Browsing by Author "Çetinkaya, Ayhan"
Now showing items 1-20 of 47
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Alleviation of kidney damage induced by unilateral ureter obstruction in rats by rhodiola rosea
Üyetürk, Uğur; Terzi, E. Hakan; Kemahlı, Eray; Gücük, Adnan; Tosun, Mehmet; Çetinkaya, Ayhan (Mary Ann Liebert, Inc, 2013)Purpose: To evaluate the efficacy of Rhodiola rosea extract in terms of alleviating the renal damage induced by unilateral ureter obstruction (UUO) in rats. Material and Methods: Thirty Wistar albino male rats were divided ... -
Ameliorating effect of hawthorn (Crataegus oxyacantha) and physical exercise on acute penicillin induced seizures in gerbils
Çakır, Serkan; Orallar, Hayriye; Çetinkaya, Ayhan; Kayacan, Yıldırım; Önal, Ali Can; Yıldırım, Arzu; Benek, Selim; Özkan, Murat; Okur, Nezih (African Networks Ethnomedicines, 2016)Background: The aim of the present study was to assess the effect of Hawthorn (Crataegus oxyacantha) and physical activity. We studied its effect on penicillin induced epilepsy. in gerbils. Materal and Methods: Epilepsy ... -
Can excessive oxygen cause hyperactive behavior disorder in preterm children? Cognitive effects of hyperoxia in the preterm brain of rats
Dilek, Mustafa; Orallar, Hayriye; Çetinkaya, Ayhan; Bozat, Gökçe; Pehlivan, Fatma; Bekdaş, Mervan; Kabakuş, Nimet (Springer, 2019)There is a paucity of data on the effects of hyperoxia-induced brain damage on learning and such psychosocial phenomenon as anxiety. Preterm infants encounter hyperoxia within a relatively early stage of life (leaving the ... -
Carvacrol attenuates histopathogic and functional impairments induced by bilateral renal ischemia/reperfusion in rats
Öztürk, Hülya; Çetinkaya, Ayhan; Düzcü, Selma Erdoğan; Tekçe, Buket Kın; Öztürk, Hayrettin (Elsevier France-Editions Scientifiques Medicales Elsevier, 2018)Background: Renal ischemia/reperfusion injury is the most common cause of acute kidney injury, which frequent occurrence in critically ill patients. Objectives: The aim of this study was to investigate the role of Carvacrol ... -
Carvacrol reduces the severity of intestinal mucosal damage caused by intestinal ischemia - Reperfusion in rats
Öztürk, Hülya; Çetinkaya, Ayhan; Düzcü, Selma Erdoğan; Yis, Özgür Mehmet; Öztürk, Hayrettin (Soc Stiinte Farmaceutice Romania, 2019)Intestinal ischemia-reperfusion (I/R) is a pathophysiological process that is common in many clinical conditions such as shock, sepsis, mesenteric thrombosis, necrotizing enterocolitis, and bowel transplantation. Our aim ... -
The Comparison of Effects of Applications of Compound 48/80 and Mast Cell Mediator Suspension on Inflammation in Rats: A Methodological Study for Acute Inflammatory Pain
Objective: Inflammation underlies the pathological basis of most diseases. Substance-P is a key mediator that participates in various inflammatory processes and painful conditions. Mast cells (MCs) have a key role in ... -
The comparison of the effects of application of compound 48/80 and autologous mast cell mediator suspension on plasma substance-P levels and dural mast cells in rats: a methodological study for acute Inflammatory Pain
Kılınç, Erkan; Dağıstan, Yaşar; Çetinkaya, Ayhan; Töre, Fatma (Wiley, 2017)[No Abstract Available] -
Comparison of the effects of topical corneal inhibitory agents on TTL and PON1 in rats
Soydan, Adem; Yazar, Hayrullah; Çetinkaya, Ayhan; Terzi, Elçin Hakan; Ulaş, Fatih; Doğan, Ümit (Rjpbcs Research Journal Pharmaceutical, Biological & Chemical Sciences, 2017)The aim of this study was to compare the effects of topical corneal inhibitory agents on total thiol (TTL) and paraoxonase 1 (PON1) levels in rats with experimentally acquired keratoconjunctivitis. Thirty-five rats were ... -
Development of venous thromboembolism in patients with hereditary thrombophilic risk factors and evaluation of genetic and biochemical parameters affecting development of venous thromboembolism
Korkmaz, Ufuk Turan Kürşat; Çetinkaya, Ayhan; Yüksel, Ahmet; Velioğlu, Yusuf; Uçaroğlu, Erhan Renan; Arslan, Ali Osman; Erdem, Kemalettin (2020)Objectives: To evaluate patients diagnosed with venous thromboembolism (VTE) in terms of hereditary thrombophilic risk factors and to assess genetic and biochemical factors affecting the development of VTE. Methods: Sixty ... -
Different exercise intensity and oxidative stress responses: thiol/disulfide homeostasis
Kayacan, Yıldırım; Çetinkaya, Ayhan; Yazar, Hayrullah; Makaracı, Yücel (Wiley, 2018)[No Abstract Available] -
Dynamic thiol/disulphide homeostasis metrics as a risk factor for peripheral arterial disease
Korkmaz, Ufuk Turan Kürşat; Yüksel, Ahmet; Çetinkaya, Ayhan; Velioğlu, Yusuf; Uçaroğlu, Erhan Renan; Erdem, Kemalettin (Sage Publications Ltd, 2021)Objective To examine dynamic thiol/disulphide homeostasis metrics as a novel risk factor of oxidative stress in patients with peripheral arterial disease. Methods One hundred patients with lower extremity peripheral arterial ... -
Effect of acute and chronic ellagic acid administration on penicillin-induced epileptiform activity in rats
Beyazçiçek, Ersin; Ankaralı, Seyit; Beyazçiçek, Özge; Ankaralı, Handan; Çetinkaya, Ayhan (Wiley, 2017)[No Abstract Available] -
The effect of rose oil on penicillin-induced epileptiform activity in rats: An electrophysiological study
Ankaralı, Seyit; Beyazçiçek, Ersin; Kılınç, Erkan; Beyazçiçek, Özge; Özkan, Kayhan; Çetinkaya, Ayhan (2018)Objective: Rose oil (from Rosa damascene) has several effects which are analgesic, antispasmodic, antioxidant and neuroprotective role. Its antiepileptic effect has not been yet studied enough. In the present study, it was ... -
The effect of vortioxetine on penicillin-induced epileptiform activity in rats
Ögün, Muhammed Nur; Çetinkaya, Ayhan; Beyazçiçek, Ersin (Assoc Arquivos Neuro- Psiquiatria, 2019)Vortioxetine is a multimodal antidepressant agent that modulates 5-HT receptors and inhibits the serotonin transporter. It is indicated especially in cases of major depressive disorder related to cognitive dysfunction. ... -
Effects of carvacrol administration on motor function following spinal ischemia and reperfusion
Çetinkaya, Ayhan; Çamsarı, Çağrı (Tubitak Scientific & Technical Research Council Turkey, 2020)The sensitivity of the medulla spinalis to ischemia and reperfusion has been shown in previous in vitro and in vivo studies. However, less is known about the effects of carvacrol administration following ischemia and ... -
Effects of estrogen and progesterone on the neurogenic inflammatory neuropeptides: Implications for gender differences in migraine
Çetinkaya, Ayhan; Kılınç, Erkan; Çamsarı, Çağrı; Ögün, Muhammed Nur (Springer, 2020)Neurogenic inflammation including calcitonin gene-related peptide (CGRP) and substance-P (SP) release plays a pivotal role in migraine pathogenesis. Prevalence of migraine is similar to 3 folds higher in women than in men, ... -
The effects of nigella sativa extract and chronic exercise application on penicillin-induced epilepsy model in Mongolian gerbils
Çetinkaya, Ayhan; Demir, Şerif; Orallar, Hayriye; Kayacan, Yıldırım; Beyazçiçek, Ersin (Wiley-Blackwell, 2016)Aim: To evaluate the role of treadmill exercise on the oxidative stress in Mongolian gerbils with penicillin-induced epilepsy. Methods: This experimental study included 18 male Mongolian gerbils which were divided into ... -
Effects of Nigella sativa seeds and certain species of fungi extracts on number and activation of dural mast cells in rats
Kılınç, Erkan; Dağıstan, Yaşar; Kotan, Batuhan; Çetinkaya, Ayhan (Akademiai Kiado Rt, 2017)In this study, we aimed to investigate the effects of Nigella sativa seeds and certain species of fungi extracts on the number and degranulation states of dural mast cells in rats. Rats were fed ad libitum with normal tap ... -
Efficient doxorubicin loading to isolated dexosomes of immature JAWSII cells: Formulated and characterized as the bionanomaterial
Mutlu, Esra Cansever; Kaya, Özge; Wood, Matthew; Mager, Imre; Topkara, Kübra Çelik; Çamsarı, Çağrı; Yıldırım, Arzu Birinci; Çetinkaya, Ayhan (Mdpi, 2020)Immature dendritic cells (IDc), 'dexosomes', are promising natural nanomaterials for cancer diagnose and therapy. Dexosomes were isolated purely from small-scale-up production by using t25-cell-culture flasks. Total RNA ... -
Electrophysiological evaluation of the effect of minoxidil on penicillin-g-Induced epilepsy in rats
Çetinkaya, Ayhan; Gökdaş, Serhat; Orallar, Hayriye; Fırat, Tülin; Çamsarı, Çağrı; Fidan, Esra (Wiley, 2019)[No Abstract Available]
