Browsing by Author "Tosun, Mehmet"
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Alleviation of kidney damage induced by unilateral ureter obstruction in rats by rhodiola rosea
Üyetürk, Uğur; Terzi, E. Hakan; Kemahlı, Eray; Gücük, Adnan; Tosun, Mehmet; Çetinkaya, Ayhan (Mary Ann Liebert, Inc, 2013)Purpose: To evaluate the efficacy of Rhodiola rosea extract in terms of alleviating the renal damage induced by unilateral ureter obstruction (UUO) in rats. Material and Methods: Thirty Wistar albino male rats were divided ... -
Antioxidant Characteristic of Pretreatment Hypericum Perforatum Oil Administration in a Rabbit Model of Palatal Mucosal Injury
Objective: This study was aimed to determine the antioxidant and soft tissue wound healing properties of pretreatment (p) of topical Hypericum perforatum (HP) oil in rabbits.Materials and Methods: Thirty-six New Zealand ... -
Aqueous humour and serum concentration of asymmetric dimethyl arginine in pseudoexfoliation syndrome
Tosun, Mehmet; Erdurmuş, Mesut; Buğdaycı, Güler; Çelebi, Serdal; Alçelik, Aytekin (Bmj Publishing Group, 2012)Objective Asymmetric dimethyl arginine (ADMA) is the major endogenous inhibitor of nitric oxide synthase. ADMA is related to endothelial dysfunction and is an independent cardiovascular risk factor. This study aimed to ... -
Association between omentin levels and insulin resistance in pregnancy
Aktaş, Gülali; Alçelik, Aytekin; Özlü, Tülay; Tosun, Mehmet; Tekçe, Buket Kın; Savlı, Haluk; Tekçe, Hikmet (Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2014)Aims: Omentin is a new adipokine secreted mainly from visceral adipose tissue. Serum omentin is found to be reduced in patients with impaired glucose tolerance, type 2 diabetes mellitus, obesity and insulin resistant states. ... -
The Association of Omentin Levels in Non-Diabetic Postmenopausal Women with Bone Mineral Density and Total Body Composition
Özlü, Tülay; Sarman, Hakan; Alçelik, Aytekin; Işık, Cengiz; Yazıcı, Selma; Tosun, Mehmet; Caglar, Hilal (2015)Objectives: Positive relation between body mass and bone mineral density (BMD) is thought to be due to weight bearing effect. However, adipose tissue derived adipokines may have important effects on bone. Obese women have ... -
Asymmetric dimethylarginine levels in allergic rhinitis and nasal polyposis
Tosun, Mehmet; Apuhan, Tayfun (Tubitak Scientific & Technical Research Council Turkey, 2013)Aim: Asymmetric dimethylarginine (ADMA) is the major endogenous inhibitor of nitric oxide synthase. We aimed to investigate the ADMA levels in allergic rhinitis (AR) and nasal polyposis (NP). Materials and methods: A total ... -
Asymmetric dimethylarginine levels in patients with cutaneous anthrax: a laboratory analysis
Sünnetçioğlu, Mahmut; Mengeloğlu, Zafer; Baran, Ali İrfan; Karahocagil, Mustafa; Tosun, Mehmet; Küçükbayrak, Abdülkadir; Akdeniz, Hayrettin (Bmc, 2014)Background: Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase, is considered to be associated with endothelial dysfunction. High ADMA levels have been shown to be related with ... -
Carbon dioxide insufflation causes upper urinary tract injury in the early period of an experimental vesicoureteral reflux model
Kılınçaslan, Hüseyin; Gündoğdu, Gökhan; Terzi, Elçin Hakan; Öztürk, Hülya; Fırat, Tülin; Tosun, Mehmet (Springer, 2013)Ureteral reimplantation via pneumovesicum is a new aspect of vesicoureteral reflux management. We aimed to determine the effects of carbon dioxide (CO2) insufflation on the upper urinary tract in an experimental model. ... -
Cardiac autonomic function in healthy young smokers
Erdem, Alim; Ayhan, Suzi Selim; Öztürk, Serkan; Özlü, Mehmet Fatih; Alçelik, Aytekin; Tosun, Mehmet; Gümüştekin, Kenan; Yazıcı, Mehmet (Sage Publications Inc, 2015)The present study examined the heart rate turbulence (HRT) and heart rate variability (HRV) parameters in healthy young smokers (<40years) to assess the effects of smoking on cardiac autonomic function. The study included ... -
Comparing the HbA1c assay results of architect C 8000 and MQ-2000PT
Tekçe, Buket Kın; Tekçe, Hikmet; Aktaş, Gülali; Tosun, Mehmet (Galenos Yayıncılık, 2015)Objective: Changes in a device and the modification of measurement methods are frequent issues in medical laboratories. The effects of such modifications on assay results should be investigated. HbA1c is a widely used ... -
Comparison of the values of free testosterone with free androgen index
Amaç: Testosteron erkeklerde birincil ve ikincil seks karakterlerinin gelişmesinden başlıca sorumlu hormon- dur. Ancak birçok biyokimyasal parametrede olduğu gibi testosteronun biyolojik aktif olan kısmı, serbest olanıdır. ... -
Could thrombocyte parameters be an inflammatory marker in the brucellosis?
Küçükbayrak, Abdülkadir; Taş,Tekin; Tosun, Mehmet; Aktaş, Gülali; Alçelik, Aytekin; Hakyemez, İsmail Necati; Koçoğlu, Esra (Medical Association of Zenica-Doboj Canton, 2013)Aim To investigate links between platelet parameters mean platelet volume (MPV), platelet count (PC), platelet distribution width (PDW), platelet mass (PM) and brucella tube agglutination titers (BSTAT) in patients with ... -
Diabetes mellitus increases plasma cardiothrophin - levels independently of heart failure and hypertension
Aktaş, Gülali; Alçelik, Aytekin; Tosun, Mehmet; Öztürk, Serkan; Özlü, Mehmet Fatih; Savlı, Haluk; Yazıcı, Mehmet (Carbone Editore, 2013)Aims: Cardiothrophin-1 (CT-1) is a novel 201 amino acid cytokine that has pleiotropic protective effects in apoptosis, hepatic injury, myocardial infection and contrast nephropathy. CT-1 predicts a variety of disorders ... -
The diagnostic significance of NT-proBNP and troponin I in emergency department patients presenting with palpitations
Ocak, Tarık; Erdem, Alim; Duran, Arif; Tekelioğlu, Ümit Yaşar; Öztürk, Serkan; Ayhan, Suzi Selim; Özlü, Mehmet Fatih; Tosun, Mehmet; Koçoğlu, Hasan; Yazıcı, Mehmet (Hospital Clinicas, Univ Sao Paulo, 2013)OBJECTIVE: This prospective study investigated the diagnostic significance of the N-terminal pro-brain natriuretic (NT-proBNP) and troponin I peptides in emergency department patients presenting with palpitations. METHODS: ... -
Effects of energy drinks on serum VEGF and bFGF levels during wound healing
Toptaş, Orçun; Tek, Mustafa; Akkaş, İsmail; Kazancıoğlu, Hakkı Oğuz; Tosun, Mehmet; Özan, Fatih (Carbone Editore, 2015)Introduction: Energy drinks consist of many substances like caffeine, taurine, sucrose/glucose, vitamins and some herbal supplements like ginseng, gingko biloba and guarana and are used by millions of people world-wide. ... -
Effects of ivabradine therapy on heart failure biomarkers
Ordu, Serkan; Yıldız, Bekir Serhat; Alihanoğlu, Yusuf İzzettin; Özsoy, Aybars; Tosun, Mehmet (Via Medica, 2015)Background: Heart rate (HR) reduction is associated with improved outcomes in patients with heart failure (HF) and biomarkers can be a valuable diagnostic tool in HF management. The primary aim of our study was to evaluate ... -
Effects of N-acetyl cysteine on lipid levels and on leukocyte and platelet count in rats after splenectomy
Şit, Mustafa; Yılmaz,, E. E.; Tosun, Mehmet; Aktaş, Gülali (Medknow Publications & Media Pvt Ltd, 2014)Introduction: Many of studies have shown that increased lipid levels play a significant role in the pathogenesis of atherosclerosis after splenectomy. We investigated the effects of N-acetyl cysteine (NAC) on lipid parameters ... -
Effects of the inflammatory response on serum omentin levels in early acute and chronic pancreatitis
Şit, Mustafa; Aktaş, Gülali; Yılmaz, Edip Erdal; Alçelik, Aytekin; Terzi, Elçin Hakan; Tosun, Mehmet (Societa Editrice Universo, 2014)Background and Aims: Acute pancreatitis is an acute inflammation of the parenchyma of the pancreas. Several adipokines have been investigated in acute pancreatitis, and these cytokines contribute to inflammation in acute ... -
Erythrocytes parameters in the course of brucellosis
Küçükbayrak, Abdülkadir; Taş, Tekin; Tosun, Mehmet; Aktaş, Gülali; Hakyemez, İsmail Necati; Mengeloğlu, Fırat Zafer; Akdeniz, Hayrettin (2013)Amaç: Bruselloz hastalarında tüm eritrosit parametrelerini değerlendirmek ve bu parametreler ile inflamatuar belirte çler arasındaki ilişkiyi araştırmak. Yöntem: Çalışmaya brusella tüp aglütinasyon pozitif toplam 55 hasta ... -
Evaluation of left atrial mechanical functions and atrial conduction abnormalities in patients with clinical hypothyroid
Öztürk, Serkan; Dikbaş, Oğuz; Özyaşar, Mehmet; Ayhan, Selim; Özlü, Fatih; Erdem, Alim; Yazıcı, Mehmet; Alçelik, Aytekin; Tosun, Mehmet (Via Medica, 2012)Background: The aim of this study was to investigate left atrial (LA) mechanical functions, atrial electromechanical delay and P wave dispersion in hypothyroid patients. Methods: Thirty-four patients with overt hypothyroid ...