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dc.contributor.authorAltunrende, Burcu
dc.contributor.authorYildiz, Serpil
dc.contributor.authorCevik, Ayse
dc.contributor.authorYildiz, Nebil
dc.date.accessioned2021-06-23T19:35:49Z
dc.date.available2021-06-23T19:35:49Z
dc.date.issued2014
dc.identifier.issn1590-1874
dc.identifier.issn1590-3478
dc.identifier.urihttps://doi.org/10.1007/s10072-014-1653-4
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7872
dc.descriptionWOS:000338318000014en_US
dc.descriptionPubMed: 24487701en_US
dc.description.abstractOur aim was to compare the effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) over supplementary motor area with that of sham stimulation in restless legs syndrome (RLS). In this prospective study, patients were randomly assigned to either real stimulation group (11 patients), or sham stimulation group (8 patients) in a double-blinded fashion. Five patients, who were initially in the sham stimulation group, received real stimulation 1 month after the sham stimulation. One session of intervention was performed once every 3 days and total of ten sessions were done in each group. The International RLS-Rating Scale (IRLS-RS) was assessed at baseline and after 5th and 10th sessions in both groups and also in five patients in whom both sham and real stimulation were performed. A statistically significant difference was seen in the IRLS scores between real (n = 11) and sham stimulation (n = 8) after 5th and 10th sessions. The real stimulation significantly improved the IRLS-RS scores although they were unaffected by the sham stimulation. In five patients, in whom both sham and real stimulation were performed, a statistically significant improvement was seen in the IRLS-RS scores with the real stimulation and a statistically significant difference was seen in the IRLS scores between real and sham stimulation after 10th session. In conclusion, this method is safe and non-invasive, and the results of this pilot study may support that rTMS has the potential to be used in the treatment of RLS, which should be verified in larger series.en_US
dc.language.isoengen_US
dc.publisherSpringer-Verlag Italia Srlen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRestless legs syndromeen_US
dc.subjectRepetitive transcranial magnetic stimulationen_US
dc.subjectSupplementary motor areaen_US
dc.titleRepetitive transcranial magnetic stimulation in restless legs syndrome: preliminary resultsen_US
dc.typearticleen_US
dc.contributor.department[0-Belirlenecek]en_US
dc.contributor.authorID0000-0002-1845-0902en_US
dc.contributor.institutionauthor[0-Belirlenecek]
dc.identifier.doi10.1007/s10072-014-1653-4
dc.identifier.volume35en_US
dc.identifier.issue7en_US
dc.identifier.startpage1083en_US
dc.identifier.endpage1088en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.relation.journalNeurological Sciencesen_US


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