Browsing by Author "Dağıstan, Yaşar"
Now showing items 1-20 of 26
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Atipik klinik prezantasyon gösteren bir Bartter sendromu olgusu
Bartter sendromu Henle kulpunun çıkan kalın kolundaki taşıyıcı proteinlerin etkisini ortadan kaldıran mutasyonlar nedeniyle ortaya çıkmaktadır. Oluşan klinik bulgular kompleksi, esas olarak tübüler sodyum ve klorür kaybının ... -
Cervical sympathectomy modulates the neurogenic inflammatory neuropeptides following experimental subarachnoid hemorrhage in rats
Dağıstan, Yaşar; Kılınç, Erkan; Balcı, Cemre Nur (Elsevier, 2019)Background: Neuroinflammation is implicated in cerebral vasospasm and brain injuries after subarachnoid hemorrhage (SAH). In addition to classical neuroinflammation with increased inflammatory cytokines, a sterile neurogenic ... -
The Comparison of Effects of Applications of Compound 48/80 and Mast Cell Mediator Suspension on Inflammation in Rats: A Methodological Study for Acute Inflammatory Pain
Objective: Inflammation underlies the pathological basis of most diseases. Substance-P is a key mediator that participates in various inflammatory processes and painful conditions. Mast cells (MCs) have a key role in ... -
The comparison of the effects of application of compound 48/80 and autologous mast cell mediator suspension on plasma substance-P levels and dural mast cells in rats: a methodological study for acute Inflammatory Pain
Kılınç, Erkan; Dağıstan, Yaşar; Çetinkaya, Ayhan; Töre, Fatma (Wiley, 2017)[No Abstract Available] -
Could red cell distribution width and mean platelet volume be a predictor for lumbar disc hernias?
Dağıstan, Yaşar; Dağıstan, Emine; Gezici, Ali Rıza; Halıcıoğlu, Sıdıka; Akar, Semih; Özkan, Nezih; Aktaş, Gülali (Literatura Medica, 2016)Background Lumbar disc herniation (LDH) causes major disabilities worldwide. Several studies in the literature had reported the correlation between radiculopathy and inflammatory markers. Mean platelet volume (MPV), red ... -
Effects of black cumin seeds and certain species of fungi extracts on the number and degranulation of mast cells in dura mater in rats
Kılınç, Erkan; Dağıstan, Yaşar (Wiley-Blackwell, 2016)[No Abstract Available] -
The effects of certain TRP channels and voltage-gated KCNQ/Kv7 channel opener retigabine on calcitonin gene-related peptide release in the trigeminovascular system
Çıtak, Arzu; Kılınç, Erkan; Torun, İbrahim Ethem; Ankaralı, Seyit; Dağıstan, Yaşar; Yoldaş, Hamit (Sage Publications Ltd, 2022)Background Calcitonin gene-related peptide release in trigeminovascular system is a pivotal component of neurogenic inflammation underlying migraine pathophysiology. Transient receptor potential channels and voltage-gated ... -
Effects of cobalt nitrate on histopathological and morphometric changes in rat femoral artery vasospasm model
Uçar, Saygın; Dağıstan, Yaşar; Güler, Ali (Coll Physicians & Surgeons Pakistan, 2016)Objective: To determine the effects of cobalt nitrate on the arterial wall in a rat femoral artery vasospasm model. Study Design: Experimental study. Place and Duration of Study: Faculty of Medicine, Istanbul University, ... -
Effects of minimally invasive decompression surgery on quality of life in older patients with spinal stenosis
Dağıstan, Yaşar; Dağıstan, Emine; Gezici, Ali Riza; Cancan, Seçkin Emre; Bilgi, Murat; Çakır, Uğur (Elsevier, 2015)Objectives: Lumbar spinal stenosis (LSS) in the elderly may result in a progressive narrowing of the spinal canal leading to compression of nerve roots in some individuals. The aim of this study was to evaluate the quality ... -
Effects of Nigella sativa seeds and certain species of fungi extracts on number and activation of dural mast cells in rats
Kılınç, Erkan; Dağıstan, Yaşar; Kotan, Batuhan; Çetinkaya, Ayhan (Akademiai Kiado Rt, 2017)In this study, we aimed to investigate the effects of Nigella sativa seeds and certain species of fungi extracts on the number and degranulation states of dural mast cells in rats. Rats were fed ad libitum with normal tap ... -
Effects of sagittal balance differences on spondylolisthesis
Coşgun, Zeliha; Dağıstan, Emine; Dağıstan, Yaşar (Atha Comunicacao & Editora, 2019)Objectives: This study aimed to compare the lumbar lordosis (LL) and spinopelvic parameters of patients with stage 1-2 spondylolisthesis to those of the normal population and demonstrate the importance of these parameters ... -
Efficacy of the greater occipital nerve block in recurrent migraine type headaches
Ökmen, Korgün; Dağıstan, Yaşar; Dağıstan, Emine; Kaplan, Necati; Cancan, Emre (Via Medica, 2016)Aims: We aimed to evaluate six months of results following repeated GON blocks. Methods: We evaluated the results from GON block performed on 60 patients. Briefly, we applied a standard 2 mL of 0.5% Bupivacaine GON blockage ... -
Evaluation of simple blood counts as inflammation markers for brain tumor patients
Dağıstan, Yaşar; Dağıstan, Emine; Çıtışlı, Veli (Termedia Publishing House Ltd, 2016)Aims: Hemogram parameters in routine blood panels have been proposed as inflammation markers. These parameters, especially the red cell distribution width (RDW) and mean platelet volume (MPV), were evaluated as surrogate ... -
Importance of IL-6, MMP-1, IGF-1, and BAX levels in lumbar herniated disks and posterior longitudinal ligament in patients with sciatic pain
Dağıstan, Yaşar; Çukur, Selma; Dağıstan, Emine; Gezici, Ali Rıza (Elsevier Science Inc, 2015)PURPOSE: The aim of this study was to evaluate prognostic importance of interleukin-6 (IL-6), matrix metalloproteinase (MMP)-1, insulin-like growth factor (IGF)-1, and Bcl-2-associated X protein (BAX) levels in biopsy ... -
Lomber Disk Hernili hastalarda ağrı depresyon İlişkisi
Dağıstan, Yaşar; Dağıstan, Emine (2017)Giriş ve Amaç: Bel ağrısı yüksek insidansa sahip ve önemli derecede iş gücü kaybına ve sağlık harcamalarına yol açan ciddi bir sağlık problemidir. Kronik bel ağrısı olan kişilerin depresyona daha yatkın olduğu bildirilmiştir. ... -
Lomber Disk Hernisi ve Hemogram Parametreleri Arasında Bir Bağlantı Var mı?
Amaç: Enflamatuvar mekanizmalar disk hernisi ile ilişkili bel ağrısının patogenezinde önemli bir rol oynamaktadır. Rutin hemogram testlerindeki yeni ve umut vadeden enflamatuvar belirteçler ortalama trombosit hacmi (mean ... -
Mast cell degranulation mediates compound 48/80-induced meningeal vasodilatation underlying migraine pain
Kılınç, Erkan; Dağıstan, Yaşar; Töre, Fatma (Marmara Univ, Inst Health Sciences, 2018)Objective: The cranial dura mater contains plenty of mast cells and is principally supplied by the middle meningeal artery which has a key role in the generation of headaches. Neurogenic inflammation caused by perivascular ... -
Receptor mechanisms mediating the anti-neuroinflammatory effects of endocannabinoid system modulation in a rat model of migraine
Kılınç, Erkan; Ankaralı, Seyit; Torun, İbrahim Ethem; Dağıstan, Yaşar (Wiley, 2020)Calcitonin gene-related peptide (CGRP), substance P and dural mast cells are main contributors in neurogenic inflammation underlying migraine pathophysiology. Modulation of endocannabinoid system attenuates migraine pain, ... -
Role of expression of inflammatory mediators in primary and recurrent lumbar disc herniation
Dağıstan, Yaşar; Çukur, Selma; Dağıstan, Emine; Gezici, Ali Rıza (Korean Neurosurgical Soc, 2017)Objective: To assess role of some inflammatory mediators in patients with primary and recurrent lumbar disc herniation. Expression of IL-6, transforming growth factor (TGF)-1, insulin-like growth factor (IGF)-1, and ... -
Salmon calcitonin ameliorates migraine pain through modulation of CGRP release and dural mast cell degranulation in rats
Kılınç, Erkan; Dağıstan, Yaşar; Kükner, Aysel; Yılmaz, Bayram; Ağuş, Sami (Wiley, 2018)The exact mechanism of migraine pathophysiology still remains unclear due to the complex nature of migraine pain. Salmon calcitonin (SC) exhibits antinociceptive effects in the treatment of various pain conditions. In this ...
