Evaluation of mean platelet volume and neutrophil to lymphocyte ratio as a diagnostic indicator in patients with recurrent aphthous stomatitis
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Objective: Recurrent aphthous stomatitis (RAS) is a chronic inflammatory disease of oral mucosa characterized by recurrent painful ulcers. Despite it is a condition seen frequently, its etiology and pathogenesis are not known fully. Its etiology is reportedly idiopathic or multifactorial. Mean platelet volume (MPV) indicates thrombocytic activation, while neutrophil/lymphocyte rate (NLR) is an indicator of chronic inflammation, and both of them can be measured during routine whole blood analysis. The aim of this study is to investigate MPV and NLR values in patients with RAS and the control group. Methods: A total of 39 patients with RAS and 34 control subjects were included in the study. Results: When the patient and the control groups were compared, MPV, ESR, CRP and vitamin B12 values were significantly higher in the patient group while NLR, WBC, hemoglobin, neutrophil and lymphocyte values were not significantly different between both groups. Conclusion: It was shown that MPV can be used as a diagnostic indicator in patients with RAS.