Browsing by Author "Çolakoğlu, Neriman"
Now showing items 1-11 of 11
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Anti-inflammatory effect of cortistatin in rat endotoxin-induced uveitis model
Balbaba, Mehmet; Dal, Ali; Çolakoğlu, Neriman; Bulmuş, Özgür; Ulaş, Fatih; Yıldırım, Hakan; Aydemir, Orhan (Wolters Kluwer Medknow Publications, 2020)Purpose: To evaluate the anti-inflammatory effect of cortistatin (CST) in endotoxin-induced uveitis (EIU) model and to compare the results with corticosteroid treatment. Methods: A total of 35 healthy Wistar albino rats ... -
Effect of decorin and bevacizumab on oxygen-induced retinopathy in rat models: a comparative study
Güler, Seda Duran; Balbaba, Mehmet; Çolakoğlu, Neriman; Bulmuş, Özgür; Ulaş, Fatih; Eröksüz, Yesari (Wolters Kluwer Medknow Publications, 2021)Purpose: The aims of this study were to evaluate the effects of decorin (DCN) in rat oxygen-induced retinopathy (OIR) model and to compare the results with those of bevacizumab. Methods: Twenty-eight newborn Sprague-Dawley ... -
The effects of combined vitamin C and vitamin E in streptozotocin-induced diabetic rat kidney
Diabetic nephropathy is a serious complication of diabetes mellitus. Oxidative stress has been suggested to play a key role in the pathogenesis of diabetic nephropathy. Vitamins C and E play important roles in the antioxidant ... -
Effects of high dose retinoic acid on TGF-beta 2 expression during pancreatic organogenesis
Çolakoğlu, Neriman; Kükner, Aysel; Öner, Jale; Sönmez, M. Fatih; Öner, Hakan; Ozan, Enver (Springer, 2005)The aim of this study was to investigate the effects of excess all-trans retinoic acid, a vitamin A metabolite, on pancreatic organogenesis and TGF-beta 2 expression during prenatal development in rats. First group of ... -
The effects of triiodothyronine on rat testis: a morphometric and immunohistochemical study
Öner, Jale; Öner, Hakan; Çolakoğlu, Neriman; Kükner, Aysel; Ozan, Enver (Springer, 2006)The aim of present study was to investigate the effects of 3,3',5-triiodothyronine (T(3)) on rat testis both morphometrically and immunohistochemically with determining of insulin-like growth factor I (IGF-I) expression. ... -
Immunolocalization of TGF-beta 2 in the rat thymus during late stages of prenatal development
Sönmez, Mehmet Fatih; Çolakoğlu, Neriman; Kükner, Aysel; Ozan, Enver; Dabak, Dürrin Özlem (Elsevier Gmbh, 2009)The aim of this study was to investigate the immunolocalization of transforming growth factor beta (TGF-beta 2) in rat thymic stromal cells and thymocytes and investigate the roles of TGF-beta 2 in thymopoiesis during the ... -
Kadmiyum klorürün sıçan böbrek dokusunda oluşturduğu yapısal değişiklikler ve bu değişiklikler üzerine metallothioneinin etkileri: Işık mikroskobik çalışma
Kara, Haki; Çolakoğlu, Neriman; Kükner, Aysel; Ozan, Enver (2004)Amaç: Bu çalışmada kadmiyum klorür uygulaması ile böbrek dokusunda meydana gelen yapısal değişiklikler ve kadmiyum klorür ile birlikte ekzojen uygulanan metallothioneinin koruyucu etkilerinin ışık miroskobik incelenmesi ... -
Leptin in corneas from keratoconus and infectious keratitis patients
Aydemir, Orhan; Nazıroğlu, Mustafa; Çolakoğlu, Neriman; Yılmaz, Turgut; Kükner, Aysel; Kükner, A. Şahap (Mary Ann Liebert, Inc, 2005)Purpose: Leptin is produced primarily by adipose tissue. More recent studies have shown extra sites of leptin production in physiologic and ill human tissues. However, whether leptin originates from human corneas in ... -
Protective effects of intraperitoneal vitamin c, aprotinin and melatonin administration on retinal edema during experimental uveitis in the guinea pig
Kükner, A. Şahap; Kükner, Aysel; Nazıroğlu, Mustafa; Çolakoğlu, Neriman; Çelebi, Serdal; Yılmaz, Turgut; Aydemir, Orhan (Wiley, 2004)A considerable amount of clinical and experimental evidence exists suggesting the involvement of reactive oxygen substances (ROS) in the actiology of uveitis. The activated phagocytic system of polymorphonuclear leucocytes ... -
Sıçan testis dokusunda kadmiyum klorür’ün oluşturduğu yapısal değişiklikler ve bu değişiklikler üzerine metallothionein’nin etkileri: Elektron mikroskobik çalışma
Amaç: Bu çalışmada, testiküler dokuda kadmiyum klorürün sebep olduğu yapısal değişiklikler ve bu değişiklikler üzerine koruyucu amaçla uygulanan metallothioneinin etkilerinin belirlenmesi amaçlandı. Gereç Yöntem: 36 adet ... -
Ultrastructural changes in the kidney of rats with acute exposure to cadmium and effects of exogenous metallothionein
Kükner, Aysel; Çolakoğlu, Neriman; Kara, Haki; Öner, Hakan; Özoğul, Candan; Ozan, Enver (Humana Press Inc, 2007)Ultrastructural changes in the kidneys of rats after acute cadmium exposure and the effects of exogenous metallothionein (MT) were studied by transmission electron microscopy. Thirty-six adult Wistar rats were divided into ...
