Yazar "Akay, Aynur Pekcanlar" seçeneğine göre listele
Listeleniyor 1 - 10 / 10
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Association of theory of mind and empathy abilities in adolescents with social anxiety disorder(Springer, 2020) Öztürk, Yusuf; Özyurt, Gonca; Turan, Serkan; Mutlu, Caner; Tufan, Ali Evren; Akay, Aynur PekcanlarStudies have shown that elevated empathic abilities and impaired theory of mind (ToM) tasks may be associated with social anxiety disorder (SAD). Adolescence is a critical period for the onset of SAD which may cause impairment in various domains of functioning. We aimed to investigate the association of ToM and empathy characteristics in adolescents diagnosed as having SAD. Forty-one drug-naive adolescents (between 12 and 18 years), who were diagnosed as having SAD without comorbidities were enrolled in the patient group. Forty adolescents in the same age range without any psychiatric disorders were matched as the healthy control group. The sample was evaluated via the Kiddie and Young Adult Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version. The severity of the SAD symptoms was evaluated using the Social Anxiety Scale for Adolescents. ToM was evaluated with the Reading the Mind in the Eyes Test and emotion recognition was assessed by Faces Test. The KA-SI Empathic Tendency Scale was used to assess empathic abilities. The average age was 14.36 +/- 1.41 years in the SAD group and 14.30 +/- 1.04 years in the control group. Twenty-eight adolescents were female in the SAD and control groups. SAD and healthy controls did not differ in terms of sociodemographic data. There were higher scores in the KA-SI cognitive and affective empathic subscales (p < .001 in all scales) in the SAD group compared with the healthy controls. Adolescents with SAD have more difficulties both in Reading the Mind in the Eyes Test and Faces Test. The results of this study may indicate that although adolescents with SAD may be impaired in decoding aspects of ToM they may evaluate themselves as more empathic in self-report tests. The discrepancy between objective tests of ToM decoding and subjective reports of empathy may play an important role in the etiology and treatment of SAD in adolescents.Öğe Atomoxetine treatment may decrease striatal dopaminergic transporter availability after 8 weeks: pilot SPECT report of three cases(Dove Medical Press Ltd, 2015) Akay, Aynur Pekcanlar; Kaya, Gamze Çapa; Baykara, Burak; Demir, Yusuf; Özek, Handan; Öztürk, Yeşim; Tufan, EvrenAttention deficit/hyperactivity disorder is one of the most common neurodevelopmental disorders. The pathophysiology is thought to involve noradrenaline and dopamine. The role of dopamine transporter (DAT) was evaluated in imaging studies using mostly dopamine reuptake inhibitors. Atomoxetine is a selective noradrenaline reuptake inhibitor. Here we report the results of a pilot study conducted to evaluate changes in striatal DAT after 8 weeks of atomoxetine treatment. Our results suggest that 8 weeks of atomoxetine treatment may change striatal DAT bioavailability as measured via SPECT but that change was not correlated with genotype or clinical improvement.Öğe The detect consensus report on Attention Deficit/Hyperactivity Disorder and its management among Turkish children and adolescents (Detect: consensus report on ADHD among Turkish youth)(Frontiers Media Sa, 2024) Ogutlu, Hakan; Kutuk, Ozlem Meryem; Tufan, Ali Evren; Akay, Aynur Pekcanlar; Gundogdu, Ozlem Yildiz; Ercan, Eyup SabriAttention Deficit/Hyperactivity Disorder (ADHD) is one of the most common and heritable neurodevelopmental disorders which may last through the life-span. A consensus report on diagnosis and management of ADHD among Turkish youth was prepared previously. However, the participants as well as the management options were rather limited and developments in the past decade necessitated a revision and update of the consensus. Therefore, this review aims to summarize the consensus among Child and Adolescent Psychiatrists from Turkiye on the nature and management of pediatric ADHD. For those aims, the etiology of ADHD, diagnostic and evaluation process, epidemiology, developmental presentations, differential diagnoses and comorbidities, course/outcome and pharmacological as well as non-pharmacological management options were reviewed and suggestions for clinical practice are presented. Since ADHD is a chronic disorder with wide-ranging effects on functionality that is frequently accompanied by other mental disorders, a multidimensional therapeutic approach is recommended. However, since the disorder has neurobiological basis, pharmacotherapy represents the mainstay of treatment. Additional therapies may include psychosocial therapy, behavioral therapy, school-based therapeutic approaches, and family education. This review provides recommendations for ADHD at the national and global levels. It contains information about ADHD that will contribute to and facilitate clinicians' decision-making processes. It is advisable to consider this guideline in clinical practice.Öğe Dikkat Eksikliği Hiperaktivite Bozukluğu Tanısı Olan Çocukların Ailelerinin Bildirdiği Uyku Alışkanlıklarının ve Uyku Sorunlarının Sağlıklı Kontrollerle Karşılaştırılması(2017) Öztürk, Yusuf; Özyurt, Gonca; Akay, Aynur PekcanlarDikkat Eksikliği ve Hiperaktivite Bozukluğu (DEHB)) tanılı çocukların uyku kalitelerinin etkilendiği gösterilmiştir. Çalışmada DEHB tanısı olan çocukların uyku sorunları ve alışkanlıkları açısından kendi içinde ve sağlıklı kontrollerle karşılaştırılması amaçlanmıştır. Çalışmaya 8-12 yaşları arasında 61 DEHB tanılı olgu ve hastanelerin diğer kliniklerine başvuran yaş ve cinsiyet olarak benzer 87 çocuk katılmıştır. Çalışmada Okul Çağı Çocukları için Duygulanım Bozuklukları ve Şizofreni Görüşme Çizelgesi-Şimdi ve Yaşam Boyu sürümü (ÇDGŞG-ŞY) Du Paul DEHB Değerlendirme Ölçeği uygulanmıştır. Çocuklarda uyku, Çocuklar İçin Uyku Alışkanlıkları Anketi ile değerlendirilmiştir. DEHB grubu sağlıklı kontrollerle karşılaştırıldığında; yatma zamanı direnci, uykuya dalmanın gecikmesi, uyku süresi, uyku kaygısı, gece uyanmaları, parasomnialar, gün içinde uykululuk ve uyku sorunları açısından iki grup arasında istatistiksel anlamlılık bulunurken, uykuda solunum bozulması arasında anlamlı bir farklılık saptanmamıştır. Çalışmamızda, literatüre benzer şekilde, DEHB grubundaki çocukların ebeveynleri tarafından değerlendirilen uyku alışkanlıklarındaki sorunlar sağlıklı kontrollere göre fazla bulunmuştur. Ancak, daha geniş örneklemli ve aktigrafi ve polisonografi gibi daha objektif ölçümlerle yapılan çalışmalar, bu konuda daha fazla bilgi sahibi olmamıza olanak sağlayabilir.Öğe Drug holidays may not affect processing speed while they may reduce beneficial effects on resistance to interference among children with treated with methylphenidate: a single-center, prospective study(Taylor & Francis Ltd, 2020) Göl Özcan, Güler; Öztürk, Yusuf; Sarı, Mesut; İmrek, Yasemin; Özyurt, Gonca; Tufan, Ali Evren; Akay, Aynur PekcanlarObjective This study aimed to investigate the effects of drug holidays during summer vacations among children with attention deficit/hyperactivity disorder (ADHD) who were treated with methylphenidate in terms of ADHD symptoms and executive functions. Methods The study was a prospective cohort study that includes pre-treatment, post-treatment and post-drug holiday evaluations. ADHD symptom severity was evaluated with the Clinical Global Impression Scale (CGI), the Conners' Parental Rating Scale-Short Form (CPRS) and the Conners' Teacher Rating Scale- Short Form (CTRS). The Stroop Color Word Test- TBAG Form (SCWT) was used to evaluate executive functions. Fifty-one patients participated in the study according to the inclusion and exclusion criteria. Methylphenidate (MPH) was started at 0.5 mg/kg/day and titrated weekly to a maximum of 1.2 mg/kg/day. During the follow-up period, 22 (43.0%) of the patients stopped treatment. Results Completion times for all SCWT subtests were significantly reduced after treatment (p < 0.001, p = 0.002, p < 0.001, p = 0.002, p < 0.001; respectively). Mean number of corrections in SCWT-3 and mean number of errors as well as corrections in SCWT-5 significantly reduced after treatment (p = 0.047, p = 0.005, p = 0.007; respectively). Mean number of corrections in SCWT-3 and mean number of errors in SCWT-5 increased significantly after drug holiday compared to post-treatment (p = 0.032 and p = 0.037; respectively). Conclusion Our results suggest that psychomotor speed and resistance to interference improved in children with ADHD receiving methylphenidate treatment. Drug holidays did not affect psychomotor speed while beneficial effects on resistance to interference were reduced with drug holidays.Öğe Emotion dysregulation and social communication problems but not ToM properties may predict obsessive-compulsive disorder symptom severity(Taylor & Francis Ltd, 2023) Öztürk, Yusuf; Özyurt, Gonca; Turan, Serkan; Tufan, Ali Evren; Akay, Aynur PekcanlarObjective: Studies have shown that theory of mind, emotion regulation and pragmatic abilities are negatively affected in people with obsessive-compulsive disorder (OCD). We aimed to investigate theory of mind (ToM) abilities, social responsiveness, pragmatic language, and emotion regulation skills in children with OCD and to compare them to healthy controls. Methods: This study was designed as a single-center, cross-sectional, case-control study. ToM abilities were evaluated via "Reading the Mind in the Eyes Test" (RMET), "Faces Test", "Faux-Pas Test", "Comprehension Test" and "Unexpected Outcomes Test". Social responsiveness, pragmatic language and emotion regulation were evaluated by Social Responsiveness Scale (SRS), Children's Communication Checklist-Second Edition (CCC-2), Difficulties in Emotion Regulation Scale (DERS) and Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS). Within the study period, we enrolled 85 adolescents (42 with OCD and 43 controls).Results: The OCD group performed significantly lower than healthy controls in the Faux Pass and Comprehension tests (p = 0.003 for both). We found a statistically significant difference between groups in terms of the goal, strategy, non-acceptance subscales of the DERS (p < 0.001, p = 0.006, p = 0.008, respectively) as well as the total DERS score (p < 0.001). CY-BOCS total scores correlated significantly and negatively with Comprehension, Faux Pas and Unexpected Outcomes tests, and positively with CCC total, SRS total and DERS total scores. In regression analysis the DERS, SRS and CCC tests emerged as significant predictors of CY-BOCS total score.Conclusion: Addressing ToM, pragmatic, and ER difficulties when planning the treatment of young people with OCD may contribute to positive outcomes.Öğe The relationship between problematic internet use, sleep quality and impulsivity in adolescents with major depressive disorder(2019) Onat, Merve; Özyurt, Gonca; Öztürk, Yusuf; Akay, Aynur PekcanlarObjective: Problematic internet use and poor sleep quality are widespread problems in adolescents. The aim of this study is to investigate the relationship between problematic internet use, sleep quality and impulsivity in adoles- cents diagnosed with major depressive disorder and to compare the findings with those of healthy controls. Meth- ods: The study was planned as a single-disciplinary, three-centered, cross-sectional study with a control group. All participants were assessed using the Kiddie Schedule for Affective Disorders and Schizophrenia Present and Life- time Version (K-SADS-PL). Beck Depression Inventory (BDI), Barratt Impulsiveness Scale (BIS-11), Pittsburgh Sleep Quality Index (PSQI) and Young’s Internet Addiction Test (IAT) were administered to all participants. Results: It was determined that the total scores of BIS-11 scale, PSQI and IAT were statistically and significantly higher in the depression group than controls. In addition, a positive correlation was found between IAT and BIS-11 score and between IAT and PSQI. A positive correlation was also found between BIS-11 and PSQI. Conclusion: According to the findings of our study, it is suggested that there may be multiple and complex interactions between problematic internet use, low sleep quality, impulsivity and depressive symptoms. (Anatolian Journal of Psychiatry 2019; 20(5):491-498)Öğe Relationships between family functioning, parenting and peer victimization in adolescent depression: A cross-sectional study(Kare Publishing, 2021) Öztürk, Yusuf; Onat, Merve; Özyurt, Gonca; Mutlu, Caner; Tufan, Ali Evren; Akay, Aynur PekcanlarOBJECTIVE: Major depressive disorder (MDD) in adolescence is a prevalent mental health problem with a complex etiology and a rising incidence. The aim of the study investigated functioning of family, attitudes of parents, and peer victimization in adolescents with MDD and to compare those with healthy adolescents. METHODS: The study was designed as a multi-center, cross-sectional, case-control study. 98 adolescents diagnosed with MDD and 99 healthy controls were recruited for the study. Beck depression inventory, parental attitude research instrument (PARI) tool, family assessment device (FAD), and multidimensional peer victimization scale (MPVS) were applied to all participants. Descriptive, correlational, and bivariate group comparisons were used in analyses. RESULTS: The average ages of adolescents with MDD and control adolescents were 14.7 (S.D.=1.5) and 15.0 (S.D.=1.6) years, respectively. Females formed 74.5% of youth with MDD (vs. 70.3% of controls). The groups were similar in terms of socio-demographic features (all p>0.05). Adolescents with MDD had significantly elevated scores in FAD subscales except problem solving, PARI rejection of homemaking, marital conflict, and authoritarian subscales, and all MPVS subscales. Adolescents with MDD also displayed significant positive correlations between all MPVS subscales and FAD subscales except FAD problem-solving. CONCLUSION: This cross-sectional, multi-center study suggests that family dysfunction and peer victimization may be higher in youth with MDD. Although cross-sectional design precludes evaluation of causality, it may be prudent to evaluate family functions as well as peer victimization of depressed youth.Öğe Relationships between pediatric obesity and maternal emotional states and attitudes(Sage Publications Inc, 2015) Akay, Aynur Pekcanlar; Öztürk, Yeşim; Avcıl, Sibel Nur; Kavurma, Canem; Tufan, Evren AliObjective The goal of this study was to investigate depression and anxiety levels of mothers whose child (7-11 years) and adolescent (12-18 years) offspring had obesity, as well as those mothers' attitudes toward their children and their family relationships. Method This is a cross-sectional, case-control study of 100 dyads. All mothers completed the Beck Depression Inventory, the State-Trait Anxiety Inventory, the Parental Attitude Research Instrument, and the Family Assessment Device. Results Maternal state anxiety in the group with obesity was significantly higher than controls (p=0.03). As measured by Family Assessment Device, affective involvement (p=0.05) and behavior control (p=0.00) scores were significantly higher for those with obesity. Obesity and adolescence have independent effects on maternal state anxiety; affective involvement domain of family function is affected by both obesity and its interaction with adolescence, while behavior control domain is singularly affected by obesity. Conclusions Our results may demonstrate that, for the mothers of children who have obesity, this condition may have an adverse effect on their lives and their family relationships. Pediatric obesity and developmental stage of offspring may have different effects on maternally reported psychometric variables. Cross-sectional design may hinder causal explanations. Further studies with longitudinal designs are needed.Öğe Serum brain-derived neurotrophic factor levels in treatment?naïve boys with attention-deficit/hyperactivity disorder treated with methylphenidate: an 8-week, observational pretest-posttest study(Springer, 2018) Akay, Aynur Pekcanlar; Resmi, Halil; Güney, Sevay Alsen; Erkuran, Handan Özek; Özyurt, Gonca; Sargın, Enis; Topuzoğlu, Ahmet; Tufan, Ali EvrenBrain-derived neurotrophic factor (BDNF) is an important neurotrophin in the brain that modulates dopaminergic neurons. In this study, we aimed to investigate the changes in serum BDNF levels of children with attention-deficit/hyperactivity disorder (ADHD) in response to OROS methylphenidate treatment. We also aimed to determine whether there were any pre-post-differences between ADHD subtypes and comorbid psychiatric disorders in serum BDNF levels. Fifty male children with ADHD and 50 male healthy controls within the age range of 6-12 years were recruited to the study. The psychiatric diagnoses were determined by applying a structured interview with Kiddie schedule for affective disorders and schizophrenia for school-age children-present and lifetime version. The symptom severity of ADHD was measured using the Clinical Global Impression ADHD Severity Scale (CGI-S). Physicians completed Du Paul ADHD questionnaires. The levels of serum BDNF were assessed before and after 8 weeks of treatment with effective dosages of OROS methylphenidate. In the present study, the mean serum BDNF levels of boys with ADHD and of the healthy controls were 2626.33 +/- 1528.05 and 2989.11 +/- 1420.08 pg/mL, respectively. Although there were no statistically significant difference between the ADHD group and healthy controls at baseline (p = 0.22), the increase of serum BDNF was statistically significant from baseline to endpoint in the ADHD group (p = 0.04). The mean serum BDNF levels at baseline and endpoint of the ADHD group were 2626.33 +/- 1528.05 and 3255.80 +/- 1908.79 pg/mL, respectively. The serum BDNF levels of ADHD-inattentive subtype were significantly lower at baseline (p = 0.02), whereas BDNF levels post-treatment showed no significant difference. The increase of serum BDNF levels with methylphenidate treatment after 8 weeks was significantly higher in the inattentive group (p = 0.005). The increase of serum BDNF levels with methylphenidate treatment after 8 weeks in boys with ADHD may support the potential role of BDNF in the pathophysiology of ADHD. The role of BDNF in ADHD subtypes in particular should be evaluated with further, larger studies.
