Browsing by Author "Torun, İbrahim Ethem"
Now showing items 1-7 of 7
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Capsaicin attenuates excitotoxic-induced neonatal brain injury and brain mast cell-mediated neuroinflammation in newborn rats
Kılınç, Yasemin Baranoğlu; Dilek, Mustafa; Kılınç, Erkan; Torun, İbrahim Ethem; Şaylan, Aslıhan; Düzcü, Selma Erdoğan (Elsevier Ireland Ltd, 2023)Excitotoxicity and neuroinflammation are key contributors to perinatal brain injuries. Capsaicin, an active ingredient of chili peppers, is a potent exogenous agonist for transient receptor potential vanilloid 1 receptors. ... -
The effects of certain TRP channels and voltage-gated KCNQ/Kv7 channel opener retigabine on calcitonin gene-related peptide release in the trigeminovascular system
Çıtak, Arzu; Kılınç, Erkan; Torun, İbrahim Ethem; Ankaralı, Seyit; Dağıstan, Yaşar; Yoldaş, Hamit (Sage Publications Ltd, 2022)Background Calcitonin gene-related peptide release in trigeminovascular system is a pivotal component of neurogenic inflammation underlying migraine pathophysiology. Transient receptor potential channels and voltage-gated ... -
Esculetin alleviates pentylenetetrazole-induced seizures, cognitive impairment and pro-inflammatory cytokines and suppresses penicillin-induced epileptiform activity in rats
Danış, Ayşegül; Kılınç, Yasemin Baranoğlu; Torun, İbrahim Ethem; Hancı, Fatma; Kılınç, Erkan; Ankaralı, Handan (Pergamon-Elsevier Science Ltd, 2023)Aims: To investigate the effects of different doses of esculetin on epileptiform activity, behavioral seizures, memory impairment, and cortical and hippocampal NF-Kappa B, as a mediator of pro-inflammatory gene induction, ... -
Mast cell activation alleviates pentylenetetrazole-induced epileptic seizures via serotonin in rats
Kılınç, Erkan; Torun, İbrahim Ethem; Çetinkaya, Ayhan; Töre, Fatma (KARGER, 2021)Mast cell activation alleviates pentylenetetrazole-induced epileptic seizures via serotonin in rats -
Mast cell activation ameliorates pentylenetetrazole-induced seizures in rats: the potential role for serotonin
Kılınç, Erkan; Torun, İbrahim Ethem; Çetinkaya, Ayhan; Töre, Fatma (Blackwell Publishing Ltd, 2021)Neuroinflammation plays a key role in the pathogenesis of epilepsy, but the underlying mechanisms are not well understood. Mast cells are multifunctional immune cells that are also activated by stress. The effects of ... -
Receptor mechanisms mediating the anti-neuroinflammatory effects of endocannabinoid system modulation in a rat model of migraine
Kılınç, Erkan; Ankaralı, Seyit; Torun, İbrahim Ethem; Dağıstan, Yaşar (Wiley, 2020)Calcitonin gene-related peptide (CGRP), substance P and dural mast cells are main contributors in neurogenic inflammation underlying migraine pathophysiology. Modulation of endocannabinoid system attenuates migraine pain, ...
