Browsing by Author "Can, Güray"
Now showing items 1-20 of 31
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Age-based computer-aided diagnosis approach for pancreatic cancer on endoscopic ultrasound images
Özkan, Murat; Çakıroğlu, Murat; Kocaman, Orhan; Kurt, Mevlüt; Yılmaz, Bülent; Can, Güray; Korkmaz, Uğur (Wolters Kluwer Medknow Publications, 2016)Aim: The aim was to develop a high-performance computer-aided diagnosis (CAD) system with image processing and pattern recognition in diagnosing pancreatic cancer by using endosonography images. Materials and Methods: On ... -
Bactericidal permeability increasing protein gene polymorphism is associated with inflammatory bowel diseases in the Turkish population
Can, Güray; Akın, Hakan; Özdemir, Filiz Türe; Can, Hatice; Yılmaz, Bülent (Medknow Publications & Media Pvt Ltd, 2015)Background/Aims: Inflammatory bowel disease, a chronic inflammatory disease with unknown etiology, affects the small and large bowel at different levels. It is increasingly considered that innate immune system may have a ... -
Beliefs about medicines and adherence to treatment in Turkish patients with inflammatory bowel disease
Can, Güray; Yozgat, Ahmet; Tezel, Ahmet; Ünsal, Gülbin; Soylu, Ali Rıza (AVES, 2022)Background: Although studies are investigating the perception and beliefs about treatment and adherence to treatment in different societies related to inflammatory bowel disease, there are no studies on this subject in ... -
Characteristics of patients with hepatocellular carcinoma: A multicenter study
Güzelbulut, Fatih; Karaoğullarından, Ümit; Akkız, Hikmet; Altıntaş, Engin; Demirtaş, Coşkun Özer; Can, Güray (Kare Publishing, 2022)Background and Aim: The aim of the present study was to examine the etiology of hepatocellular carcinoma (HCC) by underlying cause and determine the characteristics and clinical features of patients with HCC. Materials and ... -
Chronic hepatitis B associated with hepatic steatosis, insulin resistance, necroinflammation and fibrosis
Yılmaz, Bülent; Köklü, Seyfettin; Büyükbayram, Hüseyin; Yalçın, Kendal; Korkmaz, Uğur; Poşul, Emrah; Can, Güray; Kurt, Mevlüt (Makerere Univ, Fac Med, 2015)Background: The effect of hepatitis B virus (HBV) infection on fatty liver disease is unclear.. Objectives: The aim of this study was to investigate the viral and host causes of fatty liver in chronic hepatitis B (CHB) ... -
Combination of novel c.3484g > t/p.glu162ter variant in abcb11 and c.208g > a/p.asp70asn variant in atp8b1 are associated with severe symptoms in progressive family ıntrahepatic cholestasis
Bekdaş, Mervan; Can, Güray; Eröz, Recep; Düzcü, Selma Erdoğan (Georg Thieme Verlag Kg, 2020)Progressive family intrahepatic cholestasis (PFIC) is an autosomal recessive disease that causes chronic cholestasis. It is associated with pathogenic variants in genes that encode proteins involved in bile secretion to ... -
Comparison of the efficacy of entecavir and tenofovir in reducing hepatocellular carcinoma risk in chronic hepatitis b patients: A real-life study in Turkey
Güzelbulut, Fatih; Gökçen, Pınar; Can, Güray; Adalı, Gupse; Saltürk, Ayça Gökçen Değirmenci (AVES, 2021)Background: It is controversial whether entecavir or tenofovir differs in reducing hepatocellular carcinoma (HCC) risk. We aimed to compare the efficacy of entecavir and tenofovir in reducing HCC risk in chronic hepatitis ... -
Correlation between physician disease assessment in ulcerative colitis and burden of disease: ICONIC 2-year data of 120 patients in Turkey
Sezgin, Orhan; Atuğ, Özlen; Gönen, C.; Can, Güray; Duman, Ali Erkan; Erzin, Yusuf Ziya (Oxford University Press, 2021)Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD), and the overall burden is increasing at the global level. Differences in perceptions of UC-related burden may highlight dramatic degree ... -
Efficacy and safety of direct-acting antivirals in elderly patients with chronic hepatitis C: A nationwide real-life, observational, multicenter study from Turkey
Önlen, Yusuf; Bal, Tayibe; Çabalak, Mehmet; Çuvalcı, Nefise Öztoprak; Sarı, Nagehan Didem; Can, Güray; Sırmatel, Fatma (2022)Background: The number and proportion of elderly patients living with chronic hepatitis C are expected to increase in the coming years. We aimed to compare the real-world efficacy and safety of direct-acting antiviral ... -
The efficacy of tyrosine kinase inhibitor dasatinib on colonic mucosal damage in murine model of colitis
Can, Güray; Ayvaz, Süleyrnan; Can, Hatice; Karaboğa, İhsan; Demirtaş, Selim; Korkmaz, Uğur; Kurt, Mevlüt (Elsevier Masson, Corporation Office, 2016)Background and objective: Ulcerative colitis is an inflammatory condition of the colon in the gastrointestinal system. Currently, the most potent medications used for ulcerative colitis produce no response in 20-30% of ... -
Epidemiologic features of inflammatory bowel disease in Western Blacksea region of Turkey for the last 10 years: Retrospective cohort study
Can, Güray; Poşul, Emrah; Yılmaz, Bülent; Can, Hatice; Korkmaz, Uğur; Ermiş, Fatih (Korean Assoc Internal Medicine, 2019)Background/Aims: There are only a few epidemiological study about inflammatory bowel disease in the last 10 years in Turkey, especially in Western Blacksea region. In our study, we aimed to identify the changes in the ... -
Evaluation of epicardial adipose tissue and carotid intima-media thickness as a marker of atherosclerosis in patients with inflammatory bowel disease
Ekmen, Nergiz; Can, Güray; Yozgat, Ahmet; Can, Hatice; Bayraktar, Muhammed Fatih; Demirkol, Muhammed Emin; Kayhan, Meral Akdoğan; Sasani, Hadi (ARÁN EDICIONES, S.L., 2021)Background and aim: this study aimed to compare carotid intima media (CIMT) and epicardial adipose tissue (EAT) measurements, which are considered as markers for the detection of early atherosclerosis in healthy ... -
Gamma-glutamyl-transferase may predict COVID-19 outcomes in hospitalised patients
Kasapoğlu, Benan; Yozgat, Ahmet; Tanoğlu, Alpaslan; Can, Güray; Sakin, Yusuf Serdar (Wiley-Hindawi, 2021)Aim In this study, we aimed to define the predictive role of liver function tests at admission to the hospital in outcomes of hospitalised patients with COVID-19. Material and Method In this multicentric retrospective ... -
In a real-life setting, direct-acting antivirals to people who inject drugs with chronic hepatitis C in Turkey
Yıldırım, Figen Sarıgül; Üser, Ülkü; Sarı, Nagehan Didem; Kurtaran, Behice; Önlen, Yusuf; Can, Güray; Sırmatel, Fatma (AVES, 2022)Background: People who inject drugs (PWID) should be treated in order to eliminate hepatitis C virus in the world. The aim of this study was to compare direct-acting antivirals treatment of hepatitis C virus for PWID and ... -
Investigation of IL23R, JAK2, and STAT3 gene polymorphisms and gene-gene interactions in Crohn's disease and ulcerative colitis in a Turkish population
Can, Güray; Tezel, Ahmet; Gürkan, Hakan; Tozkır, Hilmi; Ünsal, Gülbin (Aves, 2016)Background/Aims: Inflammatory bowel diseases are chronic, relapsing, inflammatory conditions. They have a genetic backround resulting in patient susceptibility. The aim of our study is to investigate the involvement of ... -
Is there any link between atrial arrhythmias and inflammatory bowel disease?
Can, Güray; Can, Hatice; Bayraktar, Muhammet Fatih; Demirkol, Muhammed Emin; Kayhan, Meral Akdoğan; Sasani, Hadi; Ekmen, Nergiz (Wolters Kluwer Medknow Publications, 2021)Background: Inflammation plays an important role in the development of cardiovascular disease, including atherosclerosis and arrhythmia. The aim of this study was to evaluate atrial conduction times (ACTs) in patients with ... -
Komplike apandisitin neden olduğu tekrarlayan iliopsoas apse olgusu
Şit, Mustafa; Çakır, Affan; İkiz, Özgür; Posul, Emrah; Yılmaz, Bülent; Can, Güray; Kurt, Mevlüt (2014)Bağırsağa komşu ikincil bir enfeksiyon kaynağı iliopsoas apseye (İPA) neden olabilir. Perfore akut apandisitin ciddi bir komplikasyonu olarak iliopsoas apse nadiren görülebilir. Tekrarlayan iliopsoas apse öyküsü olan 76 ... -
Long-term proton pump inhibitor use is a risk factor for mortality in patients hospitalized for COVID-19
Yozgat, Ahmet; Kasapoğlu, Benan; Can, Güray; Tanoğlu, Alpaslan; Sakin, Yusuf Serdar; Yalçın, Kadir Serkan; Gürler, Müjgan (Scientific Technical Research Council Turkey-TÜBİTAK, 2021)Background and aim: The aim of this study is to evaluate whether the long-term (≥4 weeks) use of proton pump inhibitors (PPIs) is a risk factor for intubation requirement and mortality in patients hospitalized for ...