Neuroborreliosis and autoimmunity, Guillain Barre syndrome: two case reports
YazarTurkoglu, Sule Aydin
Bolac, Elif Sultan
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Lyme disease is a multisystemic disease and involvement of the nervous system is called neuroborreliosis. Clinical manifestations of peripheral neuroborreliosis include asymmetric polyradiculopathy, cranial nerve paralysis, multifocal mononeuropathies and sensorymotor polyneuropathies. Guillain-Barre syndrome also known as acute inflammatory demyelinating polyneuropathy is an immune-mediated neuropathy. Only limited number of cases with Lyme disease presented with Guillain-Barre syndrome symptoms are encountered in the literature reviews, which are mostly seen during paediatric age. Herein we will report two patients with Guillain-Barre syndrome who presented with atypical findings and followed up in our clinic. In these cases diagnosis of Lyme disease was confirmed by Western Blot technique which demonstrated the presence of antibodies formed against Borrelia burgdorferi.