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Relation between indices of end-organ damage and mean platelet volume in hypertensive patients
(2012) Bulur, Serkan; Önder, Halil Ibrahim; Aslantas, Yusuf; Ekinozu, Ismail; Kiliç, Aliça?r; Yalcin, Sübhan; Bulur, Şule
Mean platelet volume (MPV) has been recognized as an independent risk factor of hypertension. Hypertensive end-organ damage worsens the prognosis in hypertensive patients. We aimed to investigate the relationship between MPV levels and subclinical end-organ damage in hypertensive patients. One hundred and sixteen hypertensive patients (81 women, 35 men, with a mean age of 53 ± 11) were included in the study. There was no correlation between MPV and left-ventricular mass index (LVMI) (r = 0.145; P = 0.14) or albuminuria (r = 0.009; P = 0.93). Among the individuals that had grade I and grade II retinopathy, MPV levels (8.3 ± 2 fL, 8.2 ± 1.3 fL; P = 0.28) were similar either. We concluded that there was no correlation between MPV and markers of end-organ damage in hypertensive patients. Copyright © 2012 Lippincott Williams & Wilkins.