Browsing by Author "Firat, Tulin"
Now showing items 1-20 of 27
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4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-beta-D-glucopyranoside effect in liver regeneration
Firat, Tulin; Soyler, Gizem; Tore, Fatma; Sit, Mustafa; Kiyan, Aysu; Ozgen, Ufuk; Kukner, Aysel (F Hernandez, 2019)Following an injury or resection, the mammalian liver has the capacity to regain its former volume and functioning by restoring itself. Studies have demonstrated that antioxidants play a role in hepatic regeneration. This ... -
Carbon dioxide insufflation causes upper urinary tract injury in the early period of an experimental vesicoureteral reflux model
Kilincaslan, Huseyin; Gundogdu, Gokhan; Terzi, Elcin Hakan; Ozturk, Hulya; Firat, Tulin; Tosun, Mehmet (Springer, 2013)Ureteral reimplantation via pneumovesicum is a new aspect of vesicoureteral reflux management. We aimed to determine the effects of carbon dioxide (CO2) insufflation on the upper urinary tract in an experimental model. ... -
Comparison of Histopathological Effects of Thymoquinone and Local Nasal Corticosteroids in Allergic Rhinitis in a Rabbit Model
Yurttas, Veysel; Sereflican, Murat; Erkocoglu, Mustafa; Dagli, Muharrem; Terzi, Elcin Hakan; Firat, Tulin; Seyhan, Sinan (Karger, 2016)Background/Aims: In this study, we aimed to evaluate the histopathological effects of thymoquinone treatment of the nasal mucosa in a rabbit model of allergic rhinitis, and we compared its effects with those of nasal ... -
Comparison of the effect of intravitreal bevacizumab and intravitreal fasudil on retinal VEGF, TNF alpha, and caspase 3 levels in an experimental diabetes model
Celik, Fatih; Ulas, Fatih; Ozunal, Zeynep Gunes; Firat, Tulin; Celebi, Serdal; Dogan, Umit (Ijo Press, 2014)AIM: To evaluate the influence of an intravitreal injection of bevacizumab and fasudil on the retinal vascular endothelial growth factor (VEGF), tumor necrosis factor alpha (TNF alpha), and caspase 3 levels in a diabetic ... -
Does platelet-rich plasma enhance micro fracture treatment for chronic focal chondral defects? An in-vivo study performed in a rat model
Hapa, Onur; Cakici, Husamettin; Yuksel, Halil Yalcin; Firat, Tulin; Kukner, Aysel; Aygun, Hayati (Turkish Assoc Orthopaedics Traumatology, 2013)Objective: The purpose of the present study was to compare the effectiveness of platelet-rich plasma (PRP) + microfracture and microfracture treatments in the healing of chronic focal chondral defects. Methods: The study ... -
The effect of kisspeptin on spermatogenesis and apoptosis in rats
Ayturk, Nilufer; Firat, Tulin; Kukner, Aysel; Ozogul, Candan; Tore, Fatma; Kandirali, Ismail Engin; Yilmaz, Bayram (Tubitak Scientific & Technical Research Council Turkey, 2017)Background/aim: To study the effect of kisspeptin, a gonadotropin release stimulator, on the testicular tissue of the rat. Materials and methods: Four groups were formed as follows: control, Kiss-10 50 nmol administration ... -
Effect of Mitomycin, Bevacizumab, and 5-Fluorouracil to Inhibit Urethral Fibrosis in a Rabbit Model
Uyeturk, Ugur; Gucuk, Adnan; Firat, Tulin; Kemahli, Eray; Kukner, Aysel; Ozyalvacli, Mehmet Emin (Mary Ann Liebert, Inc, 2014)Background and Purpose: Mitomycin C (MMC), bevacizumab, and 5-fluorouracil (5-FU) are frequently used in cancer treatment. Each of these agents also exhibits antiproliferative properties in different tissues. We compared ... -
EFFECT OF MONTELUKAST ON ACUTE LUNG INJURY INDUCED BY INTESTINAL ISCHEMIA AND REPERFUSION IN RATS
Terzi, E. Hakan; Duran, Arif; Firat, Tulin; Ocak, Tarik; Kukner, Aysel (Carbone Editore, 2014)Aims: Lungs are the most affected remote organs after intestinal ischemia/reperfusion. The aim of our study is to investigate the effects of montelukast on intestinal ischemia/reperfusion-induced acute pulmonary injury, ... -
Effects of Energy Drinks on Soft Tissue Healing
Tek, Mustafa; Toptas, Orcun; Akkas, Ismail; Kazancioglu, Hakki Oguz; Firat, Tulin; Ezirganli, Seref; Ozan, Fatih (Lippincott Williams & Wilkins, 2014)The aim of the present study was to investigate the effects of an energy drink (ED) on soft tissue wound healing in the rat model. Thirty-six male Wistar albino rats were randomly divided into 2 groups. A full-thickness ... -
Effects of nicorandil on renal function and histopathology in rats with partial unilateral ureteral obstruction
Ozturk, Hayrettin; Firat, Tulin; Tekce, Buket Kin; Yilmaz, Fahri; Ozturk, Hulya (Elsevier Taiwan, 2017)To evaluate the effects of nicorandil in a rat kidney model of partial unilateral ureteral obstruction (PUUO). Thirty male rats were randomly divided into three groups as follows: (1) Group 1 (Sham-control), ureters of the ... -
Effects of omentin on flap viability: an experimental research on rats
Efeoglu, Fatih Burak; Gokkaya, Ali; Karabekmez, Furkan Erol; Firat, Tulin; Gorgu, Metin (Taylor & Francis Ltd, 2019)Background: Viability decreases at the distal parts with an increase in the length of flaps. In this study, we evaluated the effects of subcutaneously administered omentin on flap viability, where it is applied to distal ... -
Effects of Stellate Ganglion Block on Healing of Fractures Induced in Rats
Kizilay, Hasan; Cakici, Husamettin; Kilinc, Erkan; Firat, Tulin; Kuru, Tolgahan; Sahin, A. Alper (Hindawi Ltd, 2020)Objective. Sympathetic blocks are used as an adjunct for pain management in the treatment of orthopedic and traumatic conditions. Stellate ganglion (ganglion stellatum) provides sympathetic innervation of the head, neck ... -
The effects of vasoactive intestinal peptide on duramater mast cells and C-FOS activity of trigeminal nucleus at sympathectomized rats
Tore, Fatma; Kilinc, Erkan; Firat, Tulin; Kukner, Aysel; Tuncel, Nese (Humana Press Inc, 2012)[No Abstract Available] -
Electrophysiological Evaluation of the Effect of Minoxidil on Penicillin-G-Induced Epilepsy in Rats
Cetinkaya, Ayhan; Gokdas, Serhat; Orallar, Hayriye; Firat, Tulin; Camsari, Cagri; Fidan, Esra (Wiley, 2019)[No Abstract Available] -
Evaluation of the Effect of Topical Hypericum perforatum Oil on Excisional Palatal Wound Healing in Rabbits
Gunpinar, Sadiye; Kilic, Olgu Alperat; Duran, Ismet; Tosun, Mehmet; Firat, Tulin; Soyler, Gizem (Taylor & Francis Inc, 2020)Aim: The aim of this study was to evaluate the effect of Hypericum perforatum (HP) oil on wound-healing process in rabbit palatal mucosa. Materials and Methods: Thirty-six New Zealand albino rabbits were randomly allocated ... -
Evaluation of the effects of melatonin administration intraperitoneally on rats with acute pancreatitis induced by ductal ligation
Col, Cavit; Dinler, Kahraman; Hasdemir, Oguz; Buyukasik, Oktay; Firat, Tulin; Kukner, Aysel (Aves, 2010)Background/aims: The aim of this study was to address the protective effects of exogenous melatonin injections intraperitoneally on the histopathological changes in a model of obstructive acute pancreatitis. Methods: In ... -
An experimental study on effects of pyrrolidine dithiocarbamate on ischemia-reperfusion injury in testis
Kemahli, Eray; Yildiz, Mevlut; Firat, Tulin; Ozyalvacli, Mehmet Emin; Uyeturk, Ugur; Yilmaz, Burak; Gucuk, Adnan (Canadian Urological Association, 2016)Introduction: The aim of this experimental study was to investigate the histopathological and biochemical effects of pyrrolidine dithiocarbamate, an antioxidant and inhibitor of NF-k beta, on ischemia-reperfusion injury ... -
Modulation of xenobiotic metabolizing enzyme activities in rat liver by co-administration of morin, endosulfan, and 7,12-dimethylbenz[a]anthracene
Sapmaz, Canan; Firat, Tulin; Kukner, Aysel; Bozcaarmutlu, Azra (Taylor & Francis Ltd, 2020)Morin is a flavonoid which is present in many plants. Endosulfan and 7,12-dimethylbenz[a]anthracene (DMBA) are toxic chemicals that humans are exposed to in their daily lives. In this study, the protective role of morin ... -
Outcomes from Cyanoacrylate Use in Tracheal Anastomosis in a Rat Model
Bicer, Yusuf Ozgur; Koybasi, Serap; Seyhan, Sinan; Firat, Tulin; Kazaz, Hasan (Sage Publications Ltd, 2015)Objectives We aimed to investigate the histologic effects of N-butyl-2-cyanoacrylate (NBCA) and metacryloxisulfolane (MS) comonomer on tracheal anastomosis in vivo on a rat model of tracheal resection and end-to-end ... -
The preventive effect of low molecular weight heparin on CCL4-induced necrosis and apoptosis in rat liver
Kukner, Aysel; Tore, Fatma; Firat, Tulin; Terzi, E. Hakan; Oner, Hakan; Balaban, Yasemin H.; Ozogul, Candan (Elsevier Espana, 2010)Introduction Heparin having anti inflammatory and anti fibrotic properties may have therapeutic effect on liver injury The present study investigated the effect of low molecular weight heparin (Enoxaparin) on carbon ...
