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  • Küçük Resim
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    Electrodermal activities and autonomic nervous system in behcet's patients
    (Springer-Verlag, 2002) Akyol, Melih; Turaçlar, Uğur; Keçeci, Hulusi; Özçelik, Sedat; Marufihah, Mehmet; Erdal, S.; Polat, Murat
    Behcet's disease is often a progressive disorder. In some cases, there is a possibility of subclinical involvement without neurologic signs and symptoms. The autonomic nervous system is affected in Behcet's disease. The aim of the present study was to investigate autonomic nervous system functions in Behcet's patients by analyzing electrodermal activities. A total of 16 patients and 16 healthy volunteers were accepted for the study. Skin potential recordings were taken at room temperature in a quiet place within a Faraday's cage. The mean values of basal skin potentials and skin potential responses in the patients' group were reduced when compared with those of the control group (p=0.0001). There was no difference between the groups regarding the mean values of latencies (p=0.09). The findings suggest that electrodermal activities may reflect autonomic nervous system dysfunction in Behcet's patients, and the measurement of electrodermal activities may be useful for the assessment of autonomic nervous system involvement in Behcet's disease.
  • Küçük Resim
    Öğe
    Habituation of auditory event-related potentials in patients with Behcet's disease
    (2004) Keçeci, Hulusi; Kavak, Ayşe; Akyol, Melih; Değirmenci, Yıldız; Anul, Hüseyin
    Behcet's disease is a progressive and/or relapsing-remitting multisystem inflammatory disorder. Involvement of the central nervous system occurs in 10%-29% of cases with Behcet's disease. The aim of the present study was to assess the effect of repetitive auditory stimulations on event-related potentials (ERP) in patients with Behcet's without neurologic manifestations. The study was performed in 14 patients with Behcet's disease and 14 healthy volunteers. ERPs were recorded from Fz, Cz and Pz. The auditory ERPs test was continued until 20 artefact-free rare tones were averaged, which was accepted as one trial block. After six blocks were obtained in a sequential manner, the test was completed. According to the results of the present study, P300 latency changed in different manners over trial blocks in the two groups. P300 latency values showed a progressive increase in the controls; however this was not determined in the Behcet's group. Thus, habituation was not observed in the patient group. Because of the lack of habituation related to P300 latency, it may be thought that there is an insidious pathologic process in Behcet's disease without neurologic manifestation. © Springer-Verlag Italia 2004.