Browsing by Author "Fırat, Tülin"
Now showing items 1-20 of 40
-
7-Ethoxyresorufin O-deethylase and glutathione S-transferase activities of rats treated with morin, 7,12-dimethylbenz[a] anthracene and endosulfan
Sapmaz, Canan; Fırat, Tülin; Kükner, Aysel; Bozcaarmutlu, Azra (Wiley-Blackwell, 2016)[No Abstract Available] -
Antioxidant Characteristic of Pretreatment Hypericum Perforatum Oil Administration in a Rabbit Model of Palatal Mucosal Injury
Objective: This study was aimed to determine the antioxidant and soft tissue wound healing properties of pretreatment (p) of topical Hypericum perforatum (HP) oil in rabbits.Materials and Methods: Thirty-six New Zealand ... -
Carbon dioxide insufflation causes upper urinary tract injury in the early period of an experimental vesicoureteral reflux model
Kılınçaslan, Hüseyin; Gündoğdu, Gökhan; Terzi, Elçin Hakan; Öztürk, Hülya; Fırat, Tülin; Tosun, Mehmet (Springer, 2013)Ureteral reimplantation via pneumovesicum is a new aspect of vesicoureteral reflux management. We aimed to determine the effects of carbon dioxide (CO2) insufflation on the upper urinary tract in an experimental model. ... -
Comparison of histopathological effects of thymoquinone and local nasal corticosteroids in allergic rhinitis in a rabbit model
Yurttaş, Veysel; Şereflican, Murat; Erkoçoğlu, Mustafa; Dağlı, Muharrem; Terzi, Elçin Hakan; Fırat, Tülin; Seyhan, Sinan (Karger, 2016)Background/Aims: In this study, we aimed to evaluate the histopathological effects of thymoquinone treatment of the nasal mucosa in a rabbit model of allergic rhinitis, and we compared its effects with those of nasal ... -
Comparison of the effect of intravitreal bevacizumab and intravitreal fasudil on retinal VEGF, TNF alpha, and caspase 3 levels in an experimental diabetes model
Çelik, Fatih; Ulaş, Fatih; Özünal, Zeynep Güneş; Fırat, Tülin; Çelebi, Serdal; Doğan, Ümit (Ijo Press, 2014)AIM: To evaluate the influence of an intravitreal injection of bevacizumab and fasudil on the retinal vascular endothelial growth factor (VEGF), tumor necrosis factor alpha (TNF alpha), and caspase 3 levels in a diabetic ... -
Çinkodan zengin diyetin, sigara dumanı maruziyetindeki sıçan mesane dokusu sitokin profiline etkisi
Hakan, Elçin Terzi; Kükner, Aysel; Aydın, Hatip; Özyalvaçlı, Mehmet Emin; Fırat, Tülin; Üyetürk, Uğur (2015)Amaç: Sigara içimi akciğer, larinks, özefagus, mide, mes ane ve böbrek kanserleri ile kronik hastalıkların sebebidir. Sitokinler, inflamasyonun başlatılması ve sürdürülmesinde önemlidirler. Sigara, çinko eksikliği sebebidir. ... -
Deneysel karaciğer hasarının akciğer dokusuna etkisi ve mast hücrelerinin rolü
Fırat, Tülin; Ulaş, Nilüfer; Terzi, E. Hakan; Töre, Fatma; Kükner, Aysel (Türkiye Klinikleri Tıp Bilimleri Dergisi, 2013)Amaç: Deneysel karaciğer hasarına bağlı oluşan akciğer dokusu ve mast hücre sayısındaki değişikliklerin ışık mikroskobik olarak incelenmesi. Gereç ve Yöntemler: Bu çalışmada yetişkin Wistar albino ratlar kullanıldı. Ratlar ... -
Does platelet-rich plasma enhance micro fracture treatment for chronic focal chondral defects? An in-vivo study performed in a rat model
Hapa, Onur; Çakıcı, Hüsamettin; Yüksel, Halil Yalçın; Fırat, Tülin; Kükner, Aysel (Turkish Assoc Orthopaedics Traumatology, 2013)Objective: The purpose of the present study was to compare the effectiveness of platelet-rich plasma (PRP) + microfracture and microfracture treatments in the healing of chronic focal chondral defects. Methods: The study ... -
The effect of erythropoietin to pulmonary injury and mast cells secondary to acute pancreatitis
Korkmaz, Taner; Kahramansoy, Nurettin; Kılıçgün, Ali; Fırat, Tülin (BioMed Central Ltd., 2014)Background: Acute pancreatitis is a life-threatening necroinflammatory disease that is characterized by systemic inflammatory response syndrome and acute lung injury even in its very first days. Erythropoietin (EPO) is a ... -
The effect of kisspeptin on spermatogenesis and apoptosis in rats
Background/aim: To study the effect of kisspeptin, a gonadotropin release stimulator, on the testicular tissue of the rat. Materials and methods: Four groups were formed as follows: control, Kiss-10 50 nmol administration ... -
Effect of mitomycin, bevacizumab, and 5-Fluorouracil to inhibit urethral fibrosis in a rabbit model
Üyetürk, Uğur; Gücük, Adnan; Fırat, Tülin; Kemahlı, Eray; Kükner, Aysel; Özyalvaçlı, Mehmet Emin (Mary Ann Liebert, Inc, 2014)Background and Purpose: Mitomycin C (MMC), bevacizumab, and 5-fluorouracil (5-FU) are frequently used in cancer treatment. Each of these agents also exhibits antiproliferative properties in different tissues. We compared ... -
Effect of montelukast on acute lung injury induced by intestinal ischemia and reperfusion in rats
Terzi, Elçin Hakan; Duran, Arif; Fırat, Tülin; Ocak, Tarık; Kükner, Aysel (Carbone Editore, 2014)Aims: Lungs are the most affected remote organs after intestinal ischemia/reperfusion. The aim of our study is to investigate the effects of montelukast on intestinal ischemia/reperfusion-induced acute pulmonary injury, ... -
The effect of resveratrol and glibenclamide on ischemia/reperfusion induced arrhythmias in STZ-induced diabetic rats
Kaya, Salih Tunç; Özaslan, Oğulcan Talat; Ekşioglu, Didem; Erim, Firdevs; Yaşar, Selçuk; Bozdoğan, Ömer; Fırat, Tülin (Wiley-Blackwell, 2016)Context: Cardiovascular dysfunctions such as life-threatening arrhythmias are one of the main reasons of mortality and morbidity in diabetic patients Objective: We aimed to investigate the long-term effects of resveratrol, ... -
The effects of combined vitamin C and vitamin E in streptozotocin-induced diabetic rat kidney
Diabetic nephropathy is a serious complication of diabetes mellitus. Oxidative stress has been suggested to play a key role in the pathogenesis of diabetic nephropathy. Vitamins C and E play important roles in the antioxidant ... -
Effects of energy drinks on soft tissue healing
Tek, Mustafa; Toptaş, Orçun; Akkaş, İsmail; Kazancıoğlu, Hakkı Oğuz; Fırat, Tülin; Ezirganlı Şeref; Ozan, Fatih (Lippincott Williams & Wilkins, 2014)The aim of the present study was to investigate the effects of an energy drink (ED) on soft tissue wound healing in the rat model. Thirty-six male Wistar albino rats were randomly divided into 2 groups. A full-thickness ... -
Effects of nicorandil on renal function and histopathology in rats with partial unilateral ureteral obstruction
Öztürk, Hayrettin; Fırat, Tülin; Tekçe, Buket Kin; Yılmaz, Fahri; Öztürk, Hülya (Elsevier Taiwan, 2017)To evaluate the effects of nicorandil in a rat kidney model of partial unilateral ureteral obstruction (PUUO). Thirty male rats were randomly divided into three groups as follows: (1) Group 1 (Sham-control), ureters of the ...
