal atreziye bağlı gelişen dev hidrometrokolpos ve eşlik eden bilateral hidroüreteronefrozun sonogra- fik bulgularını sunduk. Sonuç: Ultrason abdominal kitlenin orijini ve komplikasyonlarını ortaya koyabilen önemli bir ta- nısal modalitedir.
