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Öğe Does melatonin have any effect on liver preservation in ringer lactate and University of Wisconsin solutions?(Blackwell Publishing, 2006) Coşkun, Abdurrahman; Çelik, Ecem; Günal, Ömer; Yavuz, Özlem; Aslaner, Arif; Belenli, Olcay; Memişoğulları, RamazanMelatonin has antioxidant activity and reacts with singlet oxygen, hydroxyl radical, peroxynitrite and nitric oxide. Ischemia and reperfusion is a major problem in organ preservation before transplantation and cause graft failure.Öğe Large pedinculated antral hyperplastic gastric polyp traversed the bulbus causing outlet obstruction and iron deficiency anemia: endoscopic removal(W J G Press, 2003) Alper, Murat; Akcan, Yusuf; Belenli, OlcayWe present here a large (3 cm) hyperplastic gastric polyp prolapsed into duodenum and caused outlet obstruction and iron deficiency anemia in 60 years old male patient. Endoscopic removal was performed successfully.Öğe Papillary carcinoma of the thyroglossal duct cyst in childhood(Springer-Verlag, 2003) Öztürk, Özcan; Demirci, Levent; Egeli, Erol; Çukur, Selma; Belenli, OlcayThyroglossal duct carcinoma is a rare malignancy that is usually diagnosed postoperatively. Approximately 150 cases have been reported in the literature. Eighty-five percent of these were papillary carcinomas. Controversies exist concerning its nature and treatment. In this report, we present an 11-year-old boy with an anterior cervical cystic mass originating in the thyroglossal duct. After a primary Sistrunk procedure, the cyst and tract extending to the foramen caecum at the base of the tongue in continuity with the midportion of the hyoid bone were resected. Histopathologic study demonstrated a papillary carcinoma. After 4 months of follow-up, the patient is asymptomatic without any evidence of recurrence. The clinical and histopathological features and therapeutic options are discussed.Öğe Two successive pregnancies after ursodeoxycholic acid therapy in a previously infertile woman with antimitochondrial antibody-negative primary biliary cirrhosis(Elsevier Inc., 2005) Korkut, Esin; Kısacık, Bünyamin; Akcan, Yusuf; Belenli, Olcay; Bicik, Zerrin; Yücel, OǧuzObjective: To describe the benefit of ursodeoxycholic acid (UDCA) for the initiation and completion of a successful pregnancy in a previously infertile woman with primary biliary cirrhosis. Design: Case report. Setting: A university hospital with relevant departments. Patient(s): A 29-year-old woman with primary biliary cirrhosis and failure to conceive for 6 years. Intervention(s): Establishment of diagnosis with a liver biopsy, pretreatment of patient with UDCA before conception, and continuation of UDCA after first trimester until term. UDCA was used in the second pregnancy again after the first trimester. Main Outcome Measure(s): Achievement of a safe conception and full-term pregnancy. Result(s): Two consecutive successful pregnancies, a healthy 3,250-g male infant and a healthy 3,000-g female infant. The second conception occurred in a period without the use of UDCA, implicating a latent beneficial effect of either UDCA orthe previous pregnancy via some possible immune mechanism. Conclusion(s): Ursodeoxycholic acid could help achieve conception in infertile women with primary biliary cirrhosis. The use of UDCA after the first trimester is shown to be safe in two consecutive pregnancies. Although it cannot be conclusive, the unintentional use of UDCA in the first 20 days after conception did not result in any teratogenicity in the first child. © 2005 by American Society for Reproductive Medicine.