Yazar "Akman, R. Yavuz" seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Comparison of the effects of various anticancer agents on intestinal anastomosis after intraperitoneal administration(Springer Verlag, 1999) Arıkan, A. Yüksel; Şenel, Ferda M.; Akman, R. Yavuz; Can, CevatIn this study, the effects of intraperitoneal 5-fluorouracil (5-FU), cisplatinum (Cis), adriamycin (Adr), and methotrexate (MTX) administration on rat intestinal anastomosis were compared. Cis and MTX led to significant weight loss in the first 5 days compared with the control group. Within 14 days all rats except the MTX group nearly reached their preoperative weight. No remarkable weight loss or systemic toxicity was observed among the 5-FU and Adr groups. The anastomosis bursting pressure (ABP) at 1 week was significantly lower than that of the control group (P < 0.01 and P < 0.005, respectively). On day 14 the anastomosis bursting pressure in the Cis group was similar to that of the control group but was significantly lower in the MTX group (P < 0.002). Histopathologically, MTX avoided the development of a mucosal layer at the anastomosis site and led to ulcer formation in some of the rats, The ABPs at 7 and 14 days were similar to those in the control group. Neither of the agents had any significant mechanical or histopathologic adverse effects on anastomosis, According to the results of our study, MTX impaired the healing of the anastomosis, and we thus conclude that the intraperitoneal administration of this agent is not safe. On the other hand, Cis showed a detrimental effect on the anastomosis, particularly in the early phase, but this effect disappeared in the late phase. Cis thus should not be administered in the early postoperative phase. As a result, 5-FU and Adr were found to be the safest agents as they did not delay wound healing and did not reduce the anastomotic strength.Öğe Düzce ilinde ilköğretim çağındaki erkek çocuklarda dış genital organ anomali oranları(2005) Kayıkçı, M. Ali; Çam, Kamil; Akman, R. Yavuz; Erol, AliBu çalışmada Düzce ilinde ilköğretim çağındaki erkek çocuklarda dış genital organ anomali oranlarım belirlenmesi hedeflendi. İl merkezindeki 25 adet ilköğretim okulunda öğrenim görmekte olan ve rastgele örnekleme yöntemi ile 7-15 yaş arasındaki toplam 13420 erkek öğrenciden, 1534 erkek öğrenci çalışmaya dahil edildi. Tüm öğrenciler aynı hekim tarafından okullarında muayene edildi ve tespit edilen dış genital organ anomalileri kaydedildi. Yapılan incelemede 1534 erkek öğrencinin 104'ünde (%7,2) 110 patoloji saptandı. En sık rastlanan patolojiler sırasıyla varikosel, fımosiz ve inmemiş testis idi. Bu çalışmada bir çoğu ilköğretim çağından önce tespit ve tedavi edilmesi gereken dış genital organ anomalileri yüksek oranda bulundu. Dolayısıyla bu sonuç, gerek neonatal dönemde gerekse de sonraki izlemde çocukların genital sistem açısından yeterli kontrollerinin yapılmadığını ve ailelerin bu patolojiler hakkında bilgi sahibi olmadığını göstermektedir.Öğe THE RATIO OF EXTERNAL GENITAL ANOMALIES IN MALE CHILDREN ATTENDING PRIMARY SCHOOL IN DUZCE(Aves, 2005) Kayikci, M. Ali; Cam, Kamil; Akman, R. Yavuz; Erol, AliIntroduction: The aim of the study was to identify the rates of external genital anomalies in male children who are attending primary school in Duzce. Materials and Methods: A total of 1534 children out of 13420 male students attending to 25 primary schools in Duzce were included into the study. The age range was between 7 and 16. The same physician examined all students, and external genital anomalies were identified and noted. Results: In this study, a total of 110 (7.2%) anomalies were identified in 104 students. The most common anomalies were varicocele (3.22%), phimosis (1.49%) and undescended testis (1.10%). Conclusion: The rate of external genital anomalies was found to be remarkably high. Actually, almost all of these anomalies had had to be diagnosed and managed before the school ages. Consequently, the results of the current study suggest that there is an insufficient examination and follow up during the neonatal period extending up to school ages. In addition to this, parents do not have any information about these pathologies. Such undiagnosed pathologies will cause significant psychological and urological problems in these children. They may also progress to tumor or infertility. Therefore, this observation should be regarded as an important public health issue.Öğe The ratio of external genital anomalies in male children attending primary school in Düzce(2005) Kayikçi, M. Ali; Çam, Kamil; Akman, R. Yavuz; Erol, AliIntroduction: The aim of the study was to identify the rates of external genital anomalies in male children who are attending primary school in Düzce. Materials and methods: A total of 1534 children out of 13420 male students attending to 25 primary schools in Düzce were included into the study. The age range was between 7 and 16. The same physician examined all students, and external genital anomalies were identified and noted. Results: In this study, a total of 110 (7.2%) anomalies were identified in 104 students. The most common anomalies were varicocele (3.22%), phimosis (1.49%) and undescended testis (1.10%). Conclusion: The rate of external genital anomalies was found to be remarkably high. Actually, almost all of these anomalies had had to be diagnosed and managed before the school ages. Consequently, the results of the current study suggest that there is an insufficient examination and follow up during the neonatal period extending up to school ages. In addition to this, parents do not have any information about these pathologies. Such undiagnosed pathologies will cause significant psychological and urological problems in these children. They may also progress to tumor or infertility. Therefore, this observation should be regarded as an important public health issue.
