Browsing by Author "Astarcı, Erhan"
Now showing items 1-5 of 5
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Carbazole substituted BODIPY dyes :synthesis, photophysical properties and antitumor activity
Şengül, İbrahim Fazıl; Okutan, Elif; Kandemir, Hakan; Astarcı, Erhan; Çoşut, Bünyemin (Elsevier Sci Ltd, 2015)In this study, two different BODIPYs containing carbazole groups at the mesa position were designed and synthesized. All compounds were fully characterized by elemental analysis, FT-IR, matrix-assisted laser desorption/ionization ... -
The effect of sub-chronic systemic ethanol treatment on corpus cavernosal smooth muscle contraction: the contribution of RhoA/Rho-kinase
Kumcu, Eda Karabal; Aydınoğlu, Fatma; Astarcı, Erhan; Öğülener, Nuran (Springer, 2016)The aim of this study was to evaluate whether the sub-chronic systemic ethanol exposure has direct effect on cavernosal smooth muscle contractions induced by KCl (depolarizing) and phenylephrine (alpha(1)-receptor agonist), ... -
Effects of ethanol on RhoA/Rho-kinase-mediated calcium sensitization in mouse lung parenchymal tissue
Aydınoğlu, Fatma; Kıroğlu, Olcay Ergürhan; Astarcı, Erhan; Ballı, Ebru; Öğülener, Nuran (Elsevier Science Bv, 2015)Calcium sensitization by the RhoA/Rho-kinase (ROCK) pathway contributes to the contraction in smooth muscle. Contractile stimuli can sensitize myosin to Ca2+ by activating RhoA/Rho-kinase that inhibits myosin light chain ... -
An in vitro and in vivo investigation of the cytotoxic effects of caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester and bortezomib in multiple myeloma cells
Background/aim: In this study, the in vitro and in vivo effectiveness of caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester (CAPE) in combination with bortezomib, a proteasome inhibitor, was explored in multiple ... -
Synthesis of novel pyrrolo[3,2-c]carbazole and dipyrrolo[3,2-c: 2 ',3 '-g]carbazole derivatives
Şengül, İbrahim Fazıl; Astarcı, Erhan; Kandemir, Hakan (Georg Thieme Verlag Kg, 2016)Pyrrolocarbazole and dipyrrolocarbazoles have been synthesized via the Hemetsberger indole synthesis, starting from 9-ethyl carbazole-3-carbaldehyde and 9-ethylcarbazole-3,6-dicarbaldeyde, respectively. The pyrrolocarbazole ...
