Serum uric acid (SUA) in morbidly obese patients and its relationship with metabolic syndrome
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Objective: This study aimed to compare serum uric acid levels in normal-weight peers and morbidly obese patients. Our second objective is to evaluate whether hyperuricemia is associated with metabolic syndrome components in morbidly obese patients. Methods: Fifty morbidly obese patients (40 males and 10 females) and 50 control groups (37 males and 13 females) were included in the study. Their baseline clinical characteristics and laboratory data were recorded and compared. Kolmogorov-Smirnov test was used to examine the normality of variables. Data were compared using univariate tests including independent samples t-test, Mann-Whitney U test, and chi-square test. Results: Compared to control group CRP, uric acid, urea, fasting plasma glucose, triglyceride, ALT, and AST were significantly higher in morbidly obese patients. HDL-cholesterol and GFR were significantly lower in morbidly obese patients. There were no significant differences in creatinine, LDL-cholesterol, and total cholesterol levels between two groups. Conclusion: Laboratory parameters, especially serum uric acid levels, were found to be higher in morbidly obese patients compared to the control group.