Browsing by Author "Yaykaşlı, Kürşat Oğuz"
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Amatoxin and phallotoxin concentration in Amanita phalloides spores and tissues
Kaya, Ertuğrul; Karahan, Selim; Bayram, Recep; Yaykaşlı, Kürşat Oğuz; Çolakoğlu, Serdar (Sage Publications Inc, 2015)Most of the fatal cases of mushroom poisoning are caused by Amanita phalloides. The amount of toxin in mushroom varies according to climate and environmental conditions. The aim of this study is to measure -, -, and -amanitin ... -
Düzce yöresinde yetişen Amanita Phalloides mantarındaki Alfa Amanitin düzeyinin Hplc yöntemiyle ölçümü
Kaya, Ertuğrul; Karahan, Selim; Hancı, Mustafa; Yaykaşlı, Kürşat Oğuz; Sarıtaş, Ayhan; Bayram, Recep (2012)Amaç: Düzce ili sınırlarında 2010 yılında toplanan Amanita phalloides mantarındaki alfa amanitin toksin düzeyinin HPLC yöntemiyle ölçümü amaçlanmıştır. Yöntem: Bir mantar bütün olarak, diğeri ise parçalara ayrılarak ... -
Erythropoietin stimulates patellar tendon healing in rats
Uslu, Mustafa; Kaya, Ertuğrul; Yaykaşlı, Kürşat Oğuz; Oktay, Murat; Inanmaz, Mustafa Erkan; Işık, Cengiz (Elsevier Science Bv, 2015)Backround: Erythropoietin (EPO), regulating erythropoiesis, is used to provide protective and regenerative activity in non-haematopoietic tissues. There is insufficient knowledge about the role of EPO activity in tendon ... -
Evaluation and comparison of alpha- and beta-amanitin toxicity on MCF-7 cell line
Kaya, Ertuğrul; Bayram, Recep; Yaykaşlı, Kürşat Oğuz; Yılmaz, İsmail; Bayram, Sait; Yaykaşlı, Emine; Yavuz, Muhsine Zeynep; Gepdiremen, Ali Akçahan (Tubitak Scientific & Technical Research Council Turkey, 2014)Background/aim: Alpha- and beta-amanitins are the main toxins of the poisonous Amanita phalloides mushroom. Although there are many studies available concerning alpha-amanitin, there are limited data about beta-amanitin ... -
Polymorphisms in MMP-2 and TIMP-2 in Turkish patients with prostate cancer
Yaykaşlı, Kürşat Oğuz; Kayıkçı, Muhammet Ali; Yamak, Nesibe; Soğuktaş, Hatice; Düzenli, Selma; Arslan, Ali Osman; Metin, Ahmet (2014)Aim: Prostate cancer is the most commonly diagnosed malignancy and the second most common cause of cancer deaths in the Western male population. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) modulate ... -
Purification and in vitro toxicity of gamma amanitin
Bakırcı, Sinan; Bayram, Recep; Yılmaz, İsmail; Yaykaşlı, Kürşat Oğuz; Bayram, Sait (Taylor & Francis Ltd, 2015)We aimed to obtain gamma amanitin with high purity through a purification process and compare toxic effects of alpha, beta, and gamma amanitin. Specific concentrations of the toxins (25, 10, 1, and 0.1 mu g/mL) were applied ... -
What is the restoring role of chrysin in alpha amanitin toxicity?
Bakırcı, Sinan; Bayram, Recep; Kaya, Ertuğrul; Yaykaşlı, Kürşat Oğuz; Yılmaz, İsmail (Carbone Editore, 2015)Aim: To explore whether chrysin has any protective effect against the deadly effect of alpha amanitin on hepatocytes that is one of the major toxins in the structure of Amanita phalloides, which is considered the most ... -
Yüksek saflıkta beta amanitin üretimi
Kaya, Ertuğrul; Yaykaşlı, Kürşat Oğuz; Karahan, Selim; Bayram, Recep; Sarıtaş, Ayhan; Yaykaşlı, Emine (2012)Amaç: Beta amanitin nadiren bilimsel araştırmalarda kullanılmakta ve kullanımı gün geçtikçe artmaktadır. Piyasada bu ürün %90 saflıkta ticari olarak satılmaktadır. Bu araştırmada yüksek saflıkta beta amanitin üretme yöntemi ...