Platelet-lymphocyte ratio in predicting mortality of patients in pediatric intensive care unit
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Aim: Patients in the PICU have high rates of mortality. In this study we researched whether platelet-lymphocyte ratio (PLR), in addition to other scoring methods, is an early predictor of mortality risk in PICU patients. Material and Method: The patient files of children hospitalized in the PICU between 2014 and 2015 were examined. Results: A total of 670 patients were included (46.9% girls and 53.1% boys). 25 (3.7%) of these children died. In patients who died, the GCS was below 9, and PRISM, PELOD, and PIM2 scores were above 12, 7, and 90, respectively (p<0.001 for each factor). Significant cut-off values were 2 (p<0.001) for lactate (100% sensitivity, 64.3% specificity) and 3.9 (p<0.001) for PLR (80% sensitivity, 68.9% specificity). Diagnoses such as hematological-oncological diseases, sepsis, or multi-organ failure in children admitted to the PICU were factors affecting mortality (p=0.001, p=0.008, and p<0.001, respectively). Other factors affecting mortality were found to be high PIM2 scores (p=0.041), hyperlactatemia (p<0.001), and high PLR (p<0.001). Discussion: In addition to known scoring methods, PLR is a beneficial predictive factor of mortality rate in PICU patients.